ProMIS Neurosciences Inc

ProMIS Neurosciences Inc (PMN) Stock Analysis

$4.030

+0.420 (+10.41%)At close

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High
4.330
Open
3.760
VWAP
4.02
Volume
374.92K
Mkt Cap
29.01M
Low
3.700
Amount
1.51M
EV/EBITDA, TTM
0.00

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.

AI analysis of ProMIS Neurosciences Inc (PMN)

Sell

ProMIS Neurosciences Inc is not a good buy right now due to its extremely low RSI of 20.628, indicating oversold conditions, and a staggering 5-day price change of -62.78%. The stock is currently trading at $3.00, significantly below its 52-week high of $27.40, which raises concerns about its viability. While analysts have set a price target as high as $69, the recent performance and negative earnings reports suggest that risks outweigh potential rewards. The main risk is the company's ongoing losses, with a net income of -11,729,656 USD in Q2 2026, indicating financial instability.

Valuation Metrics

The current forward P/E ratio for ProMIS Neurosciences Inc (PMN) is 0.00, compared to its 5-year average forward P/E of -1.33.

Forward P/E

Fair
5Y Average P/E
-1.33
Current P/E
0.00
Overvalued
0.39
Undervalued
-3.05

Forward EV/EBITDA

Overvalued
5Y Average EV/EBITDA
-1.37
Current EV/EBITDA
0.00
Overvalued
-0.40
Undervalued
-2.34

Forward P/S

Fair
5Y Average P/S
2573.22
Current P/S
0.00
Overvalued
7268.82
Undervalued
-2122.38

Alphio AI Price Scenarios for PMN

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%PMN

$0.45

Scenario price

B

Base

Base · 50%PMN

$0.44

Scenario price

B

Bear

Bear · 25%PMN

$0.40

Scenario price

Whales holding PMN

D

Deep Track Capital, LP

+ HoldingPMN

+24.27%

3M Return

Events Timeline

2026-10-30 (ET)

12:30:00

Promis Neurosciences Inc Trading Halted

2026-10-06 (ET)

07:30:00

ProMIS Neurosciences Appoints Ivana Rubino as Chief Commercial Officer

2026-08-13 (ET)

16:30:00

ProMIS Ends Q2 with $53.4 Million in Cash

2026-07-28 (ET)

06:30:00

ProMIS Neurosciences Reports Positive Interim Results for PMN310 Trial

2026-07-14 (ET)

06:03:00

ProMIS PMN310 Shows Dose-Dependent AbetaO Reduction at 3 and 29 Days at AAIC 2026

News

PMN FAQ — answered by Alphio AI

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

ProMIS Neurosciences Inc is not a good buy right now due to its extremely low RSI of 20.628, indicating oversold conditions, and a staggering 5-day price change of -62.78%. The stock is currently trading at $3.00, significantly below its 52-week high of $27.40, which raises concerns about its viability. While analysts have set a price target as high as $69, the recent performance and negative earnings reports suggest that risks outweigh potential rewards. The main risk is the company's ongoing losses, with a net income of -11,729,656 USD in Q2 2026, indicating financial instability.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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