Xenon Pharmaceuticals Inc

Xenon Pharmaceuticals Inc (XENE) Stock Analysis

$34.330

+0.436 (+1.27%)At close

Loading chart…
High
34.990
Open
34.100
VWAP
34.46
Volume
1.62M
Mkt Cap
2.82B
Low
34.050
Amount
55.74M
EV/EBITDA, TTM
0.00

Xenon Pharmaceuticals Inc. is a Canada-based neuroscience-focused biopharmaceutical company committed to discovering, developing, and commercializing therapeutics to improve the lives of people living with neurological and psychiatric disorders. The Company is advancing a novel product pipeline to address areas of high unmet medical need, including epilepsy and depression. Azetukalner, a novel, highly potent, selective Kv7 potassium channel opener, represents the advanced, clinically validated potassium channel modulator in late-stage clinical development for the treatment of multiple indications that include epilepsy, including focal onset seizures (FOS), and primary generalized tonic-clonic seizures (PGTCS), as well as neuropsychiatric disorders including major depressive disorder (MDD), and bipolar depression (BPD). The Company is evaluating multiple therapeutic candidates targeting Kv7, Nav1.7, and Nav1.1 across various indications.

AI analysis of Xenon Pharmaceuticals Inc (XENE)

Hold

Xenon Pharmaceuticals Inc is currently not a good buy due to significant recent volatility and negative sentiment surrounding its clinical trials. The stock has dropped 25% recently due to a pause in new patient enrollment for clinical studies, which raises concerns about its future growth. While the stock is currently priced at $36.44, analysts have set price targets as high as $73, indicating potential upside, but the recent RSI of 27.531 suggests it is oversold. The main risk is the ongoing uncertainty in clinical trials, particularly with a net loss of $110.7 million reported in Q2 2026, which could impact investor confidence.

Analyst Ratings (3)

+57.56% upside
Buy
3 Buy
0 Hold
0 Sell
Current: 34.33
Low
44.00
Average
54.09
High
62.00

Guggenheim

2026-10-05

Price Target

$73

Buy

TD Cowen

2026-09-18

Price Target

$42.30

Buy

Baird

2026-09-18

Price Target

$90

Outperform

Needham

2026-09-18

Price Target

$60

Buy

Wells Fargo

2026-09-18

Price Target

$64

Overweight

Valuation Metrics

The current forward P/E ratio for Xenon Pharmaceuticals Inc (XENE) is 0.00, compared to its 5-year average forward P/E of -12.32.

Forward P/E

Strongly Overvalued
5Y Average P/E
-12.32
Current P/E
0.00
Overvalued
-9.72
Undervalued
-14.91

Forward EV/EBITDA

Strongly Overvalued
5Y Average EV/EBITDA
-7.71
Current EV/EBITDA
0.00
Overvalued
-4.26
Undervalued
-11.15

Forward P/S

Fair
5Y Average P/S
2122.21
Current P/S
123.57
Overvalued
5753.30
Undervalued
-1508.87

Whales holding XENE

B

Braidwell LP

+ HoldingXENE

+13.80%

3M Return

P

Polar Capital Holdings Plc

+ HoldingXENE

+2.48%

3M Return

D

Deerfield Management Company, L.P.

+ HoldingXENE

-8.23%

3M Return

R

Rock Springs Capital Management LP

+ HoldingXENE

-11.63%

3M Return

O

OrbiMed Advisors LLC

+ HoldingXENE

-14.89%

3M Return

V

Vestal Point Capital, LP

+ HoldingXENE

-16.91%

3M Return

Events Timeline

2026-10-05 (ET)

19:30:00

Nasdaq Hits Record Highs, S&P 500 Up 0.7%

2026-09-18 (ET)

16:30:00

Middle East War Influences Energy Prices and Markets

12:30:00

Stocks Drop as Treasury Yields Rebound

12:30:00

Xenon Pharmaceuticals Stock Drops 28.9% to $40.75

11:25:00

Xenon Pharmaceuticals Shares Drop 29.8% to $40.27

News

XENE FAQ — answered by Alphio AI

Xenon Pharmaceuticals Inc. is a Canada-based neuroscience-focused biopharmaceutical company committed to discovering, developing, and commercializing therapeutics to improve the lives of people living with neurological and psychiatric disorders. The Company is advancing a novel product pipeline to address areas of high unmet medical need, including epilepsy and depression. Azetukalner, a novel, highly potent, selective Kv7 potassium channel opener, represents the advanced, clinically validated potassium channel modulator in late-stage clinical development for the treatment of multiple indications that include epilepsy, including focal onset seizures (FOS), and primary generalized tonic-clonic seizures (PGTCS), as well as neuropsychiatric disorders including major depressive disorder (MDD), and bipolar depression (BPD). The Company is evaluating multiple therapeutic candidates targeting Kv7, Nav1.7, and Nav1.1 across various indications. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Xenon Pharmaceuticals Inc is currently not a good buy due to significant recent volatility and negative sentiment surrounding its clinical trials. The stock has dropped 25% recently due to a pause in new patient enrollment for clinical studies, which raises concerns about its future growth. While the stock is currently priced at $36.44, analysts have set price targets as high as $73, indicating potential upside, but the recent RSI of 27.531 suggests it is oversold. The main risk is the ongoing uncertainty in clinical trials, particularly with a net loss of $110.7 million reported in Q2 2026, which could impact investor confidence.

3 analysts cover XENE: 3 rate it Buy, 0 Hold and 0 Sell. The average price target is 54.09.

Community

More ↗

No posts yet

Sign up or log in to join the discussion

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

Start trading