Acrivon Therapeutics, Inc.

Acrivon Therapeutics, Inc. (ACRV) Stock Analysis

$1.570

-0.153 (-9.77%)At close

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High
1.730
Open
1.730
VWAP
1.60
Volume
315.31K
Mkt Cap
177.85M
Low
1.510
Amount
505.55K
EV/EBITDA, TTM
0.00

Acrivon Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing precision oncology medicines. It uses its precision Generative Phosphoproteomics platform, Acrivon Predictive Precision Proteomics (AP3), to develop its pipeline of oncology drug candidates. Its lead candidate, ACR-368, is a selective small molecule inhibitor which targets CHK1 and CHK2 at sub single-digit nM and single-digit nM potency in intact cells, respectively, in a registrational Phase II trial across multiple solid tumor types. Using its AP3 platform, it has developed a predictive OncoSignature test for ACR-368, called ACR-368 OncoSignature, that can predict patient response to ACR-368 monotherapy and therefore improve the clinical overall response rate (ORR) and has the potential to enable drug development. Its preclinical program, ACR-2316, is advancing in investigational new drug-enabling studies. It is a novel, dual WEE1 and PKMYT1 inhibitor small molecule development candidate.

acrivon.com

AI analysis of Acrivon Therapeutics, Inc. (ACRV)

Hold

Acrivon Therapeutics Inc is currently not a strong buy due to its low price and negative earnings, but it shows potential for recovery. The current price is $1.61, significantly below the 52-week high of $3.56, indicating a 14.8% position within its 52-week range. However, the RSI is at 27.156, suggesting the stock is oversold, which could indicate a potential rebound. The forward P/E ratio is 0, reflecting uncertainty in future earnings, and the company has reported consistent losses, with a net income of -$19,042,000 in Q1 2026. The main risk is the ongoing negative earnings trend, as indicated by the EPS of -0.49 for Q1 2026, which may deter investors in the short term.

Valuation Metrics

The current forward P/E ratio for Acrivon Therapeutics, Inc. (ACRV) is 0.00, compared to its 5-year average forward P/E of -2.66.

Forward P/E

Overvalued
5Y Average P/E
-2.66
Current P/E
0.00
Overvalued
-0.97
Undervalued
-4.36

Forward EV/EBITDA

Strongly Undervalued
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued
0.00
Undervalued
0.00

Forward P/S

Fair
5Y Average P/S
119.40
Current P/S
0.00
Overvalued
325.94
Undervalued
-87.14

Alphio AI Price Scenarios for ACRV

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%ACRV

$1.53

Scenario price

B

Base

Base · 50%ACRV

$1.27

Scenario price

B

Bear

Bear · 25%ACRV

$1.21

Scenario price

Whales holding ACRV

R

RA Capital Management, L.P.

+ HoldingACRV

+13.94%

3M Return

Events Timeline

2026-08-12 (ET)

17:00:00

Acrivon CEO Looks Forward to Rapid Clinical Advancements in Precision Medicine in H2 2026

2026-05-13 (ET)

16:50:00

Acrivon to Advance Two Clinical Programs in 2026

2026-03-19 (ET)

07:30:00

Company Plans to Initiate Fourth Cohort of ACR-368 Study in H1 2026

07:30:00

Company Cash and Investments Reach $118.6 Million, Sufficient to Fund Until Q2 2027

07:30:00

Acrivon CEO Highlights ACR-368's Potential in Endometrial Cancer

News

ACRV FAQ — answered by Alphio AI

Acrivon Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing precision oncology medicines. It uses its precision Generative Phosphoproteomics platform, Acrivon Predictive Precision Proteomics (AP3), to develop its pipeline of oncology drug candidates. Its lead candidate, ACR-368, is a selective small molecule inhibitor which targets CHK1 and CHK2 at sub single-digit nM and single-digit nM potency in intact cells, respectively, in a registrational Phase II trial across multiple solid tumor types. Using its AP3 platform, it has developed a predictive OncoSignature test for ACR-368, called ACR-368 OncoSignature, that can predict patient response to ACR-368 monotherapy and therefore improve the clinical overall response rate (ORR) and has the potential to enable drug development. Its preclinical program, ACR-2316, is advancing in investigational new drug-enabling studies. It is a novel, dual WEE1 and PKMYT1 inhibitor small molecule development candidate. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Acrivon Therapeutics Inc is currently not a strong buy due to its low price and negative earnings, but it shows potential for recovery. The current price is $1.61, significantly below the 52-week high of $3.56, indicating a 14.8% position within its 52-week range. However, the RSI is at 27.156, suggesting the stock is oversold, which could indicate a potential rebound. The forward P/E ratio is 0, reflecting uncertainty in future earnings, and the company has reported consistent losses, with a net income of -$19,042,000 in Q1 2026. The main risk is the ongoing negative earnings trend, as indicated by the EPS of -0.49 for Q1 2026, which may deter investors in the short term.

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