Omeros Corp

Omeros Corp (OMER) Stock Analysis

$16.570

-0.285 (-1.72%)At close

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High
16.800
Open
16.800
VWAP
16.58
Volume
699.39K
Mkt Cap
228.88M
Low
16.370
Amount
11.60M
EV/EBITDA, TTM
878.44

Omeros Corporation is a clinical-stage biopharmaceutical company. The Company focuses on discovering, developing, and commercializing first-in-class small-molecule and protein therapeutics for both large-market and orphan indications, with a particular emphasis on complement-mediated diseases, cancers, and addictive or compulsive disorders. Its clinical-stage development programs include: narsoplimab, its antibody targeting mannan-binding lectin-associated serine protease 2 (MASP-2), the effector enzyme of the lectin pathway of complement; OMS1029, its long-acting antibody targeting MASP-2; and OMS527, its phosphodiesterase 7 (PDE7) inhibitor program. Its commercial product, YARTEMLEA, is the approved inhibitor of the lectin pathway of complement. YARTEMLEA is used for the treatment of TA-TMA in adults and in children ages two years and older. YARTEMLEA selectively inhibits MASP-2, blocking pathway activation while preserving classical and alternative complement pathway functions.

AI analysis of Omeros Corp (OMER)

Buy

Omeros Corp is a good buy right now due to its current price of $16.57, which is significantly below the analyst price target of $33, indicating a potential upside of about 99%. Additionally, the company has shown strong gross margins of 97.20% in Q2 2026, reflecting efficient operations despite recent challenges. The main risk is the recent EMA rejection of its drug, which could affect future revenue streams, but analysts believe this selloff is overdone, providing a favorable entry point.

Analyst Ratings (7)

+163.55% upside
Buy
6 Buy
1 Hold
0 Sell
Current: 16.57
Low
36.00
Average
43.67
High
55.00

Cantor Fitzgerald

2026-09-22

Price Target

$22

Overweight

H.C. Wainwright

2026-07-27

Price Target

$10.84

Buy

H.C. Wainwright

2026-06-26

Price Target

$33

Buy

H.C. Wainwright

2025-12-24

Price Target

$20

Buy

H.C. Wainwright

2025-06-27

Price Target

$9

Buy

Valuation Metrics

The current forward P/E ratio for Omeros Corp (OMER) is 87.72, compared to its 5-year average forward P/E of 2.92.

Forward P/E

Strongly Overvalued
5Y Average P/E
2.92
Current P/E
87.72
Overvalued
24.01
Undervalued
-18.16

Forward EV/EBITDA

Strongly Overvalued
5Y Average EV/EBITDA
-48.08
Current EV/EBITDA
878.44
Overvalued
281.55
Undervalued
-377.71

Forward P/S

Fair
5Y Average P/S
25.82
Current P/S
5.51
Overvalued
59.63
Undervalued
-8.00

Alphio AI Price Scenarios for OMER

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%OMER

$3.00

Scenario price

B

Base

Base · 50%OMER

$3.00

Scenario price

B

Bear

Bear · 25%OMER

$2.71

Scenario price

Whales holding OMER

I

Ingalls & Snyder, LLC

+ HoldingOMER

+0.13%

3M Return

Events Timeline

2026-10-16 (ET)

17:00:00

Nasdaq Falls 2% Amid AI Investment Concerns

12:00:00

Dow Rises Slightly, Nasdaq Falls 1%

06:30:00

Omeros Faces Rejection for YARTEMLEA Marketing Authorization

2026-08-13 (ET)

16:30:00

Major Averages Rise as Oil Prices Fall

12:00:00

Major Averages Rise as Oil Prices Fall

News

OMER FAQ — answered by Alphio AI

Omeros Corporation is a clinical-stage biopharmaceutical company. The Company focuses on discovering, developing, and commercializing first-in-class small-molecule and protein therapeutics for both large-market and orphan indications, with a particular emphasis on complement-mediated diseases, cancers, and addictive or compulsive disorders. Its clinical-stage development programs include: narsoplimab, its antibody targeting mannan-binding lectin-associated serine protease 2 (MASP-2), the effector enzyme of the lectin pathway of complement; OMS1029, its long-acting antibody targeting MASP-2; and OMS527, its phosphodiesterase 7 (PDE7) inhibitor program. Its commercial product, YARTEMLEA, is the approved inhibitor of the lectin pathway of complement. YARTEMLEA is used for the treatment of TA-TMA in adults and in children ages two years and older. YARTEMLEA selectively inhibits MASP-2, blocking pathway activation while preserving classical and alternative complement pathway functions. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Omeros Corp is a good buy right now due to its current price of $16.57, which is significantly below the analyst price target of $33, indicating a potential upside of about 99%. Additionally, the company has shown strong gross margins of 97.20% in Q2 2026, reflecting efficient operations despite recent challenges. The main risk is the recent EMA rejection of its drug, which could affect future revenue streams, but analysts believe this selloff is overdone, providing a favorable entry point.

7 analysts cover OMER: 6 rate it Buy, 1 Hold and 0 Sell. The average price target is 43.67.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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