Olema Pharmaceuticals Inc

Olema Pharmaceuticals Inc (OLMA) Stock Analysis

$6.870

+0.071 (+1.03%)At close

Loading chart…
High
6.945
Open
6.840
VWAP
6.84
Volume
1.09M
Mkt Cap
627.02M
Low
6.700
Amount
7.44M
EV/EBITDA, TTM
0.00

Olema Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It is advancing a pipeline of novel therapies by leveraging its deep understanding of endocrine-driven cancers, nuclear receptors, and mechanisms of acquired resistance. Its lead product candidate, palazestrant (OP-1250), is a novel, orally available small molecule with dual activity as both a complete estrogen receptor (ER) antagonist (CERAN) and selective ER degrader (SERD). It is being investigated in patients with recurrent, locally advanced or metastatic ER-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer. Its second product candidate in clinical development, called OP-3136, is a novel, orally available small molecule that potently and selectively inhibits KAT6, an epigenetic target that is dysregulated in breast and other cancers.

olema.com

AI analysis of Olema Pharmaceuticals Inc (OLMA)

Sell

Currently, Olema Pharmaceuticals Inc (OLMA) is not a good buy. The stock is trading at $7.82, significantly below its analyst price targets, which range from $20 to $59. However, the stock has a very low RSI of 14.106, indicating it is oversold, but the overall trend is negative with a year-to-date change of -69.07%. The main risk is its ongoing losses, with a net income of -$63.2 million reported for Q2 2026, which raises concerns about its financial sustainability.

Valuation Metrics

The current forward P/E ratio for Olema Pharmaceuticals Inc (OLMA) is 0.00, compared to its 5-year average forward P/E of -4.19.

Forward P/E

Overvalued
5Y Average P/E
-4.19
Current P/E
0.00
Overvalued
-1.09
Undervalued
-7.30

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-1.40
Current EV/EBITDA
0.00
Overvalued
1.01
Undervalued
-3.81

Forward P/S

Fair
5Y Average P/S
52.40
Current P/S
96.85
Overvalued
260.33
Undervalued
-155.53

Alphio AI Price Scenarios for OLMA

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%OLMA

$5.67

Scenario price

B

Base

Base · 50%OLMA

$4.93

Scenario price

B

Bear

Bear · 25%OLMA

$4.65

Scenario price

Whales holding OLMA

L

Lightspeed Ventures, LLC

+ HoldingOLMA

+30.07%

3M Return

P

Paradigm Biocapital Advisors LP

+ HoldingOLMA

-0.49%

3M Return

Events Timeline

2026-08-13 (ET)

09:30:00

Olema Appoints Jason O'Byrne as CFO

2026-08-10 (ET)

16:30:00

Olema Oncology Completes OPERA-01 Trial Enrollment, Expects Data in Q1 2027

2026-05-26 (ET)

07:10:00

Olema Pharmaceuticals Announces Clinical Trial Collaboration with Bayer

2026-05-12 (ET)

07:20:00

Olema Oncology Anticipates OPERA-01 Trial Data Release

News

OLMA FAQ — answered by Alphio AI

Olema Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It is advancing a pipeline of novel therapies by leveraging its deep understanding of endocrine-driven cancers, nuclear receptors, and mechanisms of acquired resistance. Its lead product candidate, palazestrant (OP-1250), is a novel, orally available small molecule with dual activity as both a complete estrogen receptor (ER) antagonist (CERAN) and selective ER degrader (SERD). It is being investigated in patients with recurrent, locally advanced or metastatic ER-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer. Its second product candidate in clinical development, called OP-3136, is a novel, orally available small molecule that potently and selectively inhibits KAT6, an epigenetic target that is dysregulated in breast and other cancers. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Currently, Olema Pharmaceuticals Inc (OLMA) is not a good buy. The stock is trading at $7.82, significantly below its analyst price targets, which range from $20 to $59. However, the stock has a very low RSI of 14.106, indicating it is oversold, but the overall trend is negative with a year-to-date change of -69.07%. The main risk is its ongoing losses, with a net income of -$63.2 million reported for Q2 2026, which raises concerns about its financial sustainability.

Community

More ↗

No posts yet

Sign up or log in to join the discussion

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

Start trading