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Noticias de NBIX
Eventos de NBIX
Major Indices Decline as Oil Prices Surge
Major indices started the week on a downswing as oil prices sprang higher after President Donald Trump rejected conditions for a ceasefire presented by Iran and Treasury yields extended their upward jolt for the 5th consecutive session. Defensively oriented Healthcare and Consumer Staples were the best-performing sectors on the benchmark, while Basic Materials was the worst area of the market, though Communication Services was not far behind as traders booked profits from the recent surge in shares of Meta Platformsfor the second consecutive day. Precious metals stocks tracked the prices of Gold and Silver - both of which slipped to multi-week lows - to the downside.In the opening hour of the evening session, index futures are marginally higher, with S&P e-minis and Nasdaq 100 contracts up 0.1%. KarMaxand Carnivalare the most notable earnings reports expected on Tuesday morning.Check out this evening's top movers from around Wall Street, compiled by The Fly.HIGHER AFTER EARNINGS -Sangoma Technologiesup 37.3%IDT Corporationup 4.2%ALSO HIGHER -Summit Therapeuticsup 18.5% after AstraZenecainvestment of $2.0BAAR Corp.up 2.5% after agreement to acquire 65% interest in MRO Holdings for $1.8B and Q1 pre-announcementNeurocrine Biosciencesup 2.0% after naming new Chief Medical OfficerGen Digitalup 1.6% after positive Q2 pre-announcementRTX Corporationup 1.0% after being awarded $20.7B U.S. Air Force multi-year contractDOWN AFTER EARNINGS -Vail Resortsdown 2.0%Jefferies Financialdown 1.4%ReposiTrakdown 1.2%
Neurocrine Biosciences Appoints Eiry Roberts as Chief Medical Officer
Neurocrine Biosciences announced that Eiry Roberts, M.D., who previously served as Neurocrine's Chief Medical Officer and currently serves as a Strategic Advisor, will rejoin the company's executive management team as Chief Medical Officer, effective immediately. By mutual agreement, Sanjay Keswani, M.D., will depart the company. Dr. Roberts served as Neurocrine's Chief Medical Officer from 2018 to 2025 and has continued to support the company since that time as a Strategic Advisor.
Trump Considers New Semiconductor Tariffs Impacting Multiple Companies
Catch up on the top industries and stocks that were impacted, or were predicted to be impacted, by the comments, actions and policies of President Donald Trump with this daily recap compiled by The Fly.SEMICONDUCTOR TARIFFS:The Trump administration is considering broad new semiconductor tariffs that could extend to chip-containing products such as laptops and data-center servers, potentially raising AI infrastructure costs while linking tariff relief to U.S. manufacturing investment, Politico's Ari Hawkins and Gabby Miller. The administration is also mulling a phase-in period for the new tariffs, people familiar with the matter say. Publicly traded companies in the space include AMD, Intel, Marvell, Microchip, Micron, Nvidia, Qualcommand Texas Instruments.GRID EQUIPMENT:President Trump signed an emergency order that bars the U.S. purchase or installation of certain foreign-made, bulk-power system electrical equipment, and associated software, where it could pose cybersecurity or operational risks, Jennifer Dlouhy of Bloomberg, citing a White House official. Publicly traded companies in the solar space include Array Technologies, Canadian Solar, Emeren, Enphase Energy, FTC Solar, First Solar, JinkoSolar, Maxeon Solar, Shoals Technologies, SolarEdge, SunPowerand Sunrun.DRUG PRICING DEALS:The Trump administration is set to announce new drug pricing agreements with several midsized biotechs, trading Medicaid discounts tied to international prices for exemptions from certain Medicare pricing pilots and, in some cases, tariff relief, Bloomberg's Nyah Phengsitthy, Rachel Cohrs Zhang, and Madison Muller. Publicly traded companies in the space include Neurocrine Biosciences, Exelixis, Alnylam, BioMarin, United Therapeutics, Ionis, Bio-Techne, and Alkermes.DATA-SHARING DEALS:The Trump administration has struck data-sharing deals with OpenAI, Google, Meta, Amazon, and other tech companies to track how AI is affecting jobs and hiring, Courtenay Brown of Axios. The Labor Department has signed memorandums of understanding with "a lot of these tech companies," acting Labor Secretary Keith Sonderling told Axios.
Neurocrine Publishes KINECT-PRO Study Results, INGREZZA Significantly Improves Patient Quality of Life
Neurocrine Biosciences announced publication of the KINECT-PRO Phase 4 open-label study results demonstrating that treatment with once-daily INGREZZA, or valbenazine, capsules resulted in substantial and sustained improvements in patient-reported quality of life and functionality, alongside improvements in clinician-rated tardive dyskinesia, or TD, movement severity. Improvements were observed regardless of underlying psychiatric diagnosis or baseline TD movement severity, including among participants with clinician-rated mild TD movements. The manuscript appears in CNS Spectrums. KINECT-PRO is currently the only study to assess the effects of a vesicular monoamine transporter 2, or VMAT2, inhibitor (INGREZZA) on quality of life and functionality using multiple validated patient-reported outcomes, including the Tardive Dyskinesia Impact Scale, developed by Neurocrine Biosciences in partnership with thought leaders in neurology and psychiatry, is a unique, psychometrically validated tool that measures the impact and burden of TD from a patient's perspective. Together with clinician-rated assessments, these findings provide a more comprehensive understanding of how treatment may affect both TD movements and the impact of the disease on patients' daily lives. The primary endpoints of KINECT-PRO were changes from baseline to Week 24 in three validated patient-reported measures of quality of life and functionality. KINECT-PRO participants experienced substantial improvements across the three validated patient-reported measures of quality of life, as well as improvements in clinician-reported TD severity. Mean improvements in TD impact and movement severity exceeded established minimal clinically important difference thresholds as early as Week 8 and Week 4, respectively, and were sustained to Week 24. Improvements were observed regardless of underlying psychiatric condition or TD movement severity at baseline. Even patients with milder clinician-rated TD movement severity were impacted by TD at baseline and experienced clinically meaningful improvements by Week 24, including a -6.8 mean change from baseline in TDIS and a -5.6 mean change from baseline in AIMS. Approximately 58% of patients met the threshold for TD symptomatic remission at Week 24, defined as a movement severity score of 0 or 1 in each of the seven body regions assessed by AIMS. Safety and tolerability of treatment were consistent with the known profile of INGREZZA, with no new concerns identified.
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