Werewolf Therapeutics Inc

Werewolf Therapeutics Inc (HOWL) Stock Analysis

$1.003

-0.017 (-1.71%)At close

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High
1.030
Open
1.020
VWAP
1.01
Volume
176.49K
Mkt Cap
109.07M
Low
0.983
Amount
177.39K
EV/EBITDA, TTM
0.00

Werewolf Therapeutics, Inc. is a biopharmaceutical company engaged in the development of therapeutics engineered to stimulate the body’s immune system for the treatment of cancer and other immune-mediated conditions. It is leveraging its PREDATOR platform to design conditionally activated molecules that stimulate both adaptive and innate immunity with the goal of addressing the limitations of conventional proinflammatory immune therapies. Its INDUKINE molecules are intended to remain inactive in peripheral tissue yet activate selectively in the tumor microenvironment. The Company’s advanced clinical-stage product candidates, WTX-124 and WTX-330, are systemically delivered, conditionally activated Interleukin-2 (IL-2) and IL-12 INDUKINE molecules for the treatment of solid tumors. It is advancing WTX-124 in multiple tumor types as a single agent and in combination with an immune checkpoint inhibitor. It is advancing WTX-712, WTX-518, and WTX-921 through preclinical development.

AI analysis of Werewolf Therapeutics Inc (HOWL)

Buy

Werewolf Therapeutics Inc is a good buy right now due to its recent financial turnaround, evidenced by a Q2 net profit of $3.67 million, which is a significant improvement from a loss of $17.98 million in the same quarter last year. Additionally, the stock has shown a strong year-to-date performance with a 62.84% increase, and it is currently trading at $1.05, which is 75.7% of its 52-week range. The upcoming earnings report on November 3, 2026, could further boost investor confidence if positive results are announced, although insider selling has increased by 194.65%, which is a potential risk.

Valuation Metrics

The current forward P/E ratio for Werewolf Therapeutics Inc (HOWL) is 0.00, compared to its 5-year average forward P/E of -2.07.

Forward P/E

Overvalued
5Y Average P/E
-2.07
Current P/E
0.00
Overvalued
-0.66
Undervalued
-3.48

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-0.35
Current EV/EBITDA
0.00
Overvalued
0.76
Undervalued
-1.46

Forward P/S

Fair
5Y Average P/S
24.06
Current P/S
0.00
Overvalued
50.28
Undervalued
-2.16

Events Timeline

2026-08-21 (ET)

09:00:00

Stock Futures Rise as Investors Seek Recovery

08:30:00

Werewolf Therapeutics and Ambros Therapeutics Enter Merger Agreement

2026-03-27 (ET)

07:20:00

Werewolf Cash and Cash Equivalents Drop to $57.1M

07:20:00

Werewolf Therapeutics Engages Piper Sandler for Strategic Evaluation

07:10:00

Werewolf Therapeutics to Explore Range of Strategic Alternatives

News

HOWL FAQ — answered by Alphio AI

Werewolf Therapeutics, Inc. is a biopharmaceutical company engaged in the development of therapeutics engineered to stimulate the body’s immune system for the treatment of cancer and other immune-mediated conditions. It is leveraging its PREDATOR platform to design conditionally activated molecules that stimulate both adaptive and innate immunity with the goal of addressing the limitations of conventional proinflammatory immune therapies. Its INDUKINE molecules are intended to remain inactive in peripheral tissue yet activate selectively in the tumor microenvironment. The Company’s advanced clinical-stage product candidates, WTX-124 and WTX-330, are systemically delivered, conditionally activated Interleukin-2 (IL-2) and IL-12 INDUKINE molecules for the treatment of solid tumors. It is advancing WTX-124 in multiple tumor types as a single agent and in combination with an immune checkpoint inhibitor. It is advancing WTX-712, WTX-518, and WTX-921 through preclinical development. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Werewolf Therapeutics Inc is a good buy right now due to its recent financial turnaround, evidenced by a Q2 net profit of $3.67 million, which is a significant improvement from a loss of $17.98 million in the same quarter last year. Additionally, the stock has shown a strong year-to-date performance with a 62.84% increase, and it is currently trading at $1.05, which is 75.7% of its 52-week range. The upcoming earnings report on November 3, 2026, could further boost investor confidence if positive results are announced, although insider selling has increased by 194.65%, which is a potential risk.

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