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Pathos AI Announces Strategic Collaboration with Bristol Myers Squibb
Pathos AI announced multi-year strategic collaborations with Bristol Myers Squibb (BMY) and Tempus AI (TEM) to build a specialized, curated dataset and agentic AI capabilities for Alzheimer's disease and other neurological conditions. BMS also leads Pathos's Series E financing and gains access to Pathos Foundry across its broader R&D portfolio. Tempus will apply the infrastructure and expertise it has built in oncology to create a comprehensive, de-identified, longitudinal dataset from hundreds of thousands of patients with neurological conditions, designed to track outcomes over time and accelerate biological insight. Pathos will license the data from Tempus under a five-year, $55M agreement. Pathos will apply its AI platform, Pathos Foundry, to interrogate the dataset at scale, generate and test hypotheses on disease biology, and inform the design of more targeted, adaptive clinical trials. Pathos built and validated this approach in oncology, where it guides decisions across the company's clinical-stage pipeline, including adapting trial design in real time to improve its projected probability of success. The collaboration builds on BMS's broader strategy to combine advanced AI with deep scientific and disease-area expertise to make faster, higher-confidence decisions that drive innovation for patients. BMS is helping expand the application of Pathos Foundry into neuroscience, securing three-year exclusive rights in an area where the company brings deep research, clinical-development expertise and a growing portfolio of programs in Alzheimer's disease and other neurological conditions. Through multi-year access to the platform across its broader portfolio and the specialized dataset developed through the definitive agreements, BMS aims to generate deeper insights into disease progression, identify patients most likely to benefit from potential therapies and design more precise clinical trials.
Tempus AI Signs Multi-Year Agreement with Bristol Myers Squibb
Tempus AI (TEM) announced a multi-year agreement with Bristol Myers Squibb (BMY), under which BMS will license multimodal oncology data from Tempus through 2031 to support biological and clinical insight identification, novel drug target discovery and therapeutic development across its oncology portfolio. With this agreement, BMS significantly expands its strategic relationship with Tempus and becomes one of Tempus's largest licensors of de-identified oncology data. Additionally, BMS will gain access to Tempus' Lens Platform, an AI-first, agentic platform for oncology drug development built on one of the world's largest, real-world multimodal datasets. Connected to GPU infrastructure, this dedicated environment will allow BMS researchers to train and execute advanced AI models using de-identified data to surface breakthroughs faster and increase the probability of technical success when developing candidate therapies at scale.
Tempus AI Announces Results of NSCLC Study
Tempus AI announced results from a study evaluating an AI-enabled pre-screening panel for patients with advanced non-small cell lung cancer, NSCLC. The panel achieved greater than 80% sensitivity across all 12 biomarkers assessed, with sensitivity exceeding 90% for several biomarkers, supporting its potential to identify patients who may need confirmatory biomarker testing. Results from the study were presented at the European Society for Medical Oncology, ESMO, Congress 2026 in Madrid. "Precision medicine only works when clinicians have the right information at the right time," said Ezra Cohen, MD, Chief Medical Officer of Oncology at Tempus. "These findings demonstrate the potential for AI to extract meaningful information from a pathology image that is already part of routine care and help clinicians determine what testing may be most important next. This builds on our efforts to apply AI to routine diagnostic data to help more patients benefit from precision medicine."
Major Averages Decline After Fed Meeting Minutes Release
The major averages closed lower after the release of the Federal Reserve's September meeting minutes. According to minutes from the latest FOMC meeting, most Fed members are seeing increased economic momentum and expect another rate hike by year-end. Many members see higher rates on risk-management grounds, the minutes showed. Of note, the benchmark 10-year Treasury yield rose more than eight basis points to trade as high as 5.356%, reaching its highest level since April 2002.Get caught up quickly on the top news and calls moving stocks with these five Top Five lists.1. STOCK NEWS:Chevronwill divest ownership interests in Hess Midstreamand DJ Basin crude assetsConstellation Brandsreported upbeat Q2 results and provided FY27 guidanceSpaceXis seeking to raise $40B to purchase Nvidiachips, FT reportsMicrosoftintends to unveil a new laptop that utilizes Nvidiachips, Reuters reportsAccording to minutes from the last Federal Reserve meeting, most Fed members expect another rate hike by year-end2. WALL STREET CALLS:Marvellupgraded to Buy at TD