Cyclerion Therapeutics Inc

Cyclerion Therapeutics Inc (CYCN) Stock Analysis

$23.520

-4.925 (-20.94%)At close

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High
26.880
Open
26.040
VWAP
23.38
Volume
62.49K
Mkt Cap
5.37M
Low
19.740
Amount
1.46M
EV/EBITDA, TTM
0.00

Korsana Biosciences, Inc., formerly Cyclerion Therapeutics, Inc., is a biotechnology company discovering and developing novel therapies to reduce the burden of neurodegenerative diseases. The Company's lead program, KRSA-028, is a next-generation shuttle antibody targeting amyloid beta for the treatment of Alzheimer’s disease. KRSA-028 leverages Therapeutic Targeting (THETA), a novel CNS shuttle technology developed in partnership with Paragon Therapeutics and designed to enable dramatically higher drug concentrations in the brain and overcome the limitations of earlier shuttle technologies. In addition, it is advancing a pipeline of innovative therapies for neurodegenerative diseases.

AI analysis of Cyclerion Therapeutics Inc (CYCN)

Buy

Cyclerion Therapeutics Inc (CYCN) is currently a good buy due to its recent merger announcement with Korsana Biosciences, which has significantly boosted investor sentiment and resulted in a stock price increase of over 150%. The stock has shown a year-to-date change of +217.16%, indicating strong momentum. However, the main risk is its negative earnings, with a recent EPS of -0.41 and a forward P/E ratio of 0, suggesting uncertainty in profitability moving forward.

Valuation Metrics

The current forward P/E ratio for Cyclerion Therapeutics Inc (CYCN) is 0.00, compared to its 5-year average forward P/E of -0.34.

Forward P/E

Fair
5Y Average P/E
-0.34
Current P/E
0.00
Overvalued
0.06
Undervalued
-0.74

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-0.03
Current EV/EBITDA
0.00
Overvalued
0.13
Undervalued
-0.18

Forward P/S

Fair
5Y Average P/S
5.41
Current P/S
0.00
Overvalued
17.00
Undervalued
-6.18

Alphio AI Price Scenarios for CYCN

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%CYCN

$4.06

Scenario price

B

Base

Base · 50%CYCN

$3.48

Scenario price

B

Bear

Bear · 25%CYCN

$2.82

Scenario price

Events Timeline

2026-09-08 (ET)

20:00:00

Cyclerion Therapeutics Trading Halted, News Pending

2026-04-01 (ET)

07:10:00

Cyclerion and Korsana Enter Merger Agreement

2026-02-17 (ET)

07:20:00

Cyclerion Receives Positive FDA Feedback on CYC-126

2026-01-05 (ET)

16:10:00

Cyclerion Announces Exclusive Collaboration with Medsteer

2025-12-22 (ET)

16:50:00

Cycurion Files to Sell 4.97M Shares of Common Stock for Holders

News

CYCN FAQ — answered by Alphio AI

Korsana Biosciences, Inc., formerly Cyclerion Therapeutics, Inc., is a biotechnology company discovering and developing novel therapies to reduce the burden of neurodegenerative diseases. The Company's lead program, KRSA-028, is a next-generation shuttle antibody targeting amyloid beta for the treatment of Alzheimer’s disease. KRSA-028 leverages Therapeutic Targeting (THETA), a novel CNS shuttle technology developed in partnership with Paragon Therapeutics and designed to enable dramatically higher drug concentrations in the brain and overcome the limitations of earlier shuttle technologies. In addition, it is advancing a pipeline of innovative therapies for neurodegenerative diseases. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Cyclerion Therapeutics Inc (CYCN) is currently a good buy due to its recent merger announcement with Korsana Biosciences, which has significantly boosted investor sentiment and resulted in a stock price increase of over 150%. The stock has shown a year-to-date change of +217.16%, indicating strong momentum. However, the main risk is its negative earnings, with a recent EPS of -0.41 and a forward P/E ratio of 0, suggesting uncertainty in profitability moving forward.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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