Apellis Pharmaceuticals Inc

Apellis Pharmaceuticals Inc (APLS) Stock Analysis

$41.030

-0.029 (-0.07%)At close

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High
41.070
Open
41.050
VWAP
41.04
Vol
68.61M
Mkt Cap
5.04B
Low
41.030
Amount
2.82B
EV/EBITDA, TTM
52.52

Apellis Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on the discovery, development and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system. SYFOVRE (pegcetacoplan injection) is the Company’s approved treatment for geographic atrophy secondary to age-related macular degeneration (GA). Its EMPAVELI (pegcetacoplan) is for the treatment of paroxysmal nocturnal hemoglobinuria (PNH). Its Aspaveli (pegcetacoplan) for the treatment of adults with PNH who are anemic after treatment with a C5 inhibitor for at least three months. Systemic pegcetacoplan has also been approved for the treatment of PNH in Japan, Saudi Arabia, Australia, the United Kingdom and other jurisdictions. Systemic pegcetacoplan is marketed under the trade name EMPAVELI in the United States, Saudi Arabia and Australia and Aspaveli in the European Union, Japan and the United Kingdom.

apellis.com

Analyst Ratings (3)

-22.76% downside
Buy
3 Buy
0 Hold
0 Sell
Current: 41.03
Low
19.00
Average
31.69
High
48.00

Wells Fargo

2026-04-17

Price Target

$41

Equal Weight

RBC Capital

2026-04-07

Price Target

$41

Sector Perform

Mizuho

2026-04-02

Price Target

$41

Neutral

Roth Capital

2026-04-02

Price Target

$41

Neutral

JPMorgan

2026-04-01

Price Target

$41

Neutral

Valuation Metrics

The current forward P/E ratio for Apellis Pharmaceuticals Inc (APLS) is 46.30, compared to its 5-year average forward P/E of -24.34.

Forward P/E

Overvalued
5Y Average P/E
-24.34
Current P/E
46.30
Overvalued
13.68
Undervalued
-62.35

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-17.99
Current EV/EBITDA
52.52
Overvalued
116.16
Undervalued
-152.14

Forward P/S

Fair
5Y Average P/S
19.07
Current P/S
5.11
Overvalued
38.21
Undervalued
-0.07

Alphio AI Price Scenarios for APLS

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%APLS

$26.85

Scenario price

B

Base

Base · 50%APLS

$21.26

Scenario price

B

Bear

Bear · 25%APLS

$19.33

Scenario price

Whales holding APLS

R

RTW Investments, LP

+ HoldingAPLS

+15.57%

3M Return

A

Avoro Capital Advisors LLC

+ HoldingAPLS

+13.10%

3M Return

O

OrbiMed Advisors LLC

+ HoldingAPLS

+5.01%

3M Return

S

Suvretta Capital Management, LLC

+ HoldingAPLS

+2.26%

3M Return

A

Artal Group S.A.

+ HoldingAPLS

-0.61%

3M Return

D

Deep Track Capital, LP

+ HoldingAPLS

-3.79%

3M Return

Events Timeline

2026-08-11 (ET)

08:00:00

Kailera Therapeutics Appoints Nur Nicholson as CTO

2026-05-14 (ET)

09:00:00

Biogen Completes Acquisition of Apellis Pharmaceuticals

2026-05-07 (ET)

17:30:00

Remitly Global to Replace Apellis Pharmaceuticals

2026-04-29 (ET)

06:10:00

Biogen Reports Q1 Revenue of $2.48B, Exceeding Expectations

2026-04-01 (ET)

05:40:00

Raymond James Downgrades Apellis to Market Perform

News

APLS FAQ — answered by Alphio AI

Apellis Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on the discovery, development and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system. SYFOVRE (pegcetacoplan injection) is the Company’s approved treatment for geographic atrophy secondary to age-related macular degeneration (GA). Its EMPAVELI (pegcetacoplan) is for the treatment of paroxysmal nocturnal hemoglobinuria (PNH). Its Aspaveli (pegcetacoplan) for the treatment of adults with PNH who are anemic after treatment with a C5 inhibitor for at least three months. Systemic pegcetacoplan has also been approved for the treatment of PNH in Japan, Saudi Arabia, Australia, the United Kingdom and other jurisdictions. Systemic pegcetacoplan is marketed under the trade name EMPAVELI in the United States, Saudi Arabia and Australia and Aspaveli in the European Union, Japan and the United Kingdom. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

3 analysts cover APLS: 3 rate it Buy, 0 Hold and 0 Sell. The average price target is 31.69.

Diese Seite dient nur der Recherche und ist keine Anlageberatung. Modelle können falsch liegen. Vergangene Wertentwicklung ist kein Indikator für die Zukunft.

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