ProMIS Neurosciences Inc

ProMIS Neurosciences Inc (PMN) Stock Analysis

$13.785

-0.203 (-1.47%)At close

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High
14.600
Open
14.070
VWAP
13.95
Vol
51.47K
Mkt Cap
29.01M
Low
13.470
Amount
718.15K
EV/EBITDA, TTM
0.00

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.

AI analysis of ProMIS Neurosciences Inc (PMN)

buy

ProMIS Neurosciences Inc (PMN) appears to be a good buy right now due to its promising clinical trial results for PMN310, which showed a favorable safety profile and significant declines in disease-relevant biomarkers. The current price is $13.79, and analysts have raised their price targets significantly, with Guggenheim setting a target of $69, suggesting a potential upside of over 400%. Additionally, the stock has seen a year-to-date change of +93.20%, indicating strong momentum. However, the company has reported negative net income in recent quarters, with a loss of $11,729,656 in Q2 2026, which remains a risk for investors.

Valuation Metrics

The current forward P/E ratio for ProMIS Neurosciences Inc (PMN) is 0.00, compared to its 5-year average forward P/E of -1.27.

Forward P/E

Fair
5Y Average P/E
-1.27
Current P/E
0.00
Overvalued
0.44
Undervalued
-2.98

Forward EV/EBITDA

Overvalued
5Y Average EV/EBITDA
-1.31
Current EV/EBITDA
0.00
Overvalued
-0.32
Undervalued
-2.30

Forward P/S

Fair
5Y Average P/S
2456.47
Current P/S
0.00
Overvalued
7075.47
Undervalued
-2162.52

Alphio AI Price Scenarios for PMN

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%PMN

$0.45

Scenario price

B

Base

Base · 50%PMN

$0.44

Scenario price

B

Bear

Bear · 25%PMN

$0.40

Scenario price

Whales holding PMN

D

Deep Track Capital, LP

+ HoldingPMN

-3.79%

3M Return

Events Timeline

2026-08-13 (ET)

16:30:00

ProMIS Ends Q2 with $53.4 Million in Cash

2026-07-28 (ET)

06:30:00

ProMIS Neurosciences Reports Positive Interim Results for PMN310 Trial

2026-07-14 (ET)

06:03:00

ProMIS PMN310 Shows Dose-Dependent AbetaO Reduction at 3 and 29 Days at AAIC 2026

2026-05-12 (ET)

06:40:00

ProMIS Expects Cash Resources to Fund Operations Through 2027

2026-03-25 (ET)

17:30:00

ProMIS Neurosciences Files $200M Mixed Securities Shelf

News

PMN FAQ — answered by Alphio AI

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

ProMIS Neurosciences Inc (PMN) appears to be a good buy right now due to its promising clinical trial results for PMN310, which showed a favorable safety profile and significant declines in disease-relevant biomarkers. The current price is $13.79, and analysts have raised their price targets significantly, with Guggenheim setting a target of $69, suggesting a potential upside of over 400%. Additionally, the stock has seen a year-to-date change of +93.20%, indicating strong momentum. However, the company has reported negative net income in recent quarters, with a loss of $11,729,656 in Q2 2026, which remains a risk for investors.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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