Denali Therapeutics Inc

Denali Therapeutics Inc(DNLI)股票分析

$24.000

-0.653 (-2.72%)收盘时

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High
24.615
Open
24.420
VWAP
24.18
Vol
807.60K
Mkt Cap
3.28B
Low
23.920
Amount
19.53M
EV/EBITDA, TTM
-0.80

Denali Therapeutics Inc. is a biopharmaceutical company establishing a new class of biotherapeutics designed to cross the blood-brain barrier using its TransportVehicle platform. It is focused on building a portfolio of therapeutic candidates by investing in its TV franchises, i.e., Enzyme TV (ETV), Oligonucleotide TV (OTV), and Antibody TV (ATV), to advance programs for rare diseases, such as lysosomal storage diseases, and common diseases, such as Alzheimer's disease and Parkinson's disease. Its most advanced TV-enabled program is tividenofusp alfa (DNL310, ETV:IDS) for the potential treatment of mucopolysaccharidosis II (Hunter syndrome). TV-enabled clinical development portfolio also includes DNL126 (ETV:SGSH) for mucopolysaccharidosis IIIA (Sanfilippo syndrome type A), DNL593 (PTV:PGRN) for frontotemporal dementia-granulin, DNL628 (OTV:MAPT) for Alzheimer’s disease, and DNL952 (ETV:GAA) for Pompe disease. It is also pursuing opportunities in other disease areas including oncology.

AI analysis of Denali Therapeutics Inc (DNLI)

buy

Denali Therapeutics Inc (DNLI) is a good buy right now due to its recent revenue growth of $3.6 million in Q2 2026, which exceeded expectations by $1.41 million, and a gross margin of 76.61%, indicating strong profitability potential. However, the main risk is the negative net income margin of -3539.21%, which reflects ongoing losses that investors should consider.

Analyst Ratings (4)

+36.58% upside
Buy
3 Buy
1 Hold
0 Sell
Current: 24.00
最低
25.00
平均
32.78
最高
40.00

B. Riley

2026-08-25

目标价

$35

Buy

Morgan Stanley

2026-07-23

目标价

$36

Overweight

Deutsche Bank

2026-07-16

目标价

$35

Buy

Morgan Stanley

2026-05-14

目标价

$40

Overweight

Wedbush

2026-05-08

目标价

$23

Outperform

估值指标

The current forward P/E ratio for Denali Therapeutics Inc (DNLI) is 0.00, compared to its 5-year average forward P/E of -10.31.

Forward P/E

Overvalued
5Y Average P/E
-10.31
Current P/E
0.00
高估
-4.20
低估
-16.41

Forward EV/EBITDA

Overvalued
5Y Average EV/EBITDA
-7.24
Current EV/EBITDA
-0.80
高估
-2.25
低估
-12.24

Forward P/S

Fair
5Y Average P/S
66.33
Current P/S
30.23
高估
116.92
低估
15.74

Whales holding DNLI

B

Baker Bros. Advisors LP

+ HoldingDNLI

+18.95%

3M Return

A

ADAR1 Capital Management, LLC

+ HoldingDNLI

+2.25%

3M Return

C

Crestline Investors Inc.

+ HoldingDNLI

+1.85%

3M Return

A

Artal Group S.A.

+ HoldingDNLI

-0.61%

3M Return

事件时间线

2026-07-14 (ET)

12:30:00

Denali Therapeutics Shares Down 14.1% to $22.75

10:30:00

Denali Therapeutics Stock Falls 12.4% to $23.20

2026-06-18 (ET)

08:30:00

Denali Therapeutics Sells Rare Pediatric Disease PRV for $195M

2026-05-21 (ET)

18:10:00

Biogen and Denali Discontinue BIIB122 Development

资讯

DNLI FAQ — answered by Alphio AI

Denali Therapeutics Inc. is a biopharmaceutical company establishing a new class of biotherapeutics designed to cross the blood-brain barrier using its TransportVehicle platform. It is focused on building a portfolio of therapeutic candidates by investing in its TV franchises, i.e., Enzyme TV (ETV), Oligonucleotide TV (OTV), and Antibody TV (ATV), to advance programs for rare diseases, such as lysosomal storage diseases, and common diseases, such as Alzheimer's disease and Parkinson's disease. Its most advanced TV-enabled program is tividenofusp alfa (DNL310, ETV:IDS) for the potential treatment of mucopolysaccharidosis II (Hunter syndrome). TV-enabled clinical development portfolio also includes DNL126 (ETV:SGSH) for mucopolysaccharidosis IIIA (Sanfilippo syndrome type A), DNL593 (PTV:PGRN) for frontotemporal dementia-granulin, DNL628 (OTV:MAPT) for Alzheimer’s disease, and DNL952 (ETV:GAA) for Pompe disease. It is also pursuing opportunities in other disease areas including oncology. It operates in the Healthcare sector (BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES) industry).

Denali Therapeutics Inc (DNLI) is a good buy right now due to its recent revenue growth of $3.6 million in Q2 2026, which exceeded expectations by $1.41 million, and a gross margin of 76.61%, indicating strong profitability potential. However, the main risk is the negative net income margin of -3539.21%, which reflects ongoing losses that investors should consider.

4 analysts cover DNLI: 3 rate it Buy, 1 Hold and 0 Sell. The average price target is 32.78.

本页仅供研究参考,不构成投资建议。模型可能出错。过往表现不代表未来结果。

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