Xeris Biopharma Holdings Inc

Xeris Biopharma Holdings Inc (XERS) Stock Analysis

$10.950

+0.680 (+6.21%)At close

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High
11.415
Open
10.340
VWAP
10.90
Volume
4.34M
Mkt Cap
335.06M
Low
10.340
Amount
47.35M
EV/EBITDA, TTM
51.66

Xeris Biopharma Holdings, Inc. is a biopharmaceutical company focused on improving patient lives by developing and commercializing products across a range of therapies. It has three commercially available products: Recorlev, Gvoke, and Keveyis. Recorlev is for the treatment of endogenous Cushing’s syndrome. Gvoke is a ready-to-use liquid glucagon for the treatment of severe hypoglycemia. Keveyis is a therapy for primary periodic paralysis. It also has a pipeline of development programs led by XP-8121, a phase III-ready, once-weekly subcutaneous injection for hypothyroidism. It is pursuing formulation and development partnerships to apply its XeriSol and XeriJect formulation technologies to enhance the drug delivery and clinical profile of other companies’ proprietary drugs and biologics. Recorlev is a cortisol synthesis inhibitor approved for the treatment of endogenous hypercortisolemia in adults with Cushing's syndrome for whom surgery is not an option or has not been curative.

AI analysis of Xeris Biopharma Holdings Inc (XERS)

Buy

Xeris Biopharma (XERS) is a good buy right now due to its current price of $10.31 being significantly below the analyst price target of $14 to $16, indicating a potential upside of 36% to 55%. Additionally, the company has shown strong revenue growth, with Q2 2026 revenue reaching $92.1 million, a 29% year-over-year increase, and a gross margin of 83.47%, which reflects efficient operations. However, a risk to consider is the recent net loss of $31 million in Q2 2026, which could impact investor sentiment.

Analyst Ratings (4)

-11.69% Downside
Buy
4 Buy
0 Hold
0 Sell
Current: 10.95
Low
9.00
Average
9.67
High
10.00

Barclays

2026-10-06

Price Target

$14

Overweight

Leerink

2026-09-10

Price Target

$16

Outperform

Barclays

2026-08-20

Price Target

$12

Overweight

Barclays

2025-12-08

Price Target

$9

Overweight

Piper Sandler

2025-11-07

Price Target

$8

Neutral

Valuation Metrics

The current forward P/E ratio for Xeris Biopharma Holdings Inc (XERS) is 36.90, compared to its 5-year average forward P/E of 6.81.

Forward P/E

Fair
5Y Average P/E
6.81
Current P/E
36.90
Overvalued
56.28
Undervalued
-42.67

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-7.72
Current EV/EBITDA
51.66
Overvalued
94.49
Undervalued
-109.93

Forward P/S

Strongly Overvalued
5Y Average P/S
2.24
Current P/S
3.92
Overvalued
3.00
Undervalued
1.49

Alphio AI Price Scenarios for XERS

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%XERS

$6.84

Scenario price

B

Base

Base · 50%XERS

$5.94

Scenario price

B

Bear

Bear · 25%XERS

$5.31

Scenario price

Whales holding XERS

V

Voss Capital, LP

+ HoldingXERS

-4.32%

3M Return

Events Timeline

2026-10-15 (ET)

08:30:00

Xeris Biopharma Presents Clinical Data at Three Major Meetings

2026-09-29 (ET)

17:00:00

Major Averages Decline as 30-Year Bond Yield Hits Highest Level Since 2002

13:00:00

Lundbeck Interested in Acquiring Xeris Biopharma

13:00:00

Lundbeck Interested in Acquiring Xeris

13:00:00

Xeris Stock Jumps 13% to $11.12 on Lundbeck Interest Report

News

XERS FAQ — answered by Alphio AI

Xeris Biopharma Holdings, Inc. is a biopharmaceutical company focused on improving patient lives by developing and commercializing products across a range of therapies. It has three commercially available products: Recorlev, Gvoke, and Keveyis. Recorlev is for the treatment of endogenous Cushing’s syndrome. Gvoke is a ready-to-use liquid glucagon for the treatment of severe hypoglycemia. Keveyis is a therapy for primary periodic paralysis. It also has a pipeline of development programs led by XP-8121, a phase III-ready, once-weekly subcutaneous injection for hypothyroidism. It is pursuing formulation and development partnerships to apply its XeriSol and XeriJect formulation technologies to enhance the drug delivery and clinical profile of other companies’ proprietary drugs and biologics. Recorlev is a cortisol synthesis inhibitor approved for the treatment of endogenous hypercortisolemia in adults with Cushing's syndrome for whom surgery is not an option or has not been curative. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Xeris Biopharma (XERS) is a good buy right now due to its current price of $10.31 being significantly below the analyst price target of $14 to $16, indicating a potential upside of 36% to 55%. Additionally, the company has shown strong revenue growth, with Q2 2026 revenue reaching $92.1 million, a 29% year-over-year increase, and a gross margin of 83.47%, which reflects efficient operations. However, a risk to consider is the recent net loss of $31 million in Q2 2026, which could impact investor sentiment.

4 analysts cover XERS: 4 rate it Buy, 0 Hold and 0 Sell. The average price target is 9.67.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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