Seaport Therapeutics Inc

Seaport Therapeutics Inc (SPTX) Stock Analysis

$17.830

+0.234 (+1.31%)At close

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High
18.000
Open
17.630
VWAP
17.66
Volume
184.54K
Mkt Cap
—
Low
17.140
Amount
3.26M
EV/EBITDA, TTM
0.00

Seaport Therapeutics, Inc. is a clinical-stage therapeutics company. The Company is focused on inventing and developing new medicines for patients with depression, anxiety, and other debilitating neuropsychiatric disorders. Its product candidate, GlyphAllo (SPT-300 or Glyph Allopregnanolone), is a novel, Glyphed oral prodrug of allopregnanolone, an endogenous molecule that has been clinically validated in third-party trials for the treatment of postpartum depression. GlyphAgo (SPT-320 or Glyph Agomelatine), is a novel, Glyphed oral prodrug of agomelatine, a clinically validated anxiolytic and antidepressant that is approved for the treatment of generalized anxiety disorder. It is also advancing Glyph2BLS (SPT-348 or Glyph 2-bromo-LSD), a novel, Glyphed oral prodrug of the non-hallucinogenic LSD analog 2-bromo-LSD, in preclinical studies for depressive disorders. GlyphAllo is designed to overcome the bioavailability limitations of allopregnanolone and be durable in MDD.

seaporttx.com

AI analysis of Seaport Therapeutics Inc (SPTX)

Buy

Seaport Therapeutics, Inc. (SPTX) is a good buy right now due to its strong analyst ratings and promising clinical trial results. The stock is currently priced at $17.83, with a forward P/E ratio of 0, indicating no earnings expectations, which can be favorable for growth potential. Analysts have set a price target averaging $37.13, suggesting a substantial upside of 72.61%. The recent positive Phase 1 results for GlyphAllo further enhance its growth prospects, although the company reported a significant net loss of $62.6 million in Q2 2026, which remains a key risk.

Valuation Metrics

The current forward P/E ratio for Seaport Therapeutics Inc (SPTX) is 0.00, compared to its 5-year average forward P/E of .

Forward P/E

5Y Average P/E
Current P/E
0.00

Forward EV/EBITDA

5Y Average EV/EBITDA
Current EV/EBITDA
0.00

Forward P/S

5Y Average P/S
Current P/S
0.00

Whales holding SPTX

S

Sofinnova Investments, Inc.

+ HoldingSPTX

+7.79%

3M Return

G

General Atlantic Service Company, L.P.

+ HoldingSPTX

+2.48%

3M Return

B

Bellevue Asset Management AG

+ HoldingSPTX

-1.47%

3M Return

P

Pentwater Capital Management LP

+ HoldingSPTX

-9.27%

3M Return

A

Artal Group S.A.

+ HoldingSPTX

-20.00%

3M Return

Events Timeline

2026-10-09 (ET)

07:30:00

Seaport Therapeutics Presents Phase 1 Clinical Data for GlyphAgo

2026-10-07 (ET)

07:30:00

Seaport Therapeutics Doses First Patient in GlyphAgo Phase 2a Trial

2026-09-09 (ET)

07:30:00

Seaport Therapeutics Reports Positive Phase 1 Results for GlyphAllo

2026-08-03 (ET)

07:30:00

Seaport Therapeutics Completes IPO and Reports Positive Phase 1 Trial Results for GlyphAgo

2026-05-26 (ET)

11:10:00

SpaceX Files for IPO Aiming to Raise $80 Billion

News

SPTX FAQ — answered by Alphio AI

Seaport Therapeutics, Inc. is a clinical-stage therapeutics company. The Company is focused on inventing and developing new medicines for patients with depression, anxiety, and other debilitating neuropsychiatric disorders. Its product candidate, GlyphAllo (SPT-300 or Glyph Allopregnanolone), is a novel, Glyphed oral prodrug of allopregnanolone, an endogenous molecule that has been clinically validated in third-party trials for the treatment of postpartum depression. GlyphAgo (SPT-320 or Glyph Agomelatine), is a novel, Glyphed oral prodrug of agomelatine, a clinically validated anxiolytic and antidepressant that is approved for the treatment of generalized anxiety disorder. It is also advancing Glyph2BLS (SPT-348 or Glyph 2-bromo-LSD), a novel, Glyphed oral prodrug of the non-hallucinogenic LSD analog 2-bromo-LSD, in preclinical studies for depressive disorders. GlyphAllo is designed to overcome the bioavailability limitations of allopregnanolone and be durable in MDD. It operates in the Healthcare sector.

Seaport Therapeutics, Inc. (SPTX) is a good buy right now due to its strong analyst ratings and promising clinical trial results. The stock is currently priced at $17.83, with a forward P/E ratio of 0, indicating no earnings expectations, which can be favorable for growth potential. Analysts have set a price target averaging $37.13, suggesting a substantial upside of 72.61%. The recent positive Phase 1 results for GlyphAllo further enhance its growth prospects, although the company reported a significant net loss of $62.6 million in Q2 2026, which remains a key risk.

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