Palisade Bio Inc

Palisade Bio Inc (PALI) Stock Analysis

$1.190

-0.010 (-0.83%)At close

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High
1.220
Open
1.220
VWAP
1.17
Volume
15.12M
Mkt Cap
4.28M
Low
1.100
Amount
17.69M
EV/EBITDA, TTM
0.00

Palisade Bio, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing and advancing therapeutics for patients living with autoimmune, inflammatory, and fibrotic diseases. The Company’s lead product candidate, PALI-2108, is being developed as a treatment for patients living with inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Fibrostenotic Crohn’s disease (FSCD). The Company is conducting a Phase I human clinical trial of its lead product candidate, PALI-2108, for the treatment of UC. In UC mouse models, the Company has demonstrated the dose-dependent efficacy of PALI-2108. It utilizes dextran sodium sulfate (DSS)-induced UC mouse models and targets engagement in oxazolone-induced colitis. PALI-2108 targets the key phosphodiesterase-4 (PDE4) in colon tissues and prevents it from breaking down cyclic Adenosine Monophosphate (cAMP) molecules which regulate inflammation in the body.

AI analysis of Palisade Bio Inc (PALI)

Hold

Palisade Bio Inc (PALI) is currently not a strong buy due to its low current price of $1.33 and a concerning RSI of 34.158, indicating potential oversold conditions. While the company has received FDA clearance for its Crohn's disease clinical trial, which could drive future growth, it reported a significant net loss of $10.6 million in Q2 2026, raising concerns about its financial health. The stock has also seen a year-to-date decline of 46.80%, reflecting market skepticism. However, the analyst price targets suggest a potential upside of 350% to 500%, which could be attractive for long-term investors willing to accept the risks involved.

Valuation Metrics

The current forward P/E ratio for Palisade Bio Inc (PALI) is 0.00, compared to its 5-year average forward P/E of -1.36.

Forward P/E

Fair
5Y Average P/E
-1.36
Current P/E
0.00
Overvalued
0.58
Undervalued
-3.31

Forward EV/EBITDA

Strongly Undervalued
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued
0.00
Undervalued
0.00

Forward P/S

Fair
5Y Average P/S
9.53
Current P/S
0.00
Overvalued
32.48
Undervalued
-13.42

Alphio AI Price Scenarios for PALI

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%PALI

$0.77

Scenario price

B

Base

Base · 50%PALI

$0.74

Scenario price

B

Bear

Bear · 25%PALI

$0.61

Scenario price

Whales holding PALI

S

Soleus Capital Management, L.P.

+ HoldingPALI

-3.44%

3M Return

Events Timeline

2026-10-28 (ET)

09:58:00

Palisade Bio Doses First Patient in ASCENTRA-UC Trial

2026-10-20 (ET)

08:30:00

Palisade Bio Presents PALI-2108 Clinical Findings at UEG Week

2026-09-23 (ET)

09:00:00

Palisade Bio Receives Health Canada Approval for Ascentra-UC Clinical Trial

2026-09-22 (ET)

09:00:00

Palisade Bio Receives FDA Clearance for PALI-2108 to Initiate Phase 2 Trial

2026-08-10 (ET)

17:30:00

Perspective CEO Highlights Clinical Progress and Manufacturing Facility Development

News

PALI FAQ — answered by Alphio AI

Palisade Bio, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing and advancing therapeutics for patients living with autoimmune, inflammatory, and fibrotic diseases. The Company’s lead product candidate, PALI-2108, is being developed as a treatment for patients living with inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Fibrostenotic Crohn’s disease (FSCD). The Company is conducting a Phase I human clinical trial of its lead product candidate, PALI-2108, for the treatment of UC. In UC mouse models, the Company has demonstrated the dose-dependent efficacy of PALI-2108. It utilizes dextran sodium sulfate (DSS)-induced UC mouse models and targets engagement in oxazolone-induced colitis. PALI-2108 targets the key phosphodiesterase-4 (PDE4) in colon tissues and prevents it from breaking down cyclic Adenosine Monophosphate (cAMP) molecules which regulate inflammation in the body. It operates in the Healthcare sector (BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES) industry).

Palisade Bio Inc (PALI) is currently not a strong buy due to its low current price of $1.33 and a concerning RSI of 34.158, indicating potential oversold conditions. While the company has received FDA clearance for its Crohn's disease clinical trial, which could drive future growth, it reported a significant net loss of $10.6 million in Q2 2026, raising concerns about its financial health. The stock has also seen a year-to-date decline of 46.80%, reflecting market skepticism. However, the analyst price targets suggest a potential upside of 350% to 500%, which could be attractive for long-term investors willing to accept the risks involved.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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