Summit Therapeutics Inc

Summit Therapeutics Inc (SMMT) Stock Analysis

$13.730

-0.575 (-4.19%)At close

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High
14.240
Open
14.110
VWAP
13.80
Vol
3.91M
Mkt Cap
5.52B
Low
13.430
Amount
53.91M
EV/EBITDA, TTM
0.00

Summit Therapeutics Inc. is a biopharmaceutical company focused on the discovery, development, and commercialization of patient, physician, caregiver and societal-friendly medicinal therapies intended to improve quality of life, increase potential duration of life, and resolve serious unmet medical needs. Its lead development candidate is ivonescimab, a novel, potential first-in-class bispecific antibody intending to combine the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects of an anti-VEGF compound into a single molecule. Ivonescimab is being developed by both Akeso and the Company in multiple Phase III clinical trials. It is also developing ivonescimab in non-small cell lung cancer and other solid tumor settings. Ivonescimab is approved in China in combination with chemotherapy for patients with EGFR-mutated non-small cell lung cancer whose tumors have progressed following an EGFR-TKI based on the results of the HARMONi-A clinical trial.

AI analysis of Summit Therapeutics Inc (SMMT)

buy

Summit Therapeutics Inc (SMMT) is a strong buy right now due to its recent positive trial results, which led to a 7% increase in share price, and a favorable analyst price target of $38, suggesting significant upside potential. Additionally, the stock is currently trading at $13.73, which is well below the target price, making it an attractive entry point. However, investors should be cautious of the company's ongoing net losses, with a recent quarterly net income of -215.7 million USD, which poses a risk to long-term profitability.

Analyst Ratings (6)

+209.47% upside
Buy
6 Buy
0 Hold
0 Sell
Current: 13.73
Low
18.00
Average
42.49
High
131.90

Bernstein

2026-08-25

Price Target

Market Perform

Leerink

2026-08-12

Price Target

$13

Market Perform

Jefferies

2026-07-24

Price Target

$15

Hold

H.C. Wainwright

2026-07-24

Price Target

Neutral

Stifel

2026-07-24

Price Target

$38

Buy

Valuation Metrics

The current forward P/E ratio for Summit Therapeutics Inc (SMMT) is 3.72, compared to its 5-year average forward P/E of -20.62.

Forward P/E

Fair
5Y Average P/E
-20.62
Current P/E
3.72
Overvalued
6.94
Undervalued
-48.19

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-16.82
Current EV/EBITDA
0.00
Overvalued
5.01
Undervalued
-38.65

Forward P/S

Fair
5Y Average P/S
373.64
Current P/S
273.69
Overvalued
948.81
Undervalued
-201.52

Alphio AI Price Scenarios for SMMT

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%SMMT

$32.18

Scenario price

B

Base

Base · 50%SMMT

$28.61

Scenario price

B

Bear

Bear · 25%SMMT

$23.40

Scenario price

Whales holding SMMT

B

Baker Bros. Advisors LP

+ HoldingSMMT

+18.95%

3M Return

Events Timeline

2026-08-25 (ET)

18:30:00

Summit Therapeutics Partner Akeso Reports Positive Results from HARMONi-GI1 Study

07:30:00

Summit Therapeutics Publishes HARMONi Trial Results

2026-08-12 (ET)

10:00:00

Summit Therapeutics Receives China Marketing Authorization for Ivonescimab in Lung Cancer

09:30:00

Summit Therapeutics Partner Akeso Receives Marketing Authorization in China

2026-08-05 (ET)

08:00:00

Summit Therapeutics Expands Ivonescimab Clinical Development to Bladder Cancer

News

SMMT FAQ — answered by Alphio AI

Summit Therapeutics Inc. is a biopharmaceutical company focused on the discovery, development, and commercialization of patient, physician, caregiver and societal-friendly medicinal therapies intended to improve quality of life, increase potential duration of life, and resolve serious unmet medical needs. Its lead development candidate is ivonescimab, a novel, potential first-in-class bispecific antibody intending to combine the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects of an anti-VEGF compound into a single molecule. Ivonescimab is being developed by both Akeso and the Company in multiple Phase III clinical trials. It is also developing ivonescimab in non-small cell lung cancer and other solid tumor settings. Ivonescimab is approved in China in combination with chemotherapy for patients with EGFR-mutated non-small cell lung cancer whose tumors have progressed following an EGFR-TKI based on the results of the HARMONi-A clinical trial. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Summit Therapeutics Inc (SMMT) is a strong buy right now due to its recent positive trial results, which led to a 7% increase in share price, and a favorable analyst price target of $38, suggesting significant upside potential. Additionally, the stock is currently trading at $13.73, which is well below the target price, making it an attractive entry point. However, investors should be cautious of the company's ongoing net losses, with a recent quarterly net income of -215.7 million USD, which poses a risk to long-term profitability.

6 analysts cover SMMT: 6 rate it Buy, 0 Hold and 0 Sell. The average price target is 42.49.

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