$25.030
-0.701 (-2.80%)At close
ZYME News
ZYME Events
Major Averages Decline as Oil Prices Come into Focus
The major averages had a down day to start the week, with oil prices in focus after President Donald Trump rejected conditions for a ceasefire presented by Iran. Meanwhile, Treasury yields continued to climb to multi-year highs amid expectations that higher energy prices could put further pressure on inflation and increase the likelihood of additional rate hikes.Get caught up quickly on the top news and calls moving stocks with these five Top Five lists.1. STOCK NEWS:Nvidiahas launched an agent safety platform following recent security incidents and authorized an additional $150B under its existing share repurchase programMongoDBCEO Chirantan Desai has left the company to take on the role as Meta'sEnterprise Platform OfficerBoeinghas discovered a glitch to the 737 MAX software that could cause its automated navigation feature to fail, WSJ reportsBrixmorand Everview Partners agreed to acquire Slate Grocery REITfor $2.34BJana Partners is pushing Fiservto more than double planned cost reductions, Reuters reports2. WALL STREET CALLS:Royal Caribbeanupgraded to Buy at both Deutsche Bank and BofARobloxdowngraded to Underperform at JefferiesPark Hotelsupgraded to Strong Buy from Market Perform at Raymond JamesPepsiCodowngraded to Hold from Buy at Deutsche BankSweetgreenupgraded to Overweight at Wells Fargo3. AROUND THE WEB:The White House is weighing broader use of tax-exempt red-dyed diesel as an alternative to restricting exports, Reuters reportsTrump is expected to announce a $15B Mesabi Metallics steel factory in Iowa, Bloomberg saysAirbusand Leonardoare investigating a coatings defect affecting about 500 A321neo jets, Reuters reportsFugazi Research said in a new research report that the firm considers Greenland Energy'sstock "uninvestable" at "any price above zero"A EUR 10.3B bid by BASFfor Evonikhas been rejected as too low to warrant negotiations, setting up a potential takeover battle as Evonik pursues restructuring and divestitures amid broader consolidation in Europe's challenged chemicals industry, FT reports4. MOVERS:Kodiak Sciencessurged after announcing its Phase 3 DAYBREAK study met its primary endpointsBurford Capitalincreased after issuing comments related to the patent matter between Apple and TactionGE Aerospaceslipped after Bloomberg reported the FAA intends to delay certification of Boeing's 737 Max 10 aircraft as it reviews a potential issue with software developed by GE AerospaceGold Fieldsfell in New York after announcing its offer was rejected by Northern Star Resources boardNubankwas lower in New York after Bloomberg reported the company is in talks to acquire Monzo Bank for GBP8B-GBP10B5. EARNINGS/GUIDANCE:Zymeworksprovided guidance for FY26NetSol Technologiesreported Q4 results, with EPS and revenue higher year-over-yearGray Mediaannounced its outlook for Q3Kandi Technologiesreported results for H1, with EPS and revenue higher year-over-yearVestisreaffirmed its guidance for FY26INDEXES:The Dow fell 347.11, or 0.67%, to 51,481.51, the Nasdaq lost 248.34, or 0.92%, to 26,820.38, and the S&P 500 declined 59.72, or 0.77%, to 7,683.69.
Zymeworks Completes Acquisition of Theravance Biopharma
LifeSci Capital notes Zymeworks (ZYME) announced the completion of the Theravance Biopharma (TBPH) acquisition. Yupelri is expected to be immediately accretive to revenue and cash flow, with a mid-teens IRR as the base case. Zymeworks emphasized commercial expansion opportunities in both community and hospital settings, noting that Yupelri remains under-penetrated, with a "single-digit" penetration rate in a large COPD market of 15M-16M patients, of whom about 2M are "well-suited" for a nebulized product, the firm notes. The company will retain Theravance's "small, high-performing" commercial team, although details on the sales force were not provided. Management intentionally remained conservative on providing detailed financial guidance, while underscoring that the company remains focused on cost discipline with respect to operating expenses. LifeSci has an Outperform rating on Zymeworks with a price target of $34.
