ALX Oncology Holdings Inc

ALX Oncology Holdings Inc (ALXO) Stock Analysis

$1.360

+0.074 (+5.43%)At close

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High
1.400
Open
1.320
VWAP
1.36
Volume
949.51K
Mkt Cap
304.00M
Low
1.320
Amount
1.29M
EV/EBITDA, TTM
0.00

ALX Oncology Holdings Inc. is a clinical-stage biotechnology company advancing a pipeline of therapies designed to treat cancer and extend patients’ lives. The Company's lead product candidate, evorpacept, is a CD47 blocking therapeutic that combines a high-affinity CD47 binding domain with an inactivated, proprietary Fc domain. It is engaged in focusing on combining evorpacept with anti-cancer antibodies, antibody drug conjugate (ADCs), and PD-1/PD-L1 immune checkpoint inhibitors. Evorpacept is being evaluated across multiple ongoing clinical trials in a range of cancer indications. Its second product candidate is ALX2004, an epidermal growth factor receptor (EGFR)-targeted ADC. ALX2004 comprises an affinity-tuned EGFR antibody backbone engineered for optimal activity as an ADC, a proprietary topoisomerase I inhibitor payload with enhanced bystander effect, and a linker with enhanced stability.

AI analysis of ALX Oncology Holdings Inc (ALXO)

Buy

ALX Oncology Holdings Inc is a good buy right now due to its recent price increase of 21.24% over the last five days, indicating strong momentum. The current price of $1.37 is well below its 52-week high of $2.66, suggesting potential for growth. Additionally, the company has sufficient cash reserves of $153.4 million to fund operations through mid-2028, which provides a buffer against financial instability. However, the main risk is the negative earnings trend, with a projected EPS of -0.14 for the upcoming earnings report on November 6, 2026.

Valuation Metrics

The current forward P/E ratio for ALX Oncology Holdings Inc (ALXO) is 0.00, compared to its 5-year average forward P/E of -2.76.

Forward P/E

Fair
5Y Average P/E
-2.76
Current P/E
0.00
Overvalued
0.06
Undervalued
-5.58

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-1.18
Current EV/EBITDA
0.00
Overvalued
1.09
Undervalued
-3.46

Forward P/S

Strongly Undervalued
5Y Average P/S
0.00
Current P/S
0.00
Overvalued
0.00
Undervalued
0.00

Alphio AI Price Scenarios for ALXO

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%ALXO

$0.61

Scenario price

B

Base

Base · 50%ALXO

$0.54

Scenario price

B

Bear

Bear · 25%ALXO

$0.45

Scenario price

Whales holding ALXO

B

Blackstone Alternative Investment Advisors LLC

+ HoldingALXO

-0.88%

3M Return

T

TCG Crossover Management, LLC

+ HoldingALXO

-24.43%

3M Return

Events Timeline

2026-09-28 (ET)

08:30:00

ALX Oncology Publishes ASPEN-06 Clinical Data

2026-06-30 (ET)

08:30:00

ALX Oncology Appoints Scott Garland as Chairman of the Board

2026-04-13 (ET)

09:00:00

ALX Oncology Appoints Jeff Knight as Chief Development and Operating Officer

2026-02-27 (ET)

08:10:00

ALX Oncology CEO: Evorpacept Clinical Trial Data Boosts Confidence

2026-01-30 (ET)

08:40:00

ALX Oncology Releases New Data on CD47 Inhibitor with Jazz Pharmaceuticals for Breast Cancer

News

ALXO FAQ — answered by Alphio AI

ALX Oncology Holdings Inc. is a clinical-stage biotechnology company advancing a pipeline of therapies designed to treat cancer and extend patients’ lives. The Company's lead product candidate, evorpacept, is a CD47 blocking therapeutic that combines a high-affinity CD47 binding domain with an inactivated, proprietary Fc domain. It is engaged in focusing on combining evorpacept with anti-cancer antibodies, antibody drug conjugate (ADCs), and PD-1/PD-L1 immune checkpoint inhibitors. Evorpacept is being evaluated across multiple ongoing clinical trials in a range of cancer indications. Its second product candidate is ALX2004, an epidermal growth factor receptor (EGFR)-targeted ADC. ALX2004 comprises an affinity-tuned EGFR antibody backbone engineered for optimal activity as an ADC, a proprietary topoisomerase I inhibitor payload with enhanced bystander effect, and a linker with enhanced stability. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

ALX Oncology Holdings Inc is a good buy right now due to its recent price increase of 21.24% over the last five days, indicating strong momentum. The current price of $1.37 is well below its 52-week high of $2.66, suggesting potential for growth. Additionally, the company has sufficient cash reserves of $153.4 million to fund operations through mid-2028, which provides a buffer against financial instability. However, the main risk is the negative earnings trend, with a projected EPS of -0.14 for the upcoming earnings report on November 6, 2026.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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