Onkure Therapeutics Inc

Onkure Therapeutics Inc (OKUR) Stock Analysis

$2.525

-0.063 (-2.51%)At close

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High
2.580
Open
2.540
VWAP
2.47
Volume
325.17K
Mkt Cap
—
Low
2.315
Amount
804.25K
EV/EBITDA, TTM
0.00

OnKure Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the discovery and development of precision medicines that target biologically validated drivers of cancers that are underserved by available therapies. Using a structure-based drug design platform, the Company is building a pipeline of tumor-agnostic candidates. It is developing OKI-219, a selective PI3KaH1047R inhibitor, as its lead program. It is engaged in targeting oncogenic PI3Ka and has multiple programs designed to enable targeting of this key oncogene. It is focused on delivering highly selective drug candidates that preserve wild-type PI3Ka while targeting the PI3Ka-mutated cancers, initially in advanced breast cancer. Its lead product candidate, OKI-219, is advancing in a phase I clinical trial. It also focuses on a development candidate targeting the most common PI3Ka mutations, such as H1047R, E545K, and E542K. Additionally, it is developing an allosteric inhibitor molecule.

AI analysis of Onkure Therapeutics Inc (OKUR)

Buy

Onkure Therapeutics Inc is a good buy right now due to its current price of $2.59, which is significantly below its 52-week high of $5.38, indicating potential for upside. Additionally, the RSI is at 60, suggesting that the stock is nearing overbought conditions but still has room to grow. The recent financing of $150 million strengthens its cash position, allowing for continued R&D, which is critical for long-term growth. However, the main risk is the negative earnings trend, with a reported EPS of -1.11 last quarter, missing expectations by $0.37, which could affect investor sentiment.

Valuation Metrics

The current forward P/E ratio for Onkure Therapeutics Inc (OKUR) is 0.00, compared to its 5-year average forward P/E of -1.49.

Forward P/E

Fair
5Y Average P/E
-1.49
Current P/E
0.00
Overvalued
0.30
Undervalued
-3.28

Forward EV/EBITDA

Strongly Undervalued
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued
0.00
Undervalued
0.00

Forward P/S

Fair
5Y Average P/S
101.54
Current P/S
157.33
Overvalued
207.68
Undervalued
-4.60

Alphio AI Price Scenarios for OKUR

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%OKUR

$2.65

Scenario price

B

Base

Base · 50%OKUR

$2.61

Scenario price

B

Bear

Bear · 25%OKUR

$2.20

Scenario price

Whales holding OKUR

S

Sofinnova Investments, Inc.

+ HoldingOKUR

+30.18%

3M Return

B

BVF Partners L.P.

+ HoldingOKUR

+8.72%

3M Return

A

ADAR1 Capital Management, LLC

+ HoldingOKUR

+0.28%

3M Return

S

StepStone Group Inc.

+ HoldingOKUR

-0.27%

3M Return

Events Timeline

2026-11-04 (ET)

17:31:00

OnKure Plans IND Submissions for 2027

2026-08-04 (ET)

16:30:00

OnKure Advances PI3Kalpha Inhibitor Development, Plans IND Submission in 2027

2026-05-05 (ET)

16:40:00

OnKure Focuses on PI3Kalpha New Drug Development

2026-04-24 (ET)

16:10:00

OnKure Therapeutics Files to Sell 36.14M Shares of Class A Common

2026-03-27 (ET)

08:20:00

OnKure Therapeutics Completes $150M Private Placement

News

OKUR FAQ — answered by Alphio AI

OnKure Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the discovery and development of precision medicines that target biologically validated drivers of cancers that are underserved by available therapies. Using a structure-based drug design platform, the Company is building a pipeline of tumor-agnostic candidates. It is developing OKI-219, a selective PI3KaH1047R inhibitor, as its lead program. It is engaged in targeting oncogenic PI3Ka and has multiple programs designed to enable targeting of this key oncogene. It is focused on delivering highly selective drug candidates that preserve wild-type PI3Ka while targeting the PI3Ka-mutated cancers, initially in advanced breast cancer. Its lead product candidate, OKI-219, is advancing in a phase I clinical trial. It also focuses on a development candidate targeting the most common PI3Ka mutations, such as H1047R, E545K, and E542K. Additionally, it is developing an allosteric inhibitor molecule. It operates in the Healthcare sector.

Onkure Therapeutics Inc is a good buy right now due to its current price of $2.59, which is significantly below its 52-week high of $5.38, indicating potential for upside. Additionally, the RSI is at 60, suggesting that the stock is nearing overbought conditions but still has room to grow. The recent financing of $150 million strengthens its cash position, allowing for continued R&D, which is critical for long-term growth. However, the main risk is the negative earnings trend, with a reported EPS of -1.11 last quarter, missing expectations by $0.37, which could affect investor sentiment.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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