Fractyl Health Inc

Fractyl Health Inc (GUTS) Stock Analysis

$0.930

+0.035 (+3.81%)At close

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High
0.948
Open
0.883
VWAP
0.92
Volume
85.31K
Mkt Cap
—
Low
0.883
Amount
78.51K
EV/EBITDA, TTM
0.00

Fractyl Health, Inc. is a metabolic therapeutics company. The Company is focused on developing new approaches to the treatment of metabolic diseases, including obesity and type 2 diabetes (T2D). The Company’s lead product candidate, Revita, is designed to remodel the duodenal lining via hydrothermal ablation (i.e. duodenal mucosal resurfacing) to reverse damage to intestinal nutrient sensing and signaling mechanisms caused by chronic high-fat and high-sugar diets that are a root cause of metabolic disease. The Revita clinical program is focused on patients living with obesity who want to maintain their weight loss after GLP-1 drug discontinuation. The Company’s Rejuva platform focuses on developing adeno-associated virus (AAV)-based, locally delivered gene therapies for the treatment of obesity and T2D. The Rejuva platform leverages advanced delivery systems and proprietary screening methods to identify and develop metabolically active gene therapy candidates targeting the pancreas.

AI analysis of Fractyl Health Inc (GUTS)

Hold

Fractyl Health Inc (GUTS) is currently not a good buy due to its very low current price of $0.93, which is significantly below its 52-week high of $29.34, indicating a severe decline of 96.56% year-to-date. The RSI is at 25.036, suggesting the stock is oversold, but the lack of revenue and the negative earnings per share (EPS) of -1.5900 for the upcoming earnings report raises concerns. The main risk is the company's substantial net income loss of -25,538,000 USD in Q2 2026, which could further impact its financial stability.

Valuation Metrics

The current forward P/E ratio for Fractyl Health Inc (GUTS) is 0.00, compared to its 5-year average forward P/E of -1.93.

Forward P/E

Overvalued
5Y Average P/E
-1.93
Current P/E
0.00
Overvalued
-0.62
Undervalued
-3.24

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-2.24
Current EV/EBITDA
0.00
Overvalued
0.18
Undervalued
-4.66

Forward P/S

Fair
5Y Average P/S
3368.95
Current P/S
9.14
Overvalued
8281.16
Undervalued
-1543.25

Alphio AI Price Scenarios for GUTS

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%GUTS

$2.04

Scenario price

B

Base

Base · 50%GUTS

$1.81

Scenario price

B

Bear

Bear · 25%GUTS

$1.50

Scenario price

Whales holding GUTS

P

Pale Fire Capital SE

+ HoldingGUTS

+0.00%

3M Return

Events Timeline

2026-10-22 (ET)

09:30:00

Fractyl Health Focuses on Revita, Cuts 45% of Workforce

09:30:00

Fractyl Health Co-Founder Jay Caplan to Retire on October 30

09:30:00

Fractyl Health Discontinues Rejuva Gene Therapy Development

2026-10-16 (ET)

07:30:00

Fractyl Health Reports Six-Month Results from REMAIN-1 Study

2026-08-10 (ET)

17:00:00

Fractyl CEO: Revita Procedure Significantly Reduces Weight Regain

News

GUTS FAQ — answered by Alphio AI

Fractyl Health, Inc. is a metabolic therapeutics company. The Company is focused on developing new approaches to the treatment of metabolic diseases, including obesity and type 2 diabetes (T2D). The Company’s lead product candidate, Revita, is designed to remodel the duodenal lining via hydrothermal ablation (i.e. duodenal mucosal resurfacing) to reverse damage to intestinal nutrient sensing and signaling mechanisms caused by chronic high-fat and high-sugar diets that are a root cause of metabolic disease. The Revita clinical program is focused on patients living with obesity who want to maintain their weight loss after GLP-1 drug discontinuation. The Company’s Rejuva platform focuses on developing adeno-associated virus (AAV)-based, locally delivered gene therapies for the treatment of obesity and T2D. The Rejuva platform leverages advanced delivery systems and proprietary screening methods to identify and develop metabolically active gene therapy candidates targeting the pancreas. It operates in the Healthcare sector (SURGICAL AND MEDICAL INSTRUMENTS AND APPARATUS industry).

Fractyl Health Inc (GUTS) is currently not a good buy due to its very low current price of $0.93, which is significantly below its 52-week high of $29.34, indicating a severe decline of 96.56% year-to-date. The RSI is at 25.036, suggesting the stock is oversold, but the lack of revenue and the negative earnings per share (EPS) of -1.5900 for the upcoming earnings report raises concerns. The main risk is the company's substantial net income loss of -25,538,000 USD in Q2 2026, which could further impact its financial stability.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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