Denali Therapeutics Inc

Análisis de la acción Denali Therapeutics Inc (DNLI)

$23.760

-0.238 (-1.00%)Al cierre

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High
24.010
Open
23.720
VWAP
23.73
Vol
985.86K
Mkt Cap
3.28B
Low
23.411
Amount
23.39M
EV/EBITDA, TTM
-0.80

Denali Therapeutics Inc. is a biopharmaceutical company establishing a new class of biotherapeutics designed to cross the blood-brain barrier using its TransportVehicle platform. It is focused on building a portfolio of therapeutic candidates by investing in its TV franchises, i.e., Enzyme TV (ETV), Oligonucleotide TV (OTV), and Antibody TV (ATV), to advance programs for rare diseases, such as lysosomal storage diseases, and common diseases, such as Alzheimer's disease and Parkinson's disease. Its most advanced TV-enabled program is tividenofusp alfa (DNL310, ETV:IDS) for the potential treatment of mucopolysaccharidosis II (Hunter syndrome). TV-enabled clinical development portfolio also includes DNL126 (ETV:SGSH) for mucopolysaccharidosis IIIA (Sanfilippo syndrome type A), DNL593 (PTV:PGRN) for frontotemporal dementia-granulin, DNL628 (OTV:MAPT) for Alzheimer’s disease, and DNL952 (ETV:GAA) for Pompe disease. It is also pursuing opportunities in other disease areas including oncology.

AI analysis of Denali Therapeutics Inc (DNLI)

buy

Denali Therapeutics Inc (DNLI) is a good buy right now due to its recent revenue growth of $3.6 million in Q2 2026, which exceeded expectations by $1.41 million, and a gross margin of 76.61%, indicating strong profitability potential. However, the main risk is the negative net income margin of -3539.21%, which reflects ongoing losses that investors should consider.

Analyst Ratings (4)

+37.96% upside
Buy
3 Buy
1 Hold
0 Sell
Current: 23.76
Mínimo
25.00
Promedio
32.78
Máximo
40.00

B. Riley

2026-08-25

Precio objetivo

$35

Buy

Morgan Stanley

2026-07-23

Precio objetivo

$36

Overweight

Deutsche Bank

2026-07-16

Precio objetivo

$35

Buy

Morgan Stanley

2026-05-14

Precio objetivo

$40

Overweight

Wedbush

2026-05-08

Precio objetivo

$23

Outperform

Métricas de valoración

The current forward P/E ratio for Denali Therapeutics Inc (DNLI) is 0.00, compared to its 5-year average forward P/E of -10.30.

Forward P/E

Overvalued
5Y Average P/E
-10.30
Current P/E
0.00
Sobrevalorada
-4.20
Infravalorada
-16.39

Forward EV/EBITDA

Overvalued
5Y Average EV/EBITDA
-7.22
Current EV/EBITDA
-0.80
Sobrevalorada
-2.25
Infravalorada
-12.20

Forward P/S

Fair
5Y Average P/S
66.31
Current P/S
29.93
Sobrevalorada
116.91
Infravalorada
15.71

Whales holding DNLI

B

Baker Bros. Advisors LP

+ HoldingDNLI

+24.92%

3M Return

A

Artal Group S.A.

+ HoldingDNLI

+15.85%

3M Return

A

ADAR1 Capital Management, LLC

+ HoldingDNLI

+1.71%

3M Return

C

Crestline Investors Inc.

+ HoldingDNLI

+1.14%

3M Return

Cronología de eventos

2026-07-14 (ET)

12:30:00

Denali Therapeutics Shares Down 14.1% to $22.75

10:30:00

Denali Therapeutics Stock Falls 12.4% to $23.20

2026-06-18 (ET)

08:30:00

Denali Therapeutics Sells Rare Pediatric Disease PRV for $195M

2026-05-21 (ET)

18:10:00

Biogen and Denali Discontinue BIIB122 Development

Noticias

DNLI FAQ — answered by Alphio AI

Denali Therapeutics Inc. is a biopharmaceutical company establishing a new class of biotherapeutics designed to cross the blood-brain barrier using its TransportVehicle platform. It is focused on building a portfolio of therapeutic candidates by investing in its TV franchises, i.e., Enzyme TV (ETV), Oligonucleotide TV (OTV), and Antibody TV (ATV), to advance programs for rare diseases, such as lysosomal storage diseases, and common diseases, such as Alzheimer's disease and Parkinson's disease. Its most advanced TV-enabled program is tividenofusp alfa (DNL310, ETV:IDS) for the potential treatment of mucopolysaccharidosis II (Hunter syndrome). TV-enabled clinical development portfolio also includes DNL126 (ETV:SGSH) for mucopolysaccharidosis IIIA (Sanfilippo syndrome type A), DNL593 (PTV:PGRN) for frontotemporal dementia-granulin, DNL628 (OTV:MAPT) for Alzheimer’s disease, and DNL952 (ETV:GAA) for Pompe disease. It is also pursuing opportunities in other disease areas including oncology. It operates in the Healthcare sector (BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES) industry).

Denali Therapeutics Inc (DNLI) is a good buy right now due to its recent revenue growth of $3.6 million in Q2 2026, which exceeded expectations by $1.41 million, and a gross margin of 76.61%, indicating strong profitability potential. However, the main risk is the negative net income margin of -3539.21%, which reflects ongoing losses that investors should consider.

4 analysts cover DNLI: 3 rate it Buy, 1 Hold and 0 Sell. The average price target is 32.78.

Esta página es solo para investigación y no constituye asesoramiento de inversión. Los modelos pueden equivocarse. El rendimiento pasado no garantiza resultados futuros.

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