MacroGenics Inc

MacroGenics Inc (MGNX) Stock Analysis

$2.220

-0.087 (-3.90%)At close

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High
2.334
Open
2.300
VWAP
2.25
Volume
1.30M
Mkt Cap
258.05M
Low
2.205
Amount
2.93M
EV/EBITDA, TTM
-2.15

MacroGenics, Inc. is a biopharmaceutical company. The Company is focused on developing antibody-based therapeutics for the treatment of cancer. The Company generates its pipeline of product candidates from its proprietary suite of antibody technology platforms. It is developing therapeutics utilizing multiple modalities, including antibody-drug conjugates (ADCs) and multi-specific antibodies (which are referred to as DART and TRIDENT molecules). It has multiple proprietary product candidates. These include three clinical-stage ADCs incorporating a novel topoisomerase I inhibitor (TOP1i)-based linker-payload: MGC026, which targets B7-H3; MGC028, which targets ADAM9, and MGC030, which is directed against an undisclosed target. It is also developing lorigerlimab, a clinical-stage bispecific DART molecule targeting the immune checkpoint receptors PD-1 and CTLA-4. In addition, it is also developing multiple preclinical-stage ADC and next-generation T-cell engager programs.

AI analysis of MacroGenics Inc (MGNX)

Hold

MacroGenics Inc is currently trading at $2.33, which is significantly below its 52-week high of $5.08, indicating potential upside. However, the RSI is at a low 27.43, suggesting the stock is oversold, but the forward P/E ratio is very high at 60.98, indicating potential overvaluation. The main risk is the high debt-to-equity ratio of 415.52%, which raises concerns about financial stability.

Analyst Ratings (11)

+35.14% upside
Buy
9 Buy
2 Hold
0 Sell
Current: 2.22
Low
2.00
Average
3.00
High
4.00

Barclays

2026-04-20

Price Target

$6

Overweight

B. Riley

2026-04-10

Price Target

$9

Buy

Barclays

2026-03-10

Price Target

$4

Overweight

Barclays

2025-09-16

Price Target

$3

Overweight

B. Riley

2025-05-20

Price Target

$3

Neutral

Valuation Metrics

The current forward P/E ratio for MacroGenics Inc (MGNX) is 60.98, compared to its 5-year average forward P/E of 7.89.

Forward P/E

Strongly Overvalued
5Y Average P/E
7.89
Current P/E
60.98
Overvalued
30.66
Undervalued
-14.87

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-2.48
Current EV/EBITDA
-2.15
Overvalued
0.46
Undervalued
-5.43

Forward P/S

Fair
5Y Average P/S
3.13
Current P/S
1.64
Overvalued
5.19
Undervalued
1.07

Alphio AI Price Scenarios for MGNX

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%MGNX

$3.78

Scenario price

B

Base

Base · 50%MGNX

$3.06

Scenario price

B

Bear

Bear · 25%MGNX

$1.69

Scenario price

Whales holding MGNX

A

Armistice Capital LLC

+ HoldingMGNX

+31.42%

3M Return

Events Timeline

2026-11-05 (ET)

14:00:00

Shield AI Acquires Radar Company for $5.3 Billion

2026-10-26 (ET)

07:30:00

MacroGenics Reports Interim Data from Phase 2 Study of Lorigerlimab

2026-10-23 (ET)

09:30:00

MacroGenics Reports MGC026 Clinical Data Showing Antitumor Activity

2026-10-15 (ET)

16:30:00

MacroGenics Doses First Patient in Phase 1 Study of MGC030

2026-08-13 (ET)

16:30:00

MacroGenics Reports Q2 Revenue of $32.83M

News

MGNX FAQ — answered by Alphio AI

MacroGenics, Inc. is a biopharmaceutical company. The Company is focused on developing antibody-based therapeutics for the treatment of cancer. The Company generates its pipeline of product candidates from its proprietary suite of antibody technology platforms. It is developing therapeutics utilizing multiple modalities, including antibody-drug conjugates (ADCs) and multi-specific antibodies (which are referred to as DART and TRIDENT molecules). It has multiple proprietary product candidates. These include three clinical-stage ADCs incorporating a novel topoisomerase I inhibitor (TOP1i)-based linker-payload: MGC026, which targets B7-H3; MGC028, which targets ADAM9, and MGC030, which is directed against an undisclosed target. It is also developing lorigerlimab, a clinical-stage bispecific DART molecule targeting the immune checkpoint receptors PD-1 and CTLA-4. In addition, it is also developing multiple preclinical-stage ADC and next-generation T-cell engager programs. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

MacroGenics Inc is currently trading at $2.33, which is significantly below its 52-week high of $5.08, indicating potential upside. However, the RSI is at a low 27.43, suggesting the stock is oversold, but the forward P/E ratio is very high at 60.98, indicating potential overvaluation. The main risk is the high debt-to-equity ratio of 415.52%, which raises concerns about financial stability.

11 analysts cover MGNX: 9 rate it Buy, 2 Hold and 0 Sell. The average price target is 3.00.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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