Olema Pharmaceuticals Inc

Olema Pharmaceuticals Inc (OLMA) Stock Analysis

$10.270

-0.495 (-4.82%)At close

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High
10.770
Open
10.690
VWAP
10.41
Vol
740.85K
Mkt Cap
627.02M
Low
10.190
Amount
7.71M
EV/EBITDA, TTM
0.00

Olema Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It is advancing a pipeline of novel therapies by leveraging its deep understanding of endocrine-driven cancers, nuclear receptors, and mechanisms of acquired resistance. Its lead product candidate, palazestrant (OP-1250), is a novel, orally available small molecule with dual activity as both a complete estrogen receptor (ER) antagonist (CERAN) and selective ER degrader (SERD). It is being investigated in patients with recurrent, locally advanced or metastatic ER-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer. Its second product candidate in clinical development, called OP-3136, is a novel, orally available small molecule that potently and selectively inhibits KAT6, an epigenetic target that is dysregulated in breast and other cancers.

olema.com

AI analysis of Olema Pharmaceuticals Inc (OLMA)

hold

Olema Pharmaceuticals is not a good buy right now due to its current price of $10.27, which is significantly lower than the average analyst price target of $46, indicating potential upside. However, the stock has a low RSI of 33.33, suggesting it is oversold, but the negative trend and increasing losses pose a risk. The main risk is the projected EPS for Q2 2026 of -0.61, which was worse than the estimate of -0.53, indicating ongoing financial struggles.

Valuation Metrics

The current forward P/E ratio for Olema Pharmaceuticals Inc (OLMA) is 0.00, compared to its 5-year average forward P/E of -4.46.

Forward P/E

Overvalued
5Y Average P/E
-4.46
Current P/E
0.00
Overvalued
-1.03
Undervalued
-7.90

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-1.58
Current EV/EBITDA
0.00
Overvalued
1.02
Undervalued
-4.19

Forward P/S

Fair
5Y Average P/S
49.06
Current P/S
148.87
Overvalued
256.74
Undervalued
-158.63

Alphio AI Price Scenarios for OLMA

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%OLMA

$5.67

Scenario price

B

Base

Base · 50%OLMA

$4.93

Scenario price

B

Bear

Bear · 25%OLMA

$4.65

Scenario price

Whales holding OLMA

L

Lightspeed Ventures, LLC

+ HoldingOLMA

+19.46%

3M Return

L

Logos Global Management, L.P.

+ HoldingOLMA

+17.53%

3M Return

B

Bain Capital Life Sciences Investors, LLC

+ HoldingOLMA

+14.97%

3M Return

B

BVF Partners L.P.

+ HoldingOLMA

+11.78%

3M Return

R

Readystate Asset Management LP

+ HoldingOLMA

+11.43%

3M Return

A

Artal Group S.A.

+ HoldingOLMA

-0.61%

3M Return

Events Timeline

2026-08-13 (ET)

09:30:00

Olema Appoints Jason O'Byrne as CFO

2026-08-10 (ET)

16:30:00

Olema Oncology Completes OPERA-01 Trial Enrollment, Expects Data in Q1 2027

2026-05-26 (ET)

07:10:00

Olema Pharmaceuticals Announces Clinical Trial Collaboration with Bayer

2026-05-12 (ET)

07:20:00

Olema Oncology Anticipates OPERA-01 Trial Data Release

2026-03-16 (ET)

07:10:00

Olema Oncology Raises $218.5 Million in Public Offering

News

OLMA FAQ — answered by Alphio AI

Olema Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It is advancing a pipeline of novel therapies by leveraging its deep understanding of endocrine-driven cancers, nuclear receptors, and mechanisms of acquired resistance. Its lead product candidate, palazestrant (OP-1250), is a novel, orally available small molecule with dual activity as both a complete estrogen receptor (ER) antagonist (CERAN) and selective ER degrader (SERD). It is being investigated in patients with recurrent, locally advanced or metastatic ER-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer. Its second product candidate in clinical development, called OP-3136, is a novel, orally available small molecule that potently and selectively inhibits KAT6, an epigenetic target that is dysregulated in breast and other cancers. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Olema Pharmaceuticals is not a good buy right now due to its current price of $10.27, which is significantly lower than the average analyst price target of $46, indicating potential upside. However, the stock has a low RSI of 33.33, suggesting it is oversold, but the negative trend and increasing losses pose a risk. The main risk is the projected EPS for Q2 2026 of -0.61, which was worse than the estimate of -0.53, indicating ongoing financial struggles.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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