Silence Therapeutics PLC

Análisis de la acción Silence Therapeutics PLC (SLN)

$13.420

-0.030 (-0.22%)Al cierre

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High
13.685
Open
13.460
VWAP
13.43
Vol
539.70K
Mkt Cap
886.54M
Low
13.180
Amount
7.25M
EV/EBITDA, TTM
-9.82

Silence Therapeutics plc is a global clinical-stage biotechnology company engaged in transforming people’s lives by silencing diseases through precision-engineered medicines created with proprietary siRNA (short interfering RNA) technology. The Company leverages its mRNAi GOLD platform to create siRNAs designed to precisely target and silence disease-associated genes in the liver. The Company focuses on areas of high unmet medical need with programs advancing cardiovascular disease, hematology and rare diseases. Divesiran (SLN124) is its wholly owned siRNA product candidate designed to inhibit TMPRSS6 expression in the liver. Zerlasiran is a siRNA molecule designed for the treatment of cardiovascular disease associated with elevated Lp(a), a lipoprotein in the blood. In addition to its wholly owned clinical pipeline, it has a third siRNA product candidate from its mRNAi GOLD platform in Phase I development in an undisclosed indication through its collaboration with AstraZeneca.

AI analysis of Silence Therapeutics PLC (SLN)

buy

Silence Therapeutics PLC is a good buy right now due to its recent positive catalysts, including a successful Phase 2 trial for Divesiran, which showed an 88% response rate in treated patients. The current price of $13.42 is significantly lower than the analyst price target of $32 from Morgan Stanley, indicating a potential upside of 138%. Additionally, the stock has experienced a year-to-date change of +118.21%, reflecting strong momentum. However, investors should be cautious of the company's high net losses, which reached -$12.68 million in Q2 2026, posing a risk to financial stability.

Métricas de valoración

The current forward P/E ratio for Silence Therapeutics PLC (SLN) is 0.00, compared to its 5-year average forward P/E of -14.55.

Forward P/E

Overvalued
5Y Average P/E
-14.55
Current P/E
0.00
Sobrevalorada
-0.38
Infravalorada
-28.73

Forward EV/EBITDA

Undervalued
5Y Average EV/EBITDA
-4.90
Current EV/EBITDA
-9.82
Sobrevalorada
-0.06
Infravalorada
-9.75

Forward P/S

Strongly Overvalued
5Y Average P/S
43.36
Current P/S
1113.84
Sobrevalorada
145.55
Infravalorada
-58.84

Alphio AI Price Scenarios for SLN

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%SLN

$2.94

Precio del escenario

B

Base

Base · 50%SLN

$2.39

Precio del escenario

B

Bear

Bear · 25%SLN

$1.80

Precio del escenario

Whales holding SLN

A

Artal Group S.A.

+ HoldingSLN

-0.61%

3M Return

T

TCG Crossover Management, LLC

+ HoldingSLN

-4.24%

3M Return

Cronología de eventos

2026-08-12 (ET)

09:00:00

Significant Increases in Borrow Rates for Liquid Options

2026-08-10 (ET)

17:00:00

Jefferies, Morgan Stanley, and Others Jointly Manage Proposed Offering

08:00:00

Silence Therapeutics Reports Positive Phase 2 Results for Divesiran

07:30:00

SLN365 and SLN098 Preclinical Data Updates

2026-05-18 (ET)

16:20:00

Silence Therapeutics Files $300M Ordinary Shares Offering

Noticias

SLN FAQ — answered by Alphio AI

Silence Therapeutics plc is a global clinical-stage biotechnology company engaged in transforming people’s lives by silencing diseases through precision-engineered medicines created with proprietary siRNA (short interfering RNA) technology. The Company leverages its mRNAi GOLD platform to create siRNAs designed to precisely target and silence disease-associated genes in the liver. The Company focuses on areas of high unmet medical need with programs advancing cardiovascular disease, hematology and rare diseases. Divesiran (SLN124) is its wholly owned siRNA product candidate designed to inhibit TMPRSS6 expression in the liver. Zerlasiran is a siRNA molecule designed for the treatment of cardiovascular disease associated with elevated Lp(a), a lipoprotein in the blood. In addition to its wholly owned clinical pipeline, it has a third siRNA product candidate from its mRNAi GOLD platform in Phase I development in an undisclosed indication through its collaboration with AstraZeneca. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Silence Therapeutics PLC is a good buy right now due to its recent positive catalysts, including a successful Phase 2 trial for Divesiran, which showed an 88% response rate in treated patients. The current price of $13.42 is significantly lower than the analyst price target of $32 from Morgan Stanley, indicating a potential upside of 138%. Additionally, the stock has experienced a year-to-date change of +118.21%, reflecting strong momentum. However, investors should be cautious of the company's high net losses, which reached -$12.68 million in Q2 2026, posing a risk to financial stability.

Esta página es solo para investigación y no constituye asesoramiento de inversión. Los modelos pueden equivocarse. El rendimiento pasado no garantiza resultados futuros.

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