Sarepta Therapeutics Inc

Sarepta Therapeutics Inc (SRPT) Stock Analysis

$17.730

+0.652 (+3.68%)At close

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High
17.830
Open
17.250
VWAP
17.56
Volume
2.33M
Mkt Cap
—
Low
17.120
Amount
40.90M
EV/EBITDA, TTM
10.48

Sarepta Therapeutics, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on helping patients through the discovery and development of ribonucleic acid (RNA)-targeted therapeutics, siRNA knockdown therapies, gene therapy and other genetic therapeutic modalities for the treatment of rare diseases. It has developed multiple approved products for the treatment of Duchenne muscular dystrophy (Duchenne) and is developing potential therapeutic candidates for a range of diseases and disorders, including Duchenne, Limb-girdle muscular dystrophies (LGMDs) and other neuromuscular and central nervous system (CNS) related disorders. The Company has developed and commercialized four approved products for the treatment of Duchenne: EXONDYS 51 (eteplirsen), Injection (EXONDYS 51), VYONDYS 53 (golodirsen) Injection (VYONDYS 53), AMONDYS 45 (casimersen) Injection (AMONDYS 45), and ELEVIDYS.

AI analysis of Sarepta Therapeutics Inc (SRPT)

Hold

Sarepta Therapeutics Inc is currently trading at $17.10, which is below the average analyst price target of $20, indicating potential upside. However, the RSI is at 42.01, suggesting the stock is nearing oversold conditions but not yet in a strong buy zone. The company has shown a gross margin of 85.02% in Q1 2026, indicating strong profitability, but it has faced significant revenue declines, with a 25.81% drop in the past year. The main risk is the hedge fund selling activity, which has increased by 12693.27% over the last quarter, indicating a lack of confidence from institutional investors. Therefore, while there are some positive indicators, the overall sentiment and selling pressure suggest holding off on buying for now.

Analyst Ratings (18)

+17.32% upside
Buy
17 Buy
1 Hold
0 Sell
Current: 17.73
Low
5.00
Average
20.80
High
45.00

RBC Capital

2026-10-08

Price Target

$17

Sector Perform

JPMorgan

2026-09-30

Price Target

$20

Neutral

Mizuho

2026-09-08

Price Target

$31

Outperform

Jefferies

2026-09-08

Price Target

$30

Buy

H.C. Wainwright

2026-09-08

Price Target

$5

Sell

Valuation Metrics

The current forward P/E ratio for Sarepta Therapeutics Inc (SRPT) is 19.16, compared to its 5-year average forward P/E of 9.09.

Forward P/E

Fair
5Y Average P/E
9.09
Current P/E
19.16
Overvalued
45.45
Undervalued
-27.26

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
5.72
Current EV/EBITDA
10.48
Overvalued
90.72
Undervalued
-79.29

Forward P/S

Undervalued
5Y Average P/S
5.26
Current P/S
1.36
Overvalued
8.38
Undervalued
2.14

Alphio AI Price Scenarios for SRPT

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%SRPT

$69.79

Scenario price

B

Base

Base · 50%SRPT

$58.09

Scenario price

B

Bear

Bear · 25%SRPT

$50.13

Scenario price

Whales holding SRPT

C

Casdin Capital, LLC

+ HoldingSRPT

-4.73%

3M Return

A

ADAR1 Capital Management, LLC

+ HoldingSRPT

-14.67%

3M Return

Events Timeline

2026-10-14 (ET)

09:00:00

Sarepta Therapeutics Presents Preclinical Data on SRP-1003

2026-09-30 (ET)

09:00:00

Sarepta Presents ELEVIDYS Efficacy Data in Duchenne Muscular Dystrophy Patients

2026-08-05 (ET)

17:00:00

Sarepta Reports Q2 Revenue of $401.3M

2026-07-27 (ET)

11:00:00

Morgan Stanley Notes Sarepta's New CEO Appointment

09:00:00

Sarepta Therapeutics Appoints Michael Severino as CEO

News

SRPT FAQ — answered by Alphio AI

Sarepta Therapeutics, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on helping patients through the discovery and development of ribonucleic acid (RNA)-targeted therapeutics, siRNA knockdown therapies, gene therapy and other genetic therapeutic modalities for the treatment of rare diseases. It has developed multiple approved products for the treatment of Duchenne muscular dystrophy (Duchenne) and is developing potential therapeutic candidates for a range of diseases and disorders, including Duchenne, Limb-girdle muscular dystrophies (LGMDs) and other neuromuscular and central nervous system (CNS) related disorders. The Company has developed and commercialized four approved products for the treatment of Duchenne: EXONDYS 51 (eteplirsen), Injection (EXONDYS 51), VYONDYS 53 (golodirsen) Injection (VYONDYS 53), AMONDYS 45 (casimersen) Injection (AMONDYS 45), and ELEVIDYS. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Sarepta Therapeutics Inc is currently trading at $17.10, which is below the average analyst price target of $20, indicating potential upside. However, the RSI is at 42.01, suggesting the stock is nearing oversold conditions but not yet in a strong buy zone. The company has shown a gross margin of 85.02% in Q1 2026, indicating strong profitability, but it has faced significant revenue declines, with a 25.81% drop in the past year. The main risk is the hedge fund selling activity, which has increased by 12693.27% over the last quarter, indicating a lack of confidence from institutional investors. Therefore, while there are some positive indicators, the overall sentiment and selling pressure suggest holding off on buying for now.

18 analysts cover SRPT: 17 rate it Buy, 1 Hold and 0 Sell. The average price target is 20.80.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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