Zenas Biopharma Inc

Zenas Biopharma Inc (ZBIO) Stock Analysis

$31.980

-0.336 (-1.05%)At close

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High
32.710
Open
32.500
VWAP
32.10
Vol
432.25K
Mkt Cap
Low
31.620
Amount
13.88M
EV/EBITDA, TTM
-0.53

Zenas BioPharma, Inc. is a clinical-stage global biopharmaceutical company focused on development and commercialization of therapies for patients living with autoimmune diseases. It is advancing two late-stage, potential franchise molecules, obexelimab and orelabrutinib. Obexelimab, its lead product candidate, is a bifunctional monoclonal antibody designed to bind both CD19 and FcgRIIb, which are broadly present across B cell lineage, to inhibit the activity of cells that are implicated in many autoimmune diseases without depleting them. Orelabrutinib is a highly selective central nervous system (CNS)-penetrant, oral, small molecule BTK inhibitor. Orelabrutinib's mechanism of action targets pathogenic B cells not only in periphery but also within CNS. Its earlier stage programs include ZB021, an oral small molecule IL-17AA/AF inhibitor; ZB022, a preclinical, oral, brain-penetrant, TYK2 inhibitor, and ZB014, a preclinical, half-life extended anti-CD19 and FcgRIIb monoclonal antibody.

zenasbio.com

AI analysis of Zenas Biopharma Inc (ZBIO)

buy

Zenas Biopharma Inc is a good buy right now due to its current price of $31.27, which is significantly below the analyst price target of $41 from Citi, indicating a potential upside of 31%. Additionally, the company has a strong cash position of $718.5 million, which supports its operations and upcoming trials. However, the main risk is the negative earnings trend, with a reported EPS of -1.77 in the latest quarter, which reflects ongoing financial challenges.

Valuation Metrics

The current forward P/E ratio for Zenas Biopharma Inc (ZBIO) is 0.00, compared to its 5-year average forward P/E of -4.38.

Forward P/E

Overvalued
5Y Average P/E
-4.38
Current P/E
0.00
Overvalued
-1.14
Undervalued
-7.63

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-1.82
Current EV/EBITDA
-0.53
Overvalued
0.75
Undervalued
-4.39

Forward P/S

Fair
5Y Average P/S
29.85
Current P/S
37.76
Overvalued
63.81
Undervalued
-4.11

Alphio AI Price Scenarios for ZBIO

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%ZBIO

$14.78

Scenario price

B

Base

Base · 50%ZBIO

$13.30

Scenario price

B

Bear

Bear · 25%ZBIO

$11.16

Scenario price

Whales holding ZBIO

F

Fairmount Funds Management LLC

+ HoldingZBIO

+20.87%

3M Return

R

Rock Springs Capital Management LP

+ HoldingZBIO

+19.26%

3M Return

Events Timeline

2026-08-13 (ET)

08:00:00

Jennifer Fox to Transition to Strategic Advisor Role

08:00:00

Zenas Reports Q2 Revenue of $1M, Below Consensus of $15M

2026-05-28 (ET)

07:30:00

Zenas BioPharma Submits BLA for Obexelimab to FDA

2026-05-13 (ET)

07:00:00

Zenas BioPharma Doses First Subject in Phase 1 Trial of ZB021

06:10:00

Zenas Reports Q1 Revenue of $0, Cash Reserves at $718.5M

News

ZBIO FAQ — answered by Alphio AI

Zenas BioPharma, Inc. is a clinical-stage global biopharmaceutical company focused on development and commercialization of therapies for patients living with autoimmune diseases. It is advancing two late-stage, potential franchise molecules, obexelimab and orelabrutinib. Obexelimab, its lead product candidate, is a bifunctional monoclonal antibody designed to bind both CD19 and FcgRIIb, which are broadly present across B cell lineage, to inhibit the activity of cells that are implicated in many autoimmune diseases without depleting them. Orelabrutinib is a highly selective central nervous system (CNS)-penetrant, oral, small molecule BTK inhibitor. Orelabrutinib's mechanism of action targets pathogenic B cells not only in periphery but also within CNS. Its earlier stage programs include ZB021, an oral small molecule IL-17AA/AF inhibitor; ZB022, a preclinical, oral, brain-penetrant, TYK2 inhibitor, and ZB014, a preclinical, half-life extended anti-CD19 and FcgRIIb monoclonal antibody. It operates in the Healthcare sector.

Zenas Biopharma Inc is a good buy right now due to its current price of $31.27, which is significantly below the analyst price target of $41 from Citi, indicating a potential upside of 31%. Additionally, the company has a strong cash position of $718.5 million, which supports its operations and upcoming trials. However, the main risk is the negative earnings trend, with a reported EPS of -1.77 in the latest quarter, which reflects ongoing financial challenges.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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