Spero Therapeutics Inc (SPRO) FinancialsSPROSpero Therapeutics Inc

Spero Therapeutics, Inc. (SPRO) generates its revenue primarily from Collaboration Revenue Related Party, which accounts for 100.0% of total sales, equivalent to $258.00K. Understanding this concentration is critical for investors evaluating how SPRO navigates market cycles within the Biotechnology & Medical Research industry.

Evaluating the bottom line, Spero Therapeutics, Inc. maintains a gross margin of 100.00%. This metric reflects the company's pricing power and manufacturing efficiency. Further down the income statement, the operating margin stands at -6768.99%, while the net margin is -6494.19%. These profitability ratios, combined with a Return on Equity (ROE) of 19.17%, provide a clear picture of how effectively SPRO converts its operational activities into shareholder value.

In the context of the broader market, SPRO competes directly with industry leaders such as OSTX and NMAD. With a market capitalization of $59.39M, it holds a leading position in the sector. When comparing efficiency, SPRO's gross margin of 100.00% stands against OSTX's N/A and NMAD's N/A. Such benchmarking helps identify whether Spero Therapeutics, Inc. is trading at a premium or discount relative to its financial performance.

Spero's financial performance shows a gross margin consistently at 100%, indicating efficient cost management in its operations. However, it has faced substantial net losses, with a reported loss of $9.6 million in Q2 2026, reflecting ongoing operational challenges.