enGene Therapeutics Inc

enGene Therapeutics Inc (ENGN) Stock Analysis

$1.855

+0.015 (+0.82%)At close

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High
1.870
Open
1.840
VWAP
1.84
Vol
657.38K
Mkt Cap
Low
1.800
Amount
1.21M
EV/EBITDA, TTM
0.00

enGene Therapeutics Inc., formerly enGene Holdings Inc., is a clinical-stage biotechnology company mainstreaming gene therapy through the delivery of therapeutics to mucosal tissues and other organs. The Company’s lead program is detalimogene voraplasmid, (detalimogene) for patients with non-muscle invasive bladder cancer (NMIBC), a disease with a high clinical burden. Detalimogene is being evaluated in the ongoing multi-cohort LEGEND Phase II trial, which includes a pivotal cohort studying detalimogene in Bacillus Calmette-Guerin (BCG)-unresponsive patients with carcinoma in situ (CIS). Detalimogene is being developed through its proprietary Dually Derivatized Oligochitosan (DDX) platform, which enables penetration of mucosal tissues and delivery of a range of sizes and types of cargo, including Deoxyribonucleic acid (DNA) and various forms of Ribonucleic acid (RNA).

engene.com

AI analysis of enGene Therapeutics Inc (ENGN)

hold

enGene Holdings Inc is not a good buy right now due to significant financial losses and analyst downgrades. The current price is $1.825, and the company reported a net loss of $30.23 million for Q2 2026. The forward P/E ratio is 0, indicating no earnings expected in the near term, which raises concerns about its profitability and growth potential.

Valuation Metrics

The current forward P/E ratio for enGene Therapeutics Inc (ENGN) is 0.00, compared to its 5-year average forward P/E of -3.05.

Forward P/E

Overvalued
5Y Average P/E
-3.05
Current P/E
0.00
Overvalued
-0.13
Undervalued
-5.97

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-2.07
Current EV/EBITDA
0.00
Overvalued
1.25
Undervalued
-5.40

Forward P/S

Strongly Overvalued
5Y Average P/S
3.52
Current P/S
19.81
Overvalued
11.27
Undervalued
-4.23

Alphio AI Price Scenarios for ENGN

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%ENGN

$4.68

Scenario price

B

Base

Base · 50%ENGN

$4.26

Scenario price

B

Bear

Bear · 25%ENGN

$3.67

Scenario price

Whales holding ENGN

N

Nextech Invest Ltd.

+ HoldingENGN

+26.68%

3M Return

V

VR Management, LLC

+ HoldingENGN

+15.76%

3M Return

M

MPM BioImpact LLC

+ HoldingENGN

-5.80%

3M Return

Events Timeline

2026-07-16 (ET)

08:30:00

enGene Therapeutics Changes Board Chairman

2026-06-18 (ET)

16:30:00

Major Averages Rebound, Nasdaq Gains 1.91%

12:30:00

Major Averages Rebound, Nasdaq Up 1.28%

2026-06-15 (ET)

16:30:00

Major U.S. Indices Surge on U.S.-Iran Peace Agreement

13:00:00

Major Averages Surge on U.S.-Iran Peace Agreement

News

ENGN FAQ — answered by Alphio AI

enGene Therapeutics Inc., formerly enGene Holdings Inc., is a clinical-stage biotechnology company mainstreaming gene therapy through the delivery of therapeutics to mucosal tissues and other organs. The Company’s lead program is detalimogene voraplasmid, (detalimogene) for patients with non-muscle invasive bladder cancer (NMIBC), a disease with a high clinical burden. Detalimogene is being evaluated in the ongoing multi-cohort LEGEND Phase II trial, which includes a pivotal cohort studying detalimogene in Bacillus Calmette-Guerin (BCG)-unresponsive patients with carcinoma in situ (CIS). Detalimogene is being developed through its proprietary Dually Derivatized Oligochitosan (DDX) platform, which enables penetration of mucosal tissues and delivery of a range of sizes and types of cargo, including Deoxyribonucleic acid (DNA) and various forms of Ribonucleic acid (RNA). It operates in the Healthcare sector.

enGene Holdings Inc is not a good buy right now due to significant financial losses and analyst downgrades. The current price is $1.825, and the company reported a net loss of $30.23 million for Q2 2026. The forward P/E ratio is 0, indicating no earnings expected in the near term, which raises concerns about its profitability and growth potential.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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