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SNY Events
Recursion Partners with Sanofi on Development Candidate, Receives $10M Milestone Payment
Recursion (RXRX) announced that Sanofi (SNY) has optioned the first development candidate from the two companies' multi-program research collaboration. The oral small molecule was designed to achieve a differentiated profile against a challenging dual target implicated in inflammatory disease and was delivered by the combination of Recursion's integrated AI-enabled drug design platform and small-molecule chemistry capabilities with Sanofi's deep expertise in drug discovery and immunology. The candidate has now been added to Sanofi's development pipeline and is expected to enter phase 1 clinical trials in 2027, with Sanofi funding and leading further development and commercialization. The option triggered a $10M milestone payment to Recursion, bringing total upfront and milestone payments under the collaboration to $144M to date. Recursion remains eligible for more than $300M in additional milestones under the program, with an average of low double-digit royalties on net product sales if approved. With the first development candidate optioned, the collaboration has now achieved six progress-based milestones across five programs. Additional programs across the collaboration continue to advance. In 2027, other programs in the joint portfolio have the potential to reach development candidate and other progress-based milestones.
Regeneron and Sanofi Expand Antibody Collaboration, Securing $1 Billion Upfront Payment
Regeneron Pharmaceuticals (REGN) and Sanofi (SNY) announced an expansion of their long-standing antibody collaboration, adding multiple next-generation, long-acting antibodies to the alliance that has jointly established Dupixent as the world-leading treatment for diseases driven by type 2 inflammation. The agreement builds on the companies' more than 20-year collaboration, through which more than 1.5M people are currently receiving Dupixent across nine indications, making it one of the most widely used antibody medicines in the world. Under the expanded license and collaboration agreement, the companies will co-develop and co-commercialize four new long-acting, Regeneron-invented antibodies targeting interleukin-13 (IL-13), IL-4xIL-13 bispecific, interleukin-4 and interleukin-4 receptor alpha. IL-13 antibody REGN20423 is currently in a Phase 1 clinical trial for atopic dermatitis, and the other three antibodies are expected to enter clinical studies in 2027. Regeneron will also have the option to include in the collaboration Sanofi's lunsekimig, an investigational bispecific Nanobody VHH therapy targeting TSLP and IL-13, exercisable upon completion of its Phase 3 trials for chronic obstructive pulmonary disease. Under the terms of the agreement, Regeneron will receive an upfront payment of $1B from Sanofi, with the potential for development, regulatory and commercial milestone payments of up to an additional $7B. The companies will share development and commercialization costs for the new programs and will split future profits from these potential products 50:50 on a global basis. Regeneron will lead research and development activities, and Sanofi will lead global commercial efforts. The existing profit-sharing agreement regarding Dupixent will not change.
Trump Announces U.S. Agreement with Greenland for Security Control
Catch up on the top industries and stocks that were impacted, or were predicted to be impacted, by the comments, actions and policies of President Donald Trump with this daily recap compiled by The Fly.GREENLAND DEAL:President Donald Trump said on Friday via Truth Social, "I am pleased to announce that the United States of America has entered into an Agreement with The Kingdom of Denmark, and Greenland, that gives the United States permanent control over security, and all other needs, in Greenland, completely addressing ALL of our many U.S. concerns. There will be NO COST to the United States! At my direction, we worked with representatives of Denmark and Greenland to guarantee that the United States will FOREVER have the complete ability to do what is necessary in Greenland in order to secure and defend the security of Greenland, and the United States of America. Additionally, from now on, no U.S. adversary can EVER have a base in Greenland, have a military presence in Greenland, or make sensitive investments in Greenland, without our express written approval. For over 100 years, Presidents have known the strategic importance of Greenland, but NONE of them were able to do anything about it. I am proud to be the President that permanently and conclusively addressed this very important situation. This is an "Infinite Life" Agreement, there is no end! We are very honored and proud of what has just taken place, and everything agreed to today will be cherished by