Xencor Inc

Xencor Inc (XNCR) Stock Analysis

$22.850

-1.095 (-4.79%)At close

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High
24.210
Open
24.020
VWAP
23.27
Volume
1.13M
Mkt Cap
1.18B
Low
22.760
Amount
26.30M
EV/EBITDA, TTM
-23.18

Xencor, Inc. is a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases. It has more than 20 candidates engineered with its XmAb technology that are in clinical development, and multiple XmAb medicines are marketed by partners. Its XmAb engineering technology enables small changes to a protein structure that result in new mechanisms of therapeutic action. Its wholly-owned development candidates include XmAb942, XmAb819, XmAb808, and XmAb541. Candidates co-developed with partners include Plamotamab. Its clinical-stage drug candidates advanced by partners include Xaluritamig (AMG 509), ASP2138, JNJ-9401, JNJ-1493, Xpro1595, Obexelimab, and Novartis XmAb, an undisclosed antibody candidate. Its cytokine drug candidates in clinical development consist of efbalropendekin alfa (XmAb306/RG6323). Its Vudalimab is a bispecific antibody that targets PD-1 and CTLA-4.

xencor.com

AI analysis of Xencor Inc (XNCR)

Hold

Xencor Inc is currently not a strong buy due to its low RSI of 31.176, indicating oversold conditions, and a significant forward P/E ratio of 68.03, suggesting high valuation expectations. However, the stock has shown a year-to-date change of +53.15%, indicating strong performance over the year. The main risk is the recent 5-day change of -7.23%, which reflects downward momentum in the short term.

Analyst Ratings (5)

+14.88% upside
Buy
4 Buy
1 Hold
0 Sell
Current: 22.85
Low
20.00
Average
26.25
High
30.00

Truist

2026-09-28

Price Target

$29

Buy

BofA

2026-09-21

Price Target

$26

Neutral

Barclays

2026-09-11

Price Target

$35

Overweight

JPMorgan

2026-09-03

Price Target

$21

Neutral

Raymond James

2026-09-01

Price Target

$46

Strong Buy

Valuation Metrics

The current forward P/E ratio for Xencor Inc (XNCR) is 68.03, compared to its 5-year average forward P/E of 3.32.

Forward P/E

Strongly Overvalued
5Y Average P/E
3.32
Current P/E
68.03
Overvalued
32.14
Undervalued
-25.50

Forward EV/EBITDA

Undervalued
5Y Average EV/EBITDA
-4.04
Current EV/EBITDA
-23.18
Overvalued
12.64
Undervalued
-20.73

Forward P/S

Fair
5Y Average P/S
12.83
Current P/S
14.67
Overvalued
18.28
Undervalued
7.38

Alphio AI Price Scenarios for XNCR

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%XNCR

$11.91

Scenario price

B

Base

Base · 50%XNCR

$10.33

Scenario price

B

Bear

Bear · 25%XNCR

$9.17

Scenario price

Whales holding XNCR

R

RTW Investments, LP

+ HoldingXNCR

-11.31%

3M Return

R

RA Capital Management, L.P.

+ HoldingXNCR

-26.36%

3M Return

T

TCG Crossover Management, LLC

+ HoldingXNCR

-28.85%

3M Return

XNCR FAQ — answered by Alphio AI

Xencor, Inc. is a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases. It has more than 20 candidates engineered with its XmAb technology that are in clinical development, and multiple XmAb medicines are marketed by partners. Its XmAb engineering technology enables small changes to a protein structure that result in new mechanisms of therapeutic action. Its wholly-owned development candidates include XmAb942, XmAb819, XmAb808, and XmAb541. Candidates co-developed with partners include Plamotamab. Its clinical-stage drug candidates advanced by partners include Xaluritamig (AMG 509), ASP2138, JNJ-9401, JNJ-1493, Xpro1595, Obexelimab, and Novartis XmAb, an undisclosed antibody candidate. Its cytokine drug candidates in clinical development consist of efbalropendekin alfa (XmAb306/RG6323). Its Vudalimab is a bispecific antibody that targets PD-1 and CTLA-4. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Xencor Inc is currently not a strong buy due to its low RSI of 31.176, indicating oversold conditions, and a significant forward P/E ratio of 68.03, suggesting high valuation expectations. However, the stock has shown a year-to-date change of +53.15%, indicating strong performance over the year. The main risk is the recent 5-day change of -7.23%, which reflects downward momentum in the short term.

5 analysts cover XNCR: 4 rate it Buy, 1 Hold and 0 Sell. The average price target is 26.25.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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