Tyra Biosciences Inc

Tyra Biosciences Inc (TYRA) Stock Analysis

$24.940

-1.135 (-4.55%)At close

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High
25.880
Open
25.880
VWAP
25.24
Vol
217.50K
Mkt Cap
811.74M
Low
24.910
Amount
5.49M
EV/EBITDA, TTM
0.00

Tyra Biosciences, Inc. is a clinical-stage biotechnology company focused on developing precision medicines that target opportunities in FGFR biology. Its in-house precision medicine platform, SNAP, enables rapid and precise drug design through iterative molecular SNAPshots that help it design and predict which candidates may demonstrate highest potency, selectivity and tolerability in clinic. Its expertise in FGFR biology has created a pipeline with clinical-stage programs in targeted oncology and genetically defined conditions. Its lead precision medicine stemming from SNAP, oral dabogratinib, is a potential first-in-class selective FGFR3 inhibitor in development for LG-UTUC, IR NMIBC and ACH. It is also developing TYRA-430, an oral, investigational FGFR4/3-biased inhibitor for FGF19+/FGFR4-driven cancers, in SURF431 study (advanced hepatocellular carcinoma), and TYRA-200, an oral, investigational, FGFR1/2/3 inhibitor, in SURF201 study (metastatic intrahepatic cholangiocarcinoma).

tyra.bio

AI analysis of Tyra Biosciences Inc (TYRA)

hold

Tyra Biosciences is currently priced at $24.94, with a recent RSI of 30.448 indicating oversold conditions. However, the company has reported significant net losses, with Q2 2026 EPS at -0.69, missing expectations, and a forward P/E ratio of 0, suggesting uncertainty in future earnings. The analyst price targets range from $39 to $56, indicating potential upside, but the recent insider selling activity has increased by 100.98%, which raises concerns about confidence in the stock. Given these factors, it may be prudent to hold off on buying until there are clearer signs of recovery or stability in earnings.

Valuation Metrics

The current forward P/E ratio for Tyra Biosciences Inc (TYRA) is 0.00, compared to its 5-year average forward P/E of -8.72.

Forward P/E

Overvalued
5Y Average P/E
-8.72
Current P/E
0.00
Overvalued
-4.25
Undervalued
-13.19

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-3.45
Current EV/EBITDA
0.00
Overvalued
12.33
Undervalued
-19.24

Forward P/S

Fair
5Y Average P/S
6489.68
Current P/S
0.00
Overvalued
50591.72
Undervalued
-37612.35

Alphio AI Price Scenarios for TYRA

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%TYRA

$12.90

Scenario price

B

Base

Base · 50%TYRA

$12.01

Scenario price

B

Bear

Bear · 25%TYRA

$10.21

Scenario price

Whales holding TYRA

C

Commodore Capital LP

+ HoldingTYRA

+34.35%

3M Return

S

Sofinnova Investments, Inc.

+ HoldingTYRA

+15.48%

3M Return

B

BVF Partners L.P.

+ HoldingTYRA

+11.78%

3M Return

R

RA Capital Management, L.P.

+ HoldingTYRA

+2.43%

3M Return

T

TCG Crossover Management, LLC

+ HoldingTYRA

-4.24%

3M Return

C

Caligan Partners, LP

+ HoldingTYRA

-6.01%

3M Return

Events Timeline

2026-08-05 (ET)

13:00:00

Stock Down $6.39 to $26.15 in Midday Trading

13:00:00

JonesResearch Maintains Buy Rating on Tyra with $56 Price Target

2026-05-13 (ET)

08:10:00

TYRA Reports $383.5M in Cash and Securities, Advancing Drug Development

2026-04-25 (ET)

19:10:00

Lyft Short Interest Rises to 25.7%

2026-03-02 (ET)

16:30:00

TYRA CEO Emphasizes FGFR3 Importance, Plans $256M Investment

News

TYRA FAQ — answered by Alphio AI

Tyra Biosciences, Inc. is a clinical-stage biotechnology company focused on developing precision medicines that target opportunities in FGFR biology. Its in-house precision medicine platform, SNAP, enables rapid and precise drug design through iterative molecular SNAPshots that help it design and predict which candidates may demonstrate highest potency, selectivity and tolerability in clinic. Its expertise in FGFR biology has created a pipeline with clinical-stage programs in targeted oncology and genetically defined conditions. Its lead precision medicine stemming from SNAP, oral dabogratinib, is a potential first-in-class selective FGFR3 inhibitor in development for LG-UTUC, IR NMIBC and ACH. It is also developing TYRA-430, an oral, investigational FGFR4/3-biased inhibitor for FGF19+/FGFR4-driven cancers, in SURF431 study (advanced hepatocellular carcinoma), and TYRA-200, an oral, investigational, FGFR1/2/3 inhibitor, in SURF201 study (metastatic intrahepatic cholangiocarcinoma). It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Tyra Biosciences is currently priced at $24.94, with a recent RSI of 30.448 indicating oversold conditions. However, the company has reported significant net losses, with Q2 2026 EPS at -0.69, missing expectations, and a forward P/E ratio of 0, suggesting uncertainty in future earnings. The analyst price targets range from $39 to $56, indicating potential upside, but the recent insider selling activity has increased by 100.98%, which raises concerns about confidence in the stock. Given these factors, it may be prudent to hold off on buying until there are clearer signs of recovery or stability in earnings.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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