Cue Biopharma Inc

Cue Biopharma Inc (CUE) Stock Analysis

$18.010

-1.661 (-9.22%)At close

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High
19.740
Open
19.350
VWAP
18.21
Volume
141.75K
Mkt Cap
68.10M
Low
16.870
Amount
2.58M
EV/EBITDA, TTM
-1.44

Cue Biopharma, Inc. is a clinical-stage biopharmaceutical company, developing a novel class of injectable biologics to selectively engage and modulate disease-specific T cells directly within the patient’s body. Its proprietary platform, Immuno-STAT (Selective Targeting and Alteration of T cells) and biologics are designed to harness the curative potential of the body’s intrinsic immune system through the selective modulation of disease-specific T cells without the adverse effects of broad systemic immune modulation. Its lead programs include drug product candidates designed to: CUE-400 series (Autoimmune Diseases) enhance regulatory T cells (Tregs) with a novel mechanism to proliferate, generate Tregs, and restore immune balance (CUE-401 for autoimmune conditions);CUE-500 series (Targeted Cell Depletion) redirect antiviral T cells to target eliminate pathogenic cells (CUE-501 for autoimmune B cell depletion); and CUE-100 series (Oncology) selectively activate tumor-specific T cells.

AI analysis of Cue Biopharma Inc (CUE)

Buy

Cue Biopharma Inc is a good buy right now due to its recent positive Phase 2a trial results for CUE-221, which showed a 54% complete hive resolution rate compared to 11% for placebo. Additionally, the stock is currently priced at $19.42, significantly below the analyst target of $83, indicating substantial upside potential. However, the company reported a net loss of $153.07 million in Q2 2026, which poses a risk to its financial stability.

Analyst Ratings (1)

Buy
1 Buy
0 Hold
0 Sell
Current: 18.01
Low
—
Average
—
High
—

B. Riley

2026-09-21

Price Target

$83

Buy

B. Riley

2026-09-18

Price Target

$83

Buy

Lucid Capital

2025-08-25

Price Target

$4

Buy

Citizens Capital Markets

2025-04-02

Price Target

$2

Buy

Stifel

2024-08-20

Price Target

$4

Strong Buy

Valuation Metrics

The current forward P/E ratio for Cue Biopharma Inc (CUE) is 0.00, compared to its 5-year average forward P/E of -2.54.

Forward P/E

Overvalued
5Y Average P/E
-2.54
Current P/E
0.00
Overvalued
-1.14
Undervalued
-3.94

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
2.13
Current EV/EBITDA
-1.44
Overvalued
14.68
Undervalued
-10.41

Forward P/S

Fair
5Y Average P/S
44.63
Current P/S
16.65
Overvalued
104.85
Undervalued
-15.58

Whales holding CUE

C

Catalytic Wealth RIA, LLC

+ HoldingCUE

+0.00%

3M Return

Events Timeline

2026-09-20 (ET)

10:30:00

Cue Biopharma Reports Positive Phase 2 Results for CUE-221

2026-08-12 (ET)

16:30:00

Selling Stockholders Plan to Sell 1.5M Shares of Common Stock

2026-08-03 (ET)

09:31:00

Cue Biopharma Appoints James Ahlers as CFO

2026-07-13 (ET)

09:00:00

Cue Biopharma Appoints Dominic Borie as Chief Medical Officer

2026-07-10 (ET)

05:30:00

Cue Biopharma Completes $50 Million Private Placement

News

CUE FAQ — answered by Alphio AI

Cue Biopharma, Inc. is a clinical-stage biopharmaceutical company, developing a novel class of injectable biologics to selectively engage and modulate disease-specific T cells directly within the patient’s body. Its proprietary platform, Immuno-STAT (Selective Targeting and Alteration of T cells) and biologics are designed to harness the curative potential of the body’s intrinsic immune system through the selective modulation of disease-specific T cells without the adverse effects of broad systemic immune modulation. Its lead programs include drug product candidates designed to: CUE-400 series (Autoimmune Diseases) enhance regulatory T cells (Tregs) with a novel mechanism to proliferate, generate Tregs, and restore immune balance (CUE-401 for autoimmune conditions);CUE-500 series (Targeted Cell Depletion) redirect antiviral T cells to target eliminate pathogenic cells (CUE-501 for autoimmune B cell depletion); and CUE-100 series (Oncology) selectively activate tumor-specific T cells. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Cue Biopharma Inc is a good buy right now due to its recent positive Phase 2a trial results for CUE-221, which showed a 54% complete hive resolution rate compared to 11% for placebo. Additionally, the stock is currently priced at $19.42, significantly below the analyst target of $83, indicating substantial upside potential. However, the company reported a net loss of $153.07 million in Q2 2026, which poses a risk to its financial stability.

1 analysts cover CUE: 1 rate it Buy, 0 Hold and 0 Sell.

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