CowenAppFoliodowngraded to Neutral at UBSFlutter Entertainmentupgraded to Buy at CitiMohawk Industriesdowngraded to Underperform at RBC CapitalCantor upgraded Humanainto this week's Stars announcement by CMS3. AROUND THE WEB:Disney+will stream Super Bowl LXI in 2027, Variety reportsThe Trump administration's HUD is investigating Wells Fargoover nearly a decade of programs aimed at increasing Black homeownership, examining whether the bank's commitments and practices violated fair-lending laws by favoring Black or other minority borrowers, WSJ reportsThe U.S. government, Meta, Google DeepMind, and Isomorphic Labs are committing $1.8B to Biohub's effort to build standardized open biological datasets for AI training, Reuters saysThe FBI removed an Accenturecontractor due to their role in a data breach that exposed the personal details of thousands of FBI employees, Reuters saysA workers' union at Micron'sTaiwan facility has received an authorization from its members to strike over the dispute regarding the company's bonus scheme, Reuters reports4. MOVERS:HPEgained after announcing the first four of its HPE ProLiant Gen13 Servers powered by 6th Generation AMDEPYC Server processorsModernaincreased after entering a multi-year collaboration with Tempus AIand MerckSkyworkswas higher after BofA raised its price target on the stockFarm equipment makers Deere, Caterpillar, CNH Industrial, and Agcofell after the FTC launched a probe into the sector over possible anticompetitive conductFortuna Miningwas lower in New York after reporting production results for Q35. EARNINGS/GUIDANCE:Safe Proreported preliminary Q3 resultsPenguin Solutionsreported Q4 results and provided guidance for FY27Neogenreported Q1 results and raised its outlook for FY27PepsiCoto report Q3 results on October 8Delta Air Linesto report Q3 results on October 9INDEXES:The Dow fell 341.41, or 0.66%, to 51,179.87, the Nasdaq lost 61.20, or 0.22%, to 27,538.69, and the S&P 500 declined 17.16, or 0.22%, to 7,801.77.
Major Averages Broadly Lower as 10-Year Treasury Yield Rises to 5.356%
The major averages were broadly lower near noon amid an increase in bond yields and oil prices and ahead of the release of the Federal Reserve's September meeting minutes. The benchmark 10-year Treasury note yield rose more than eight basis points to trade as high as 5.356%, reaching its highest level since April 2002.The Fed's September meeting minutes could provide a clearer picture of the debate behind the central bank's 25-basis-point rate hike. Markets broadly expect the Fed to hold rates at its Oct. 27-28 meeting following last week's weaker jobs report, but expectations for another hike later in the year remain.Get caught up quickly on the top news and calls moving stocks with these five Top Five lists.1. STOCK NEWS:Chevronwill divest ownership interests in Hess Midstreamand DJ Basin crude assetsConstellation Brandsreported upbeat Q2 results and provided FY27 guidanceSpaceXis seeking to raise $40B to purchase Nvidiachips, FT reportsMicrosoftintends to unveil a new laptop that utilizes Nvidiachips, Reuters reportsDisney+will stream Super Bowl LXI in 2027, Variety reports2. WALL STREET CALLS:Marvellupgraded to Buy at TD CowenAppFoliodowngraded to Neutral at UBSFlutter Entertainmentupgraded to Buy at CitiMohawk Industriesdowngraded to Underperform at RBC CapitalCantor upgraded Humanainto this week's Stars announcement by CMS3. AROUND THE WEB:The U.S. government, Meta, Google DeepMind, and Isomorphic Labs are committing $1.8B to Biohub's effort to build standardized open biological datasets for AI training, Reuters saysMicrosoft'sXbox has secured game streaming rights for Grand Theft Auto VI, The Verge reportsThe FBI removed an Accenturecontractor due to their role in a data breach that exposed the personal details of thousands of FBI employees, Reuters saysA workers' union at Micron'sTaiwan facility has received an authorization from its members to strike over the dispute regarding the company's bonus scheme, Reuters reportsThe bipartisan House Select Committee on China in a report to be released today found "a profound gap" between Webull'spublic marketing as "an American company" and actual control of the St. Petersburg, Florida-based firm, CNBC says4. MOVERS:HPEgains after announcing the first four of its HPE ProLiant Gen13 Servers powered by 6th Generation AMDEPYC Server processorsModernaincreases after entering a multi-year collaboration with Tempus AIand MerckSkyworkshigher after BofA raised its price target on the stockFuelCellfalls after announcing CFO Michael Bishop will transition out of the roleFortuna Mininglower in New York after reporting production results for Q35. EARNINGS/GUIDANCE:Safe Proreported preliminary Q3 resultsPenguin Solutionsreported Q4 results and provided guidance for FY27Neogenreported Q1 results and raised its outlook for FY27PepsiCoto report Q3 results on October 8Delta Air Linesto report Q3 results on October 9INDEXES:Near midday, the Dow was down 402.95, or 0.78%, to 51,118.33, the Nasdaq was down 137.31, or 0.50%, to 27,462.58, and the S&P 500 was down 28.79, or 0.37%, to 7,790.14.
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