Bull
$4.01
Scenario price
$9.830
-0.645 (-6.56%)At close
Puma Biotechnology, Inc. is a biopharmaceutical company with a focus on the development and commercialization of products to enhance cancer care. The Company is commercializing NERLYNX, an oral version of neratinib, for the treatment of certain HER2-positive breast cancers. NERLYNX is approved in the United States for two indications: the extended adjuvant treatment of adult patients with early stage HER2-overexpressed/amplified breast cancer following adjuvant trastuzumab-based therapy and for use in combination with capecitabine for the treatment of adult patients with advanced or metastatic HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens in the metastatic setting. The Company is focused on the global development and commercialization of alisertib. Alisertib is a selective, small-molecule inhibitor of Aurora Kinase A that is designed to disrupt mitosis, leading to apoptosis of rapidly proliferating tumor cells.
Puma Biotechnology Inc is currently trading at $9.83, which is above the analyst price target of $6, indicating that it may not be an attractive buy at this moment. The stock has a forward P/E ratio of 3.46, suggesting it is undervalued, but the RSI is at 42.73, indicating it is nearing oversold territory. The recent insider selling has increased by 230.93%, which raises concerns about future performance. Therefore, while the fundamentals show potential with a gross margin of 77.92%, the current market sentiment and insider activity suggest holding off on new purchases for now.
TD Cowen
$6
2026-08-07
TD Cowen
2026-08-07
Price Target
$6
HC Wainwright & Co.
$7
2025-02-28
HC Wainwright & Co.
2025-02-28
Price Target
$7
HC Wainwright & Co.
$7
2024-12-23
HC Wainwright & Co.
2024-12-23
Price Target
$7
HC Wainwright & Co.
$7
2024-11-20
HC Wainwright & Co.
2024-11-20
Price Target
$7
HC Wainwright & Co.
$7
2024-11-08
HC Wainwright & Co.
2024-11-08
Price Target
$7
Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

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Puma Biotechnology, Inc. is a biopharmaceutical company with a focus on the development and commercialization of products to enhance cancer care. The Company is commercializing NERLYNX, an oral version of neratinib, for the treatment of certain HER2-positive breast cancers. NERLYNX is approved in the United States for two indications: the extended adjuvant treatment of adult patients with early stage HER2-overexpressed/amplified breast cancer following adjuvant trastuzumab-based therapy and for use in combination with capecitabine for the treatment of adult patients with advanced or metastatic HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens in the metastatic setting. The Company is focused on the global development and commercialization of alisertib. Alisertib is a selective, small-molecule inhibitor of Aurora Kinase A that is designed to disrupt mitosis, leading to apoptosis of rapidly proliferating tumor cells. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).
Puma Biotechnology Inc is currently trading at $9.83, which is above the analyst price target of $6, indicating that it may not be an attractive buy at this moment. The stock has a forward P/E ratio of 3.46, suggesting it is undervalued, but the RSI is at 42.73, indicating it is nearing oversold territory. The recent insider selling has increased by 230.93%, which raises concerns about future performance. Therefore, while the fundamentals show potential with a gross margin of 77.92%, the current market sentiment and insider activity suggest holding off on new purchases for now.
9 analysts cover PBYI: 8 rate it Buy, 1 Hold and 0 Sell. The average price target is 3.50.
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