Ensysce Biosciences Inc

Ensysce Biosciences Inc (ENSC) Stock Analysis

$0.338

-0.022 (-6.48%)At close

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High
0.361
Open
0.360
VWAP
0.33
Volume
430.27K
Mkt Cap
4.06M
Low
0.301
Amount
143.38K
EV/EBITDA, TTM
-0.99

Ensysce Biosciences, Inc. is a clinical-stage pharmaceutical company. It develops solutions for severe pain relief while reducing the potential for opioid misuse, abuse, and overdose. Its pipeline includes an abuse-resistant opioid prodrug technology, the Trypsin Activated Abuse Protection (TAAP) platform, and an over-dose protection opioid prodrug technology, the Multi-Pill Abuse Resistant (MPAR) platform. Its lead product, PF614, is a TAAP extended-release oxycodone and a potential analgesic to treat severe pain. Its second product, PF614-MPAR, is to treat severe pain with the added benefit of oral overdose protection, is a combination product of the TAAP prodrug PF614 with a trypsin inhibitor. Additionally, nafamostat, which is an ingredient in its overdose protection combination products, is also being developed for the intended purpose of treating infection and pulmonary lung diseases. It is also developing novel neuroplastogenic therapies for complex regional pain syndrome.

ensysce.com

AI analysis of Ensysce Biosciences Inc (ENSC)

Sell

Ensysce Biosciences Inc is not a good buy right now. The current price is $0.34, and the stock has experienced a significant decline of 64.09% year-to-date. Additionally, the RSI is at a very low 9.06, indicating extreme oversold conditions, which typically suggests a potential for a rebound but also reflects severe weakness in market sentiment. The main risk is the company's negative earnings trend, with an EPS of -0.20 expected for the next quarter, which could further pressure the stock price.

Valuation Metrics

The current forward P/E ratio for Ensysce Biosciences Inc (ENSC) is 0.95, compared to its 5-year average forward P/E of -0.61.

Forward P/E

Overvalued
5Y Average P/E
-0.61
Current P/E
0.95
Overvalued
0.60
Undervalued
-1.83

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
30536.45
Current EV/EBITDA
-0.99
Overvalued
209986.21
Undervalued
-148913.31

Forward P/S

Fair
5Y Average P/S
7.91
Current P/S
2.34
Overvalued
18.56
Undervalued
-2.74

Events Timeline

2026-10-23 (ET)

17:00:00

Selling Stockholders Plan to Sell 433.91M Shares of Common Stock

2026-09-24 (ET)

09:00:00

Ensysce Biosciences Submits Phase 2a Study Protocol for CY200

2026-09-14 (ET)

08:30:00

Ensysce Biosciences Executive Attends FDA Hearing on Psychedelic Drugs

2026-08-31 (ET)

09:00:00

Ensysce Biosciences Completes Enrollment in PF614-MPAR-102 Clinical Study

2026-08-06 (ET)

09:00:00

Ensysce Completes Acquisition of Cy Biopharma, Secures $43 Million Financing

News

ENSC FAQ — answered by Alphio AI

Ensysce Biosciences, Inc. is a clinical-stage pharmaceutical company. It develops solutions for severe pain relief while reducing the potential for opioid misuse, abuse, and overdose. Its pipeline includes an abuse-resistant opioid prodrug technology, the Trypsin Activated Abuse Protection (TAAP) platform, and an over-dose protection opioid prodrug technology, the Multi-Pill Abuse Resistant (MPAR) platform. Its lead product, PF614, is a TAAP extended-release oxycodone and a potential analgesic to treat severe pain. Its second product, PF614-MPAR, is to treat severe pain with the added benefit of oral overdose protection, is a combination product of the TAAP prodrug PF614 with a trypsin inhibitor. Additionally, nafamostat, which is an ingredient in its overdose protection combination products, is also being developed for the intended purpose of treating infection and pulmonary lung diseases. It is also developing novel neuroplastogenic therapies for complex regional pain syndrome. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Ensysce Biosciences Inc is not a good buy right now. The current price is $0.34, and the stock has experienced a significant decline of 64.09% year-to-date. Additionally, the RSI is at a very low 9.06, indicating extreme oversold conditions, which typically suggests a potential for a rebound but also reflects severe weakness in market sentiment. The main risk is the company's negative earnings trend, with an EPS of -0.20 expected for the next quarter, which could further pressure the stock price.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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