Orchestra Biomed Holdings Inc

Orchestra Biomed Holdings Inc (OBIO) Stock Analysis

$5.185

+0.076 (+1.47%)At close

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High
5.230
Open
5.230
VWAP
5.16
Vol
154.46K
Mkt Cap
283.80M
Low
5.060
Amount
796.74K
EV/EBITDA, TTM
-2.46

Orchestra BioMed Holdings, Inc. is a biomedical innovation company. The Company’s lead product candidates include Atrioventricular Interval Modulation (AVIM) therapy for the treatment of hypertension (HTN), the leading risk factor for death worldwide and the Virtue Sirolimus AngioInfusion Balloon (Virtue SAB) for the treatment of atherosclerotic artery disease, the leading cause of mortality worldwide. The Company develops bioelectronic therapies based on patented Cardiac Neuromodulation Therapy (CNT) technology. The AVIM is a bioelectronic therapy candidate designed to substantially and persistently lower blood pressure. Its Virtue SAB is a proprietary drug/device combination product candidate for the treatment of artery disease that is designed to deliver a proprietary, investigational, extended-release formulation of sirolimus (SirolimusEFR) to the vessel wall during balloon angioplasty without the need for balloon coating or a permanent implant.

AI analysis of Orchestra Biomed Holdings Inc (OBIO)

buy

Orchestra Biomed Holdings Inc is a good buy right now due to its current price of $5.185, which is significantly below the analyst price targets ranging from $10 to $13. The company has also shown a remarkable 89.23% increase over the past year, indicating strong long-term growth potential. However, investors should be cautious of the substantial net loss of $24.08 million reported in Q2 2026, which is a key risk factor.

Valuation Metrics

The current forward P/E ratio for Orchestra Biomed Holdings Inc (OBIO) is 0.00, compared to its 5-year average forward P/E of -3.12.

Forward P/E

Overvalued
5Y Average P/E
-3.12
Current P/E
0.00
Overvalued
-0.69
Undervalued
-5.54

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-1.78
Current EV/EBITDA
-2.46
Overvalued
88.10
Undervalued
-91.67

Forward P/S

Strongly Overvalued
5Y Average P/S
111.68
Current P/S
536.15
Overvalued
221.31
Undervalued
2.06

Alphio AI Price Scenarios for OBIO

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%OBIO

$6.39

Scenario price

B

Base

Base · 50%OBIO

$5.13

Scenario price

B

Bear

Bear · 25%OBIO

$4.69

Scenario price

Whales holding OBIO

M

Medtronic plc

+ HoldingOBIO

+35.38%

3M Return

R

RTW Investments, LP

+ HoldingOBIO

+15.57%

3M Return

P

Perceptive Advisors LLC

+ HoldingOBIO

+4.39%

3M Return

Events Timeline

2026-08-10 (ET)

17:30:00

Orchestra BioMed Q2 Revenue $88,000, Below Consensus

2026-05-12 (ET)

16:30:00

Orchestra BioMed Reports Q1 Revenue of $110,000

2026-05-06 (ET)

09:11:00

Orchestra BioMed Receives $15M Payment from Ligand

2026-04-30 (ET)

10:00:00

Orchestra BioMed Receives Second Breakthrough Device Designation from FDA

2026-03-12 (ET)

16:20:00

Major Averages Drop Over 1% Amid Iran War

News

OBIO FAQ — answered by Alphio AI

Orchestra BioMed Holdings, Inc. is a biomedical innovation company. The Company’s lead product candidates include Atrioventricular Interval Modulation (AVIM) therapy for the treatment of hypertension (HTN), the leading risk factor for death worldwide and the Virtue Sirolimus AngioInfusion Balloon (Virtue SAB) for the treatment of atherosclerotic artery disease, the leading cause of mortality worldwide. The Company develops bioelectronic therapies based on patented Cardiac Neuromodulation Therapy (CNT) technology. The AVIM is a bioelectronic therapy candidate designed to substantially and persistently lower blood pressure. Its Virtue SAB is a proprietary drug/device combination product candidate for the treatment of artery disease that is designed to deliver a proprietary, investigational, extended-release formulation of sirolimus (SirolimusEFR) to the vessel wall during balloon angioplasty without the need for balloon coating or a permanent implant. It operates in the Healthcare sector (SURGICAL & MEDICAL INSTRUMENTS & APPARATUS industry).

Orchestra Biomed Holdings Inc is a good buy right now due to its current price of $5.185, which is significantly below the analyst price targets ranging from $10 to $13. The company has also shown a remarkable 89.23% increase over the past year, indicating strong long-term growth potential. However, investors should be cautious of the substantial net loss of $24.08 million reported in Q2 2026, which is a key risk factor.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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