Replimune Group Inc

Replimune Group Inc (REPL) Stock Analysis

$11.390

-0.678 (-5.95%)At close

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High
12.370
Open
12.050
VWAP
11.71
Volume
1.86M
Mkt Cap
523.26M
Low
11.370
Amount
21.83M
EV/EBITDA, TTM
0.00

Replimune Group, Inc. is a clinical-stage biotechnology company engaged in the development of novel oncolytic immunotherapies. Its proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor-derived antigens and altering of the tumor microenvironment to ignite a systemic response. Its lead product candidate, RP1, is a selectively replicating version of HSV-1 that expresses GALV-GP R(-) and human GM-CSF. Its lead indication for its lead product candidate, RP1, is the potential treatment of advanced melanoma. Its pipeline product candidates include RP2 and RP3. It has designed its RP2 product candidate to express an anti-CTLA-4 antibody-like protein intended to block the inhibition of the immune response.

AI analysis of Replimune Group Inc (REPL)

Buy

Replimune Group Inc is a good buy right now due to its current price of $13.42, which is significantly below the analyst price targets of $20 to $21, indicating a potential upside of 48% to 56%. Additionally, the stock has shown strong momentum with a year-to-date change of +50.79% and a one-year change of +194.30%, suggesting robust investor interest and market confidence. However, the company is facing a risk with a negative net income of -69,730,000 USD for Q1 2027, which highlights ongoing financial challenges.

Analyst Ratings (3)

+0.35% upside
Buy
3 Buy
0 Hold
0 Sell
Current: 11.39
Low
3.00
Average
11.43
High
18.00

JPMorgan

2026-08-26

Price Target

$21

Overweight

BMO Capital

2026-08-07

Price Target

$20

Outperform

Wedbush

2026-08-07

Price Target

$19

Outperform

Leerink

2026-08-04

Price Target

$17

Outperform

Wedbush

2026-07-31

Price Target

$12

Neutral

Valuation Metrics

The current forward P/E ratio for Replimune Group Inc (REPL) is 0.00, compared to its 5-year average forward P/E of -5.04.

Forward P/E

Overvalued
5Y Average P/E
-5.04
Current P/E
0.00
Overvalued
-2.42
Undervalued
-7.66

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-1.50
Current EV/EBITDA
0.00
Overvalued
0.62
Undervalued
-3.62

Forward P/S

Fair
5Y Average P/S
13.37
Current P/S
6.61
Overvalued
45.70
Undervalued
-18.96

Whales holding REPL

C

Caption Management, LLC

+ HoldingREPL

+2.69%

3M Return

S

Suvretta Capital Management, LLC

+ HoldingREPL

-11.47%

3M Return

R

RTW Investments, LP

+ HoldingREPL

-11.48%

3M Return

Events Timeline

2026-10-10 (ET)

16:00:00

MiniMed Short Interest Rises to 102.9%

2026-10-01 (ET)

16:30:00

Replimune Announces Tudriqev Now Available in the U.S.

2026-08-14 (ET)

17:00:00

Replimune Files Automatic Mixed Securities Shelf

2026-08-10 (ET)

08:30:00

Leerink, JPMorgan and Cantor Fitzgerald Jointly Manage Offering

2026-08-06 (ET)

18:00:00

Replimune Receives FDA Accelerated Approval for Tudriqev in Melanoma

News

REPL FAQ — answered by Alphio AI

Replimune Group, Inc. is a clinical-stage biotechnology company engaged in the development of novel oncolytic immunotherapies. Its proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor-derived antigens and altering of the tumor microenvironment to ignite a systemic response. Its lead product candidate, RP1, is a selectively replicating version of HSV-1 that expresses GALV-GP R(-) and human GM-CSF. Its lead indication for its lead product candidate, RP1, is the potential treatment of advanced melanoma. Its pipeline product candidates include RP2 and RP3. It has designed its RP2 product candidate to express an anti-CTLA-4 antibody-like protein intended to block the inhibition of the immune response. It operates in the Healthcare sector (BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES) industry).

Replimune Group Inc is a good buy right now due to its current price of $13.42, which is significantly below the analyst price targets of $20 to $21, indicating a potential upside of 48% to 56%. Additionally, the stock has shown strong momentum with a year-to-date change of +50.79% and a one-year change of +194.30%, suggesting robust investor interest and market confidence. However, the company is facing a risk with a negative net income of -69,730,000 USD for Q1 2027, which highlights ongoing financial challenges.

3 analysts cover REPL: 3 rate it Buy, 0 Hold and 0 Sell. The average price target is 11.43.

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