Omeros Corp

Omeros Corp (OMER) Stock Analysis

$16.350

+0.152 (+0.93%)At close

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High
16.650
Open
16.280
VWAP
16.35
Volume
1.38M
Mkt Cap
228.88M
Low
16.045
Amount
22.61M
EV/EBITDA, TTM
846.21

Omeros Corporation is a clinical-stage biopharmaceutical company. The Company focuses on discovering, developing, and commercializing first-in-class small-molecule and protein therapeutics for both large-market and orphan indications, with a particular emphasis on complement-mediated diseases, cancers, and addictive or compulsive disorders. Its clinical-stage development programs include: narsoplimab, its antibody targeting mannan-binding lectin-associated serine protease 2 (MASP-2), the effector enzyme of the lectin pathway of complement; OMS1029, its long-acting antibody targeting MASP-2; and OMS527, its phosphodiesterase 7 (PDE7) inhibitor program. Its commercial product, YARTEMLEA, is the approved inhibitor of the lectin pathway of complement. YARTEMLEA is used for the treatment of TA-TMA in adults and in children ages two years and older. YARTEMLEA selectively inhibits MASP-2, blocking pathway activation while preserving classical and alternative complement pathway functions.

AI analysis of Omeros Corp (OMER)

Buy

Omeros Corp is a good buy right now due to its current price of $16.2, which is significantly below the analyst price target of $22, suggesting a potential upside of 35%. Additionally, the gross margin has improved to 97.20% in Q2 2026, indicating strong profitability potential. However, the main risk is the negative opinion from the European Medicines Agency, which could impact future revenue streams.

Analyst Ratings (7)

+167.09% upside
Buy
6 Buy
1 Hold
0 Sell
Current: 16.35
Low
36.00
Average
43.67
High
55.00

Cantor Fitzgerald

2026-09-22

Price Target

$22

Overweight

H.C. Wainwright

2026-07-27

Price Target

$10.84

Buy

H.C. Wainwright

2026-06-26

Price Target

$33

Buy

H.C. Wainwright

2025-12-24

Price Target

$20

Buy

H.C. Wainwright

2025-06-27

Price Target

$9

Buy

Valuation Metrics

The current forward P/E ratio for Omeros Corp (OMER) is 87.72, compared to its 5-year average forward P/E of 2.63.

Forward P/E

Strongly Overvalued
5Y Average P/E
2.63
Current P/E
87.72
Overvalued
23.17
Undervalued
-17.90

Forward EV/EBITDA

Strongly Overvalued
5Y Average EV/EBITDA
-50.91
Current EV/EBITDA
846.21
Overvalued
274.68
Undervalued
-376.51

Forward P/S

Fair
5Y Average P/S
25.83
Current P/S
5.30
Overvalued
59.65
Undervalued
-7.99

Alphio AI Price Scenarios for OMER

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%OMER

$3.00

Scenario price

B

Base

Base · 50%OMER

$3.00

Scenario price

B

Bear

Bear · 25%OMER

$2.71

Scenario price

Whales holding OMER

I

Ingalls & Snyder, LLC

+ HoldingOMER

+10.27%

3M Return

Events Timeline

2026-10-16 (ET)

17:00:00

Nasdaq Falls 2% Amid AI Investment Concerns

12:00:00

Dow Rises Slightly, Nasdaq Falls 1%

06:30:00

Omeros Faces Rejection for YARTEMLEA Marketing Authorization

2026-08-13 (ET)

16:30:00

Major Averages Rise as Oil Prices Fall

12:00:00

Major Averages Rise as Oil Prices Fall

News

OMER FAQ — answered by Alphio AI

Omeros Corporation is a clinical-stage biopharmaceutical company. The Company focuses on discovering, developing, and commercializing first-in-class small-molecule and protein therapeutics for both large-market and orphan indications, with a particular emphasis on complement-mediated diseases, cancers, and addictive or compulsive disorders. Its clinical-stage development programs include: narsoplimab, its antibody targeting mannan-binding lectin-associated serine protease 2 (MASP-2), the effector enzyme of the lectin pathway of complement; OMS1029, its long-acting antibody targeting MASP-2; and OMS527, its phosphodiesterase 7 (PDE7) inhibitor program. Its commercial product, YARTEMLEA, is the approved inhibitor of the lectin pathway of complement. YARTEMLEA is used for the treatment of TA-TMA in adults and in children ages two years and older. YARTEMLEA selectively inhibits MASP-2, blocking pathway activation while preserving classical and alternative complement pathway functions. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Omeros Corp is a good buy right now due to its current price of $16.2, which is significantly below the analyst price target of $22, suggesting a potential upside of 35%. Additionally, the gross margin has improved to 97.20% in Q2 2026, indicating strong profitability potential. However, the main risk is the negative opinion from the European Medicines Agency, which could impact future revenue streams.

7 analysts cover OMER: 6 rate it Buy, 1 Hold and 0 Sell. The average price target is 43.67.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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