Major Averages Broadly Lower as Oil Prices Surge Over 3%
The major averages were broadly lower to start the week, with oil prices surging over 3% after President Donald Trump rejected conditions for a ceasefire presented by Iran. Treasury yields are also rising while several AI stocks, including AMD and Micron, were slipping.Get caught up quickly on the top news and calls moving stocks with these five Top Five lists.1. STOCK NEWS:Nvidiahas launched an agent safety platform following recent security incidents and authorized an additional $150B under its existing share repurchase programMongoDBCEO Chirantan Desai has left the company to take on the role as Meta'sEnterprise Platform OfficerBoeinghas discovered a glitch to the 737 MAX software that could cause its automated navigation feature to fail, WSJ reportsBrixmorand Everview Partners agreed to acquire Slate Grocery REITfor $2.34BJana Partners is pushing Fiservto more than double planned cost reductions, Reuters reports2. WALL STREET CALLS:Royal Caribbeanupgraded to Buy at both Deutsche Bank and BofARobloxdowngraded to Underperform at JefferiesPark Hotelsupgraded to Strong Buy from Market Perform at Raymond JamesPepsiCodowngraded to Hold from Buy at Deutsche BankSweetgreenupgraded to Overweight at Wells Fargo3. AROUND THE WEB:Airbusand Leonardoare investigating a coatings defect affecting about 500 A321neo jets, Reuters reportsUber'sKenyan safari business is facing resistance from local guides, WSJ saysFugazi Research said in a new research report that the firm considers Greenland Energy'sstock "uninvestable" at "any price above zero"A EUR 10.3B bid by BASFfor Evonikhas been rejected as too low towarrant negotiations, setting up a potential takeover battle as Evonik pursues restructuring and divestitures amid broader consolidation in Europe's challenged chemicals industry, FT reportsMetaVR Glasses is the product Apple'sVision Pro should have been, Bloomberg says4. MOVERS:Kodiak Sciencesgains after announcing its Phase 3 DAYBREAK study met its primary endpointsBurford Capitalincreases after issuing comments related to the patent matter between Apple and TactionLexiconhigher after Cantor Fitzgerald initiated coverage of the stock with an Overweight ratingGold Fieldsfalls in New York after announcing its offer was rejected by Northern Star Resources boardNubanklower in New York after Bloomberg reported the company is in talks to acquire Monzo Bank for GBP 8B - GBP 10B5. EARNINGS/GUIDANCE:Zymeworksprovided guidance for FY26NetSol Technologiesreported Q4 results, with EPS and revenue higher year-over-yearGray Mediaannounced its outlook for Q3Kandi Technologiesreported results for H1, with EPS and revenue higher year-over-yearVestisreaffirmed its guidance for FY26INDEXES:Near midday, the Dow was down 372.37, or 0.72%, to 51,456.25, the Nasdaq was down 251.04, or 0.93%, to 26,817.68, and the S&P 500 was down 61.51, or 0.79%, to 7,681.90.
Zymeworks Acquisition Expected to Generate $25-30 Million Incremental Revenue
The acquisition is expected to provide Zymeworks with meaningful and immediate incremental revenue and operating cash flow following closing, including: Mid-teens base-case IRR, supported primarily by growth in YUPELRI revenues and a smaller contribution from VIBATIV. This base case does not include potential upside contributions from utilization of tax attributes or future R&D or business development opportunities. 25% growth in YUPELRI hospital sales in the second quarter of 2026, supporting continued margin expansion and increasing operating leverage as net sales continue to scale. Hospital channel growth remains a key driver of the product's continued expansion in the community setting. Acquisition and restructuring-related costs, excluding capitalized costs attributed to the OMERS Life Sciences non-recourse financing, of approximately $25-30 million. $2.5 billion of Irish tax attributes, which may provide additional flexibility to generate value from future Irish revenues, IP structuring and potential acquisitions or investments through the company's existing Irish R&D operations. No value has been assigned to the utilization of these tax attributes in the transaction valuation or base case IRR, and any future utilization would therefore represent additional upside. Potential $100 million TRELEGY ELLIPTA milestone payment expected in the first quarter of 2027, assuming milestone conditions met, offsetting cash outlay for the purchase price.
Zymeworks Updates Financial Guidance for 2026
With the completion of the Theravance Biopharma acquisition and the receipt of the U.S. FDA approval of Ziihera for first-line HER2-positive advanced gastroesophageal adenocarcinoma on August 25, 2026, the company has provided updated financial guidance utilizing relevant financial metrics that it believes provide a more suitable framework for evaluating operating performance of the business. "The company expects total revenue for 2026 to be between $278 million and $292 million and 2026 Adjusted EBITDA to be between $114 million and $128 million, excluding the impact of any future transactions," stated Kristin Stafford, CFO of Zymeworks. "During 2026, we have been able to access a total of $600 million in non-dilutive financing in the form of non-recourse notes at an attractive cost of capital, with proceeds being utilized to fund both the Theravance Biopharma acquisition and continued share repurchases. Our financing strategy and the share repurchase program have focused on minimizing equity dilution to our shareholders. We completed our last public equity offering in January 2022 and have no current plans for additional equity issuances."
This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.







