Protalix Biotherapeutics Inc

Protalix Biotherapeutics Inc (PLX) Stock Analysis

$2.690

+0.083 (+3.07%)At close

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High
2.730
Open
2.610
VWAP
2.67
Volume
870.83K
Mkt Cap
94.58M
Low
2.580
Amount
2.32M
EV/EBITDA, TTM
11.18

Protalix BioTherapeutics, Inc. is a biopharmaceutical company. The Company is focused on the development and commercialization of recombinant therapeutic proteins expressed through its proprietary plant cell-based expression system, ProCellEx. In addition, the Company is developing PEGylated uricase, or PRX-115, for the treatment of uncontrolled gout, Long Acting (LA) DNase I, or PRX-119, for the treatment of NETs-related diseases, and other technologies and preclinical assets. Its ProCellEx platform is being used to manufacture both of its approved and marketed products as well as PRX-115 and PRX-119. PRX-115, a plant cell-expressed recombinant PEGylated Uricase (urate oxidase) - a chemically modified enzyme to treat uncontrolled gout. PRX-119 is a plant cell-expressed PEGylated recombinant human DNase I product candidate. Its product includes Elelyso and Elfabrio. Elelyso is an enzyme replacement therapy (ERT) for the treatment of patients with Gaucher disease.

protalix.com

AI analysis of Protalix Biotherapeutics Inc (PLX)

Buy

Protalix Biotherapeutics Inc is a good buy right now due to its strong recent earnings report showing a net income of $18.3 million for Q1 2026, translating to an EPS of $0.22, which is a significant improvement from the previous year's loss. Additionally, the company has reaffirmed its revenue guidance for 2026, projecting total revenues between $78 million and $83 million, which further supports investor confidence. However, the current RSI of 43.51 indicates that the stock is approaching oversold territory, which could present a buying opportunity. The main risk is the forward P/E ratio of 51.81, suggesting that the stock may be overvalued if growth does not materialize as expected.

Analyst Ratings (2)

+346.10% upside
Buy
2 Buy
0 Hold
0 Sell
Current: 2.69
Low
12.00
Average
12.00
High
12.00

Morgan Stanley

2025-12-16

Price Target

—

Equal Weight

JPMorgan

2025-12-02

Price Target

—

Neutral

H.C. Wainwright

2025-11-21

Price Target

$12

Buy

HC Wainwright & Co.

2025-02-03

Price Target

$15

Strong Buy

HC Wainwright & Co.

2023-11-14

Price Target

$10

Strong Buy

Valuation Metrics

The current forward P/E ratio for Protalix Biotherapeutics Inc (PLX) is 51.28, compared to its 5-year average forward P/E of 9.31.

Forward P/E

Strongly Overvalued
5Y Average P/E
9.31
Current P/E
51.28
Overvalued
25.52
Undervalued
-6.90

Forward EV/EBITDA

Overvalued
5Y Average EV/EBITDA
-0.55
Current EV/EBITDA
11.18
Overvalued
6.04
Undervalued
-7.13

Forward P/S

Overvalued
5Y Average P/S
1.86
Current P/S
3.16
Overvalued
2.60
Undervalued
1.11

Events Timeline

2026-01-30 (ET)

10:00:00

Chiesi and Protalix Update on Elfabrio Progress

2025-12-17 (ET)

07:00:00

Protalix and Secarna Collaborate on Rare Renal Disease Therapies

2025-11-13 (ET)

06:54:47

Protalix Announces Q3 Earnings Per Share of 3 Cents, Below Consensus Estimate of 5 Cents

2025-10-17 (ET)

07:05:41

Protalix and Chiesi Global Receive Negative CHMP Opinion for Elfabrio

2025-07-21 (ET)

06:52:09

Protalix appoints Gilad Mamlok as CFO

News

PLX FAQ — answered by Alphio AI

Protalix BioTherapeutics, Inc. is a biopharmaceutical company. The Company is focused on the development and commercialization of recombinant therapeutic proteins expressed through its proprietary plant cell-based expression system, ProCellEx. In addition, the Company is developing PEGylated uricase, or PRX-115, for the treatment of uncontrolled gout, Long Acting (LA) DNase I, or PRX-119, for the treatment of NETs-related diseases, and other technologies and preclinical assets. Its ProCellEx platform is being used to manufacture both of its approved and marketed products as well as PRX-115 and PRX-119. PRX-115, a plant cell-expressed recombinant PEGylated Uricase (urate oxidase) - a chemically modified enzyme to treat uncontrolled gout. PRX-119 is a plant cell-expressed PEGylated recombinant human DNase I product candidate. Its product includes Elelyso and Elfabrio. Elelyso is an enzyme replacement therapy (ERT) for the treatment of patients with Gaucher disease. It operates in the Healthcare sector (BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES) industry).

Protalix Biotherapeutics Inc is a good buy right now due to its strong recent earnings report showing a net income of $18.3 million for Q1 2026, translating to an EPS of $0.22, which is a significant improvement from the previous year's loss. Additionally, the company has reaffirmed its revenue guidance for 2026, projecting total revenues between $78 million and $83 million, which further supports investor confidence. However, the current RSI of 43.51 indicates that the stock is approaching oversold territory, which could present a buying opportunity. The main risk is the forward P/E ratio of 51.81, suggesting that the stock may be overvalued if growth does not materialize as expected.

2 analysts cover PLX: 2 rate it Buy, 0 Hold and 0 Sell. The average price target is 12.00.

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