the American People. We will immediately begin the process of developing a large Military presence in the appropriate part of Greenland, of which there are many. We will work with the people of Greenland in its development and construction. This solution is a great one for the United States of America, Denmark, Greenland, and all of our Allies. We look forward to working with the wonderful people of Denmark and Greenland toward a magnificent future with respect to this large, and highly strategic, parcel of land. We will be very protective of it! This is a dream come true for the United States of America, one that is very important, historic, and special. Thank you for your attention to this matter!"Clear Street expects Critical Metalsshares to be up over 10% this morning due to the Trump administration announcing the U.S. has reached a military security deal with Greenland and Denmark. While additional details have not been released, this is progress in de-escalating the prior rhetoric from the Trump Administration about the U.S. interest in Greenland, the analyst tells investors in a research note. Clear Street says that if a formal agreement is reached, it could help accelerate Critical Metals' investment plan and phases of its Tanbreez project for rare earths mining in Greenland. The firm has a Buy rating on the stock with a $20 price target.AI FORCE:In a post on Truth Social, President Trump stated, "Over the years, there have been many Hoaxes, all generated by the Radical Left Dumocrats, for purposes of destroying our Country. RUSSIA, RUSSIA, RUSSIA, UKRAINE, UKRAINE, UKRAINE, Global Warming, Impeachment Hoax #1, Impeachment Hoax #2, Men in Women's Sports, Transgender for Everyone, and now, the decimation, or destruction, of AI, commonly known as Artificial Intelligence - And I, as President of the United States, will not stand by and let this happen. It all began with an attack on our Data Centers, until people realized how wealthy and prestigious they were for the Communities in which they were built. Higher Salaries, Lower Taxes, and Safer Streets, was the result, and the crazed Data Center attack has largely failed, so now, in much the same way as they changed the term "Global Warming" to "Climate Change," in that it covers a much larger "territory" of doubt, they are going straight at AI. We will not in any way hinder or stifle the Growth of this incredible Industry. Rather, we will cherish it, help it, and watch over it, as it grows! However, we will also be looking for BAD, and we can do that, very easily, with our already existing Criminal and Civil Justice System. For this purpose, I am forming the AI Force, much like I did Space Force, which has been a tremendous SUCCESS, in my First Term. To that end, I will be announcing, in the near future, the AI "Czar" - Only High I.Q. individuals need apply! AI is the next Industrial Revolution, or Internet, but will be even larger and more impactful, possibly as much as 25% of our Country's GDP. We are leading China, and the rest of the World, and I intend to keep it that way! President DONALD J. TRUMP".MEDIA BAN:President Donald Trump stated in a post to Truth Social, "I am proud to announce that, effective immediately, I am banning Fake News CNN, MSNOW (who recently changed their name from MSNBC due to lack of viewership and credibility!), and Politico (The recipients of an illegal and ridiculous $8 Million Dollar subscription, an All Time Record, directly from the United States Government, under Crooked Joe Biden, in order to keep them "alive." Seems like corruption to me!), from the White House as a result of their constant "reporting" FAKE NEWS! Media Outlets shouldn't be able to constantly write or report FICTION and LIES when they're covering the President of the United States, the Trump Administration, or the United States of America. Other Fake News Media Outlets to follow. Thank you for your attention to this matter!"PHARMA DEALS WITH CHINA:The U.S. is working on rules for pharmaceutical companies investing in China that would likely preserve their ability to strike most licensing deals for Chinese drugs, Reuters' Michael Erman, citing three people familiar with the matter. That would mark a departure from the Trump administration's tightening of business with China for other industries under new national security legislation, and would be looser than restrictions sought by some lawmakers, the author notes. Publicly traded companies in the space include AstraZeneca, Bristol Myers, Eli Lilly, GSK, Johnson & Johnson, Merck, Novartis, Pfizer, Rocheand Sanofi.AI REGULATORY PLAN:MetaCEO Mark Zuckerberg, NvidiaCEO Jensen Huang, and Teslaand SpaceX'sElon Musk recently spoke with President Trump and successfully stalled an AI regulatory plan proposed by Demis Hassabis, The Wall Street Journal's Josh Dawsey and Amrith Ramkumar.
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