Mereo BioPharma Group PLC

Mereo BioPharma Group PLC (MREO) Stock Analysis

$0.277

+0.010 (+3.71%)At close

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High
0.288
Open
0.270
VWAP
0.28
Vol
1.56M
Mkt Cap
531.76M
Low
0.270
Amount
433.61K
EV/EBITDA, TTM
0.00

Mereo BioPharma Group plc is a biopharmaceutical company focused on the development of therapeutics for rare diseases. The Company has developed a portfolio of late-stage clinical product candidates, and its two rare disease product candidates are setrusumab for the treatment of osteogenesis imperfecta (OI) and alvelestat primarily for the treatment of severe alpha-1 antitrypsin deficiency-associated lung disease (AATD-LD). In addition to the rare disease programs, it has two oncology product candidates in clinical development, which include Etigilimab, an IgG1 monoclonal antibody which binds to the human T-cell immunoreceptor with Ig and ITIM domains (TIGIT) receptor on immune cells to improve the activation and effectiveness of T-cell and NK cell antitumor activity and Navicixizumab is a bispecific antibody that inhibits delta-like ligand 4 (DLL4) and vascular endothelial growth factor (VEGF). Navicixizumab is developed for the treatment of late-line ovarian cancer.

AI analysis of Mereo BioPharma Group PLC (MREO)

sell

Mereo BioPharma is not a good buy right now. The current price is $0.2525, and the stock has experienced a significant decline of 85.73% over the past year. Additionally, the RSI is at a very low 15.36, indicating oversold conditions, but this could signal further downside risk rather than a buying opportunity. The downgrade from JP Morgan highlights regulatory uncertainties that could hinder future performance, making it a risky investment at this time.

Valuation Metrics

The current forward P/E ratio for Mereo BioPharma Group PLC (MREO) is 0.00, compared to its 5-year average forward P/E of -83.25.

Forward P/E

Fair
5Y Average P/E
-83.25
Current P/E
0.00
Overvalued
22.22
Undervalued
-188.71

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-0.61
Current EV/EBITDA
0.00
Overvalued
5.46
Undervalued
-6.67

Forward P/S

Fair
5Y Average P/S
9.83
Current P/S
2.80
Overvalued
19.14
Undervalued
0.53

Alphio AI Price Scenarios for MREO

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%MREO

$1.93

Scenario price

B

Base

Base · 50%MREO

$1.89

Scenario price

B

Bear

Bear · 25%MREO

$1.80

Scenario price

Whales holding MREO

E

EcoR1 Capital, LLC

+ HoldingMREO

+28.25%

3M Return

Events Timeline

2026-08-11 (ET)

08:30:00

Mereo BioPharma Partners with Sentynl Therapeutics to Advance AATD-LD Study

08:30:00

Mereo BioPharma Signs License Agreement with Sentynl for Alvelestat

2026-05-12 (ET)

07:50:00

Mereo Engages Regulatory Agencies on Setrusumab with Ultragenyx

2026-03-19 (ET)

08:40:00

Company Cash and Cash Equivalents Drop to $41 Million

08:40:00

Denise Scots-Knight: Q4 Revenue $500,000

News

MREO FAQ — answered by Alphio AI

Mereo BioPharma Group plc is a biopharmaceutical company focused on the development of therapeutics for rare diseases. The Company has developed a portfolio of late-stage clinical product candidates, and its two rare disease product candidates are setrusumab for the treatment of osteogenesis imperfecta (OI) and alvelestat primarily for the treatment of severe alpha-1 antitrypsin deficiency-associated lung disease (AATD-LD). In addition to the rare disease programs, it has two oncology product candidates in clinical development, which include Etigilimab, an IgG1 monoclonal antibody which binds to the human T-cell immunoreceptor with Ig and ITIM domains (TIGIT) receptor on immune cells to improve the activation and effectiveness of T-cell and NK cell antitumor activity and Navicixizumab is a bispecific antibody that inhibits delta-like ligand 4 (DLL4) and vascular endothelial growth factor (VEGF). Navicixizumab is developed for the treatment of late-line ovarian cancer. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Mereo BioPharma is not a good buy right now. The current price is $0.2525, and the stock has experienced a significant decline of 85.73% over the past year. Additionally, the RSI is at a very low 15.36, indicating oversold conditions, but this could signal further downside risk rather than a buying opportunity. The downgrade from JP Morgan highlights regulatory uncertainties that could hinder future performance, making it a risky investment at this time.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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