Parabilis Medicines Inc

Parabilis Medicines Inc (PBLS) Stock Analysis

$25.180

-0.690 (-2.74%)At close

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High
26.435
Open
25.760
VWAP
25.47
Volume
955.21K
Mkt Cap
—
Low
24.800
Amount
24.33M
EV/EBITDA, TTM
-1.99

Parabilis Medicines, Inc., formerly FOG Pharmaceuticals, Inc., is a clinical-stage biopharmaceutical company. It is built to develop transformative medicines addressing undruggable protein targets driving human disease. It leverages a proprietary platform to a novel therapeutic modality, Helicons, which are stabilized helical peptides engineered to bind and precisely modulate proteins that reach conventional medicine. Its lead product candidate, zolucatetide, is the first and only investigational therapy that inhibits the b-catenin: TCF interaction, the critical downstream node of the Wnt/b-catenin pathway. Its preclinical pipeline provides the Helicon approach and includes programs targeting two drivers of prostate cancer, the ETS-related gene and the androgen receptor (AR) in its active state (ARON). The Helicon discovery platform integrates advanced AI and physics-based computational modeling with peptide synthesis and experimental screening to discover and develop drug candidates.

AI analysis of Parabilis Medicines Inc (PBLS)

Hold

Currently, Parabilis Medicines Inc (PBLS) is not a strong buy due to its low RSI of 16.87, indicating it is oversold, and a significant recent decline of 25.49% over the last 20 days. However, analysts project a price target of $40-$45, which suggests potential upside from the current price of $27.48. The main risk is the company's negative earnings trend, with a reported EPS of -2.13, which raises concerns about profitability.

Valuation Metrics

The current forward P/E ratio for Parabilis Medicines Inc (PBLS) is 0.00, compared to its 5-year average forward P/E of .

Forward P/E

5Y Average P/E
Current P/E
0.00

Forward EV/EBITDA

Strongly Overvalued
5Y Average EV/EBITDA
-2.98
Current EV/EBITDA
-1.99
Overvalued
-2.51
Undervalued
-3.45

Forward P/S

Strongly Undervalued
5Y Average P/S
1334.54
Current P/S
995.06
Overvalued
1494.94
Undervalued
1174.15

Whales holding PBLS

I

ICONIQ Capital, LLC

+ HoldingPBLS

+23.23%

3M Return

D

Deerfield Management Company, L.P.

+ HoldingPBLS

-6.90%

3M Return

R

Rock Springs Capital Management LP

+ HoldingPBLS

-9.08%

3M Return

F

Frazier Life Sciences Management, LP

+ HoldingPBLS

-21.51%

3M Return

R

RA Capital Management, L.P.

+ HoldingPBLS

-23.27%

3M Return

V

VR Management, LLC

+ HoldingPBLS

-33.04%

3M Return

Events Timeline

2026-10-12 (ET)

12:30:00

Parabilis Medicines Stock Rises 6.3% to $29.20

2026-09-21 (ET)

12:30:00

Parabilis Medicines Shares Drop 12.5% to $36.51

2026-08-25 (ET)

09:30:00

Parabilis Medicines Appoints Craig Tendler to Board of Directors

2026-08-13 (ET)

07:30:00

Parabilis Medicines Q2 Revenue $148K, Misses Consensus $16.67M

News

PBLS FAQ — answered by Alphio AI

Parabilis Medicines, Inc., formerly FOG Pharmaceuticals, Inc., is a clinical-stage biopharmaceutical company. It is built to develop transformative medicines addressing undruggable protein targets driving human disease. It leverages a proprietary platform to a novel therapeutic modality, Helicons, which are stabilized helical peptides engineered to bind and precisely modulate proteins that reach conventional medicine. Its lead product candidate, zolucatetide, is the first and only investigational therapy that inhibits the b-catenin: TCF interaction, the critical downstream node of the Wnt/b-catenin pathway. Its preclinical pipeline provides the Helicon approach and includes programs targeting two drivers of prostate cancer, the ETS-related gene and the androgen receptor (AR) in its active state (ARON). The Helicon discovery platform integrates advanced AI and physics-based computational modeling with peptide synthesis and experimental screening to discover and develop drug candidates. It operates in the Healthcare sector.

Currently, Parabilis Medicines Inc (PBLS) is not a strong buy due to its low RSI of 16.87, indicating it is oversold, and a significant recent decline of 25.49% over the last 20 days. However, analysts project a price target of $40-$45, which suggests potential upside from the current price of $27.48. The main risk is the company's negative earnings trend, with a reported EPS of -2.13, which raises concerns about profitability.

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