Septerna Inc (SEPN) FinancialsSEPNSepterna Inc

Evaluating the bottom line, Septerna, Inc. maintains a gross margin of 100.00%. This metric reflects the company's pricing power and manufacturing efficiency. Further down the income statement, the operating margin stands at -62.95%, while the net margin is -48.73%. These profitability ratios, combined with a Return on Equity (ROE) of -6.34%, provide a clear picture of how effectively SEPN converts its operational activities into shareholder value.

In the context of the broader market, SEPN competes directly with industry leaders such as XNCR and TRVI. With a market capitalization of $1.79B, it holds a significant position in the sector. When comparing efficiency, SEPN's gross margin of 100.00% stands against XNCR's 100.00% and TRVI's N/A. Such benchmarking helps identify whether Septerna, Inc. is trading at a premium or discount relative to its financial performance.

The company has shown significant revenue growth, with Q2 2026 revenue at $26,746,000, but it continues to report net losses, with a net income of -$13,034,000 in Q2 2026. The gross margin remains strong at 100%, but the net margin is negative, indicating ongoing challenges in profitability.