Ionis Pharmaceuticals Inc

Análisis de la acción Ionis Pharmaceuticals Inc (IONS)

$45.400

+1.044 (+2.30%)Al cierre

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Máximo
45.480
Apertura
44.450
Precio medio ponderado por volumen
44.96
Volumen
2.49M
Capitalización
6.89B
Mínimo
44.010
Importe
111.84M
EV/EBITDA, TTM
-18.48

Ionis Pharmaceuticals, Inc. develops six marketed medicines for serious diseases, including medicines for neurologic and cardiovascular diseases. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis.

www.ionis.com

Análisis de IA of Ionis Pharmaceuticals Inc (IONS)

Mantener

Ionis Pharmaceuticals is currently not a strong buy. The stock is trading at $42.94, which is significantly below its 200-day simple moving average of $68.60, indicating a bearish trend. Additionally, the RSI is at 41.83, suggesting that the stock is nearing oversold territory but not yet a clear buy signal. The forward P/E ratio is extremely high at 90.91, indicating that the stock may be overvalued based on future earnings expectations. Furthermore, the company reported a significant year-to-date decline of 46.10%, which raises concerns about its short-term performance. The main risk is the recent negative sentiment reflected in analyst downgrades and competitive pressures, particularly from Alnylam, which reported a 41% revenue decline for Ionis compared to its own 74% growth.

Recomendaciones de analistas (15)

+104.12% de potencial alcista
Mantener
5 Comprar
8 Mantener
2 Vender
Actual: 45.40
Mínimo
65.00
Promedio
92.67
Máximo
110.00

JPMorgan

2026-09-22

Precio objetivo

$70

Sobreponderar

Guggenheim

2026-09-15

Precio objetivo

$80

Comprar

Barclays

2026-09-09

Precio objetivo

$85

Sobreponderar

Raymond James

2026-09-08

Precio objetivo

$84

Superar al mercado

Morgan Stanley

2026-09-08

Precio objetivo

$104

Sobreponderar

Métricas de valoración

El PER previsto actual de Ionis Pharmaceuticals Inc (IONS) es 90.91, frente a su media de 5 años de 1.06.

PER previsto

Muy sobrevalorado
Media 5A P/E
1.06
P/E actual
90.91
Sobrevalorada
41.53
Infravalorada
-39.41

EV/EBITDA previsto

Valor razonable
Media 5A EV/EBITDA
-13.39
EV/EBITDA actual
-18.48
Sobrevalorada
-7.11
Infravalorada
-19.67

Precio/ventas previsto

Infravalorado
Media 5A P/S
9.46
P/S actual
5.24
Sobrevalorada
11.73
Infravalorada
7.18

Escenarios de precio de Alphio AI para IONS

Los precios por escenario son la última banda de previsión mensual del año en curso. Las probabilidades son pesos fijos del modelo (25 / 50 / 25), no garantías.

A

Alcista

Alcista · 25%IONS

$34.91

Precio del escenario

B

Base

Base · 50%IONS

$28.85

Precio del escenario

B

Bajista

Bajista · 25%IONS

$20.89

Precio del escenario

Ballenas con IONS en cartera

G

Groupama Asset Management SA

+ Con en carteraIONS

+4.12%

Rentabilidad a 3 meses

P

Pictet Asset Management (Europe) S.A.

+ Con en carteraIONS

+1.50%

Rentabilidad a 3 meses

T

Tweedy, Browne Company LLC

+ Con en carteraIONS

+1.41%

Rentabilidad a 3 meses

B

Bellevue Asset Management AG

+ Con en carteraIONS

+0.71%

Rentabilidad a 3 meses

B

Bluebox Asset Management Uk Ltd.

+ Con en carteraIONS

-0.97%

Rentabilidad a 3 meses

D

Deerfield Management Company, L.P.

+ Con en carteraIONS

-6.89%

Rentabilidad a 3 meses

Cronología de eventos

2026-10-16 (ET)

07:00:00

Ionis Pharmaceuticals Receives Positive EU Opinion for Tryngolza in Severe Hypertriglyceridemia

2026-09-23 (ET)

06:00:00

Genentech Reports Positive Interim Results in IgA Nephropathy Study

2026-09-22 (ET)

08:30:00

Ionis and Otsuka Announce FUSION Trial Results

2026-09-04 (ET)

17:00:00

Novartis Announces Ionis' Pelacarsen Trial Did Not Meet Primary Endpoint

Noticias

Preguntas frecuentes sobre IONS, respondidas por Alphio AI

Ionis Pharmaceuticals, Inc. develops six marketed medicines for serious diseases, including medicines for neurologic and cardiovascular diseases. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Ionis Pharmaceuticals is currently not a strong buy. The stock is trading at $42.94, which is significantly below its 200-day simple moving average of $68.60, indicating a bearish trend. Additionally, the RSI is at 41.83, suggesting that the stock is nearing oversold territory but not yet a clear buy signal. The forward P/E ratio is extremely high at 90.91, indicating that the stock may be overvalued based on future earnings expectations. Furthermore, the company reported a significant year-to-date decline of 46.10%, which raises concerns about its short-term performance. The main risk is the recent negative sentiment reflected in analyst downgrades and competitive pressures, particularly from Alnylam, which reported a 41% revenue decline for Ionis compared to its own 74% growth.

15 analysts cover IONS: 5 rate it Buy, 8 Hold and 2 Sell. The average price target is 92.67.

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