Personalis Inc

Personalis Inc (PSNL) Stock Analysis

$15.930

+0.030 (+0.19%)At close

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High
16.080
Open
15.880
VWAP
15.95
Volume
2.14M
Mkt Cap
62.85M
Low
15.830
Amount
34.14M
EV/EBITDA, TTM
-10.54

Personalis, Inc. is engaged in developing, marketing and selling advanced cancer genomic tests and analytics. The Company’s advanced genomic sequencing and analytics support the development of personalized cancer vaccines and other cancer immunotherapies. Its products include NeXT Personal, ImmunoI DNeXT, NeXT Personal Dx, NeXT Dx, whole exome sequencing (WES), and whole genome sequencing (WGS). NeXT Personal is a tumor-informed liquid biopsy test for the detection of minimal residual disease (MRD) and recurrence in cancer. NeXT Dx is a comprehensive tumor profiling test that is used to help select therapy for a cancer patient and identify potential clinical trials for a patient. The Company performed WGS on human samples for research projects, such as population sequencing initiatives. The Company’s tests and analytics are used by pharmaceutical companies for translational research, biomarker discovery, and the development of personalized cancer therapies.

AI analysis of Personalis Inc (PSNL)

Hold

Currently, Personalis Inc (PSNL) is trading at $16, which is close to the analyst price target of $16.25 set by BTIG. The stock has shown a significant year-to-date increase of 103.82%, indicating strong performance over the past year. However, the RSI is at 34.913, suggesting that the stock is nearing oversold territory, which could indicate a potential rebound. The main risk is the negative net income reported, which reached -$31,683,000 in Q2 2026, reflecting ongoing financial challenges. Given these factors, it may be prudent to hold rather than buy at this time, as the stock is currently at a high valuation with uncertain profitability prospects.

Valuation Metrics

The current forward P/E ratio for Personalis Inc (PSNL) is 0.00, compared to its 5-year average forward P/E of -3.00.

Forward P/E

Overvalued
5Y Average P/E
-3.00
Current P/E
0.00
Overvalued
-0.62
Undervalued
-5.39

Forward EV/EBITDA

Strongly Undervalued
5Y Average EV/EBITDA
-2.58
Current EV/EBITDA
-10.54
Overvalued
0.48
Undervalued
-5.64

Forward P/S

Strongly Overvalued
5Y Average P/S
4.82
Current P/S
15.41
Overvalued
8.81
Undervalued
0.84

Alphio AI Price Scenarios for PSNL

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%PSNL

$5.07

Scenario price

B

Base

Base · 50%PSNL

$4.87

Scenario price

B

Bear

Bear · 25%PSNL

$4.83

Scenario price

Whales holding PSNL

L

Lightspeed Ventures, LLC

+ HoldingPSNL

+30.07%

3M Return

Events Timeline

2026-08-24 (ET)

09:00:00

Craig-Hallum Downgrades Personalis to Hold with $16.25 Price Target

2026-07-20 (ET)

16:30:00

Nasdaq Closes Near Flat as Market Eyes Megacap Earnings

15:00:00

Morgan Stanley: Tempus AI Acquires Personalis for $16.25 per Share

14:30:00

Tempus AI Acquires Personalis at $16.25 per Share

12:30:00

Tech Stocks Rebound as Market Eyes Megacap Earnings

News

PSNL FAQ — answered by Alphio AI

Personalis, Inc. is engaged in developing, marketing and selling advanced cancer genomic tests and analytics. The Company’s advanced genomic sequencing and analytics support the development of personalized cancer vaccines and other cancer immunotherapies. Its products include NeXT Personal, ImmunoI DNeXT, NeXT Personal Dx, NeXT Dx, whole exome sequencing (WES), and whole genome sequencing (WGS). NeXT Personal is a tumor-informed liquid biopsy test for the detection of minimal residual disease (MRD) and recurrence in cancer. NeXT Dx is a comprehensive tumor profiling test that is used to help select therapy for a cancer patient and identify potential clinical trials for a patient. The Company performed WGS on human samples for research projects, such as population sequencing initiatives. The Company’s tests and analytics are used by pharmaceutical companies for translational research, biomarker discovery, and the development of personalized cancer therapies. It operates in the Healthcare sector (SERVICES-MEDICAL LABORATORIES industry).

Currently, Personalis Inc (PSNL) is trading at $16, which is close to the analyst price target of $16.25 set by BTIG. The stock has shown a significant year-to-date increase of 103.82%, indicating strong performance over the past year. However, the RSI is at 34.913, suggesting that the stock is nearing oversold territory, which could indicate a potential rebound. The main risk is the negative net income reported, which reached -$31,683,000 in Q2 2026, reflecting ongoing financial challenges. Given these factors, it may be prudent to hold rather than buy at this time, as the stock is currently at a high valuation with uncertain profitability prospects.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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