Bicycle Therapeutics PLC (BCYC) Stock Analysis

AI analysis of Bicycle Therapeutics PLC (BCYC)

Hold

Bicycle Therapeutics PLC (BCYC) is currently trading at $3.62, which is significantly below the Oppenheimer price target of $11, suggesting a potential upside of approximately 174%. However, the stock has shown a year-to-date decline of 45.81% and a 52-week range that indicates it is near its low of $3.33. While the gross margin remains strong at 96.8%, the company reported a substantial net loss of $10.48 million in Q3 2026, which is concerning. The RSI of 43.08 indicates the stock is nearing oversold territory, but the overall trend remains bearish. Given these factors, it may be prudent to hold rather than buy at this time, as the risks of further declines are present, especially with a recent earnings miss and declining revenues.

Valuation Metrics

The current forward P/E ratio for Bicycle Therapeutics PLC (BCYC) is 0.00, compared to its 5-year average forward P/E of -5.67.

Forward P/E

Overvalued

5Y Average P/E

-5.67

Current P/E

0.00

Overvalued

-1.89

Undervalued

-9.44

Forward EV/EBITDA

Strongly Undervalued

5Y Average EV/EBITDA

-1.63

Current EV/EBITDA

-101.98

Overvalued

5.54

Undervalued

-8.81

Forward P/S

Fair

5Y Average P/S

37.45

Current P/S

38.48

Overvalued

62.05

Undervalued

12.84

Alphio AI Price Scenarios for BCYC

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%BCYC

$7.67

Scenario price

B

Base

Base · 50%BCYC

$7.15

Scenario price

B

Bear

Bear · 25%BCYC

$6.21

Scenario price

Whales holding BCYC

B

Baker Bros. Advisors LP

+ HoldingBCYC

+12.33%

3M Return

L

Long Focus Capital Management LLC

+ HoldingBCYC

-6.95%

3M Return

BCYC FAQ — answered by Alphio AI

Bicycle Therapeutics plc is a United Kingdom-based clinical-stage biopharmaceutical company developing a class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. The Company is evaluating zelenectide pevedotin, a Bicycle Toxin Conjugate (BTC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BTC targeting EphA2, a historically undruggable target, and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in Company-sponsored clinical trials. Additionally, the Company is developing Bicycle Radio Conjugates (BRC) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle technology to develop therapies for diseases beyond oncology. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Bicycle Therapeutics PLC (BCYC) is currently trading at $3.62, which is significantly below the Oppenheimer price target of $11, suggesting a potential upside of approximately 174%. However, the stock has shown a year-to-date decline of 45.81% and a 52-week range that indicates it is near its low of $3.33. While the gross margin remains strong at 96.8%, the company reported a substantial net loss of $10.48 million in Q3 2026, which is concerning. The RSI of 43.08 indicates the stock is nearing oversold territory, but the overall trend remains bearish. Given these factors, it may be prudent to hold rather than buy at this time, as the risks of further declines are present, especially with a recent earnings miss and declining revenues.