Lexeo Therapeutics Inc

Lexeo Therapeutics Inc (LXEO) Stock Analysis

$3.230

+0.125 (+3.86%)At close

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High
3.440
Open
3.220
VWAP
3.24
Volume
1.19M
Mkt Cap
—
Low
3.035
Amount
3.85M
EV/EBITDA, TTM
0.00

Lexeo Therapeutics, Inc. is a clinical-stage genetic medicine company dedicated to transforming healthcare by applying pioneering science to fundamentally change how genetically defined cardiovascular diseases and APOE4-associated Alzheimers disease are treated. Using a stepwise development approach, the Company is leveraging early proof-of-concept functional and biomarker data to advance a pipeline of cardiovascular and APOE4-associated Alzheimers disease programs. Its pipeline consists of candidates targeting patient populations. Its most advanced cardiovascular product candidate, LX2006 for the treatment of patients with Friedreichs ataxia (FA), cardiomyopathy, is being evaluated in SUNRISE-FA, an ongoing Phase I/II clinical trial. Its second most advanced cardiovascular product candidate, LX2020 for the treatment of arrhythmogenic cardiomyopathy, caused by mutations in the PKP2 gene (PKP2-ACM), received IND clearance from the United States Food and Drug Administration (FDA).

AI analysis of Lexeo Therapeutics Inc (LXEO)

Hold

Lexeo Therapeutics Inc is currently not a strong buy. The stock is priced at $3.06, significantly below its 52-week high of $10.99, indicating a potential for recovery but also substantial risk. The RSI is at 55.25, suggesting that the stock is neither overbought nor oversold, which may indicate a stable trend. However, the forward P/E ratio is 5.66, which is low, but the company has been consistently reporting negative net income, with a net loss of $25.9 million in Q4 2024 and a gross profit of $0 in that same quarter. The recent insider selling has increased by 271.82%, which raises concerns about insider confidence. The main risk is the ongoing losses, as evidenced by a projected EPS of -0.33 for the next earnings report on November 4, 2026.

Valuation Metrics

The current forward P/E ratio for Lexeo Therapeutics Inc (LXEO) is 5.54, compared to its 5-year average forward P/E of -2.95.

Forward P/E

Strongly Overvalued
5Y Average P/E
-2.95
Current P/E
5.54
Overvalued
0.40
Undervalued
-6.30

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-2.06
Current EV/EBITDA
0.00
Overvalued
0.38
Undervalued
-4.50

Forward P/S

Fair
5Y Average P/S
12.03
Current P/S
0.00
Overvalued
34.68
Undervalued
-10.63

Alphio AI Price Scenarios for LXEO

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%LXEO

$4.36

Scenario price

B

Base

Base · 50%LXEO

$4.02

Scenario price

B

Bear

Bear · 25%LXEO

$3.70

Scenario price

Whales holding LXEO

P

Paradigm Biocapital Advisors LP

+ HoldingLXEO

+3.90%

3M Return

S

Suvretta Capital Management, LLC

+ HoldingLXEO

-4.47%

3M Return

F

Frazier Life Sciences Management, LP

+ HoldingLXEO

-8.39%

3M Return

A

Avoro Capital Advisors LLC

+ HoldingLXEO

-8.49%

3M Return

V

Vestal Point Capital, LP

+ HoldingLXEO

-14.26%

3M Return

LXEO FAQ — answered by Alphio AI

Lexeo Therapeutics, Inc. is a clinical-stage genetic medicine company dedicated to transforming healthcare by applying pioneering science to fundamentally change how genetically defined cardiovascular diseases and APOE4-associated Alzheimers disease are treated. Using a stepwise development approach, the Company is leveraging early proof-of-concept functional and biomarker data to advance a pipeline of cardiovascular and APOE4-associated Alzheimers disease programs. Its pipeline consists of candidates targeting patient populations. Its most advanced cardiovascular product candidate, LX2006 for the treatment of patients with Friedreichs ataxia (FA), cardiomyopathy, is being evaluated in SUNRISE-FA, an ongoing Phase I/II clinical trial. Its second most advanced cardiovascular product candidate, LX2020 for the treatment of arrhythmogenic cardiomyopathy, caused by mutations in the PKP2 gene (PKP2-ACM), received IND clearance from the United States Food and Drug Administration (FDA). It operates in the Healthcare sector (BIOLOGICAL PRODUCTS, EXCEPT DIAGNOSTIC SUBSTANCES industry).

Lexeo Therapeutics Inc is currently not a strong buy. The stock is priced at $3.06, significantly below its 52-week high of $10.99, indicating a potential for recovery but also substantial risk. The RSI is at 55.25, suggesting that the stock is neither overbought nor oversold, which may indicate a stable trend. However, the forward P/E ratio is 5.66, which is low, but the company has been consistently reporting negative net income, with a net loss of $25.9 million in Q4 2024 and a gross profit of $0 in that same quarter. The recent insider selling has increased by 271.82%, which raises concerns about insider confidence. The main risk is the ongoing losses, as evidenced by a projected EPS of -0.33 for the next earnings report on November 4, 2026.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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