Neurogene Inc

Neurogene Inc (NGNE) Stock Analysis

$24.170

+0.957 (+3.96%)At close

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High
24.390
Open
23.260
VWAP
23.78
Volume
240.18K
Mkt Cap
—
Low
22.780
Amount
5.71M
EV/EBITDA, TTM
0.00

Neurogene Inc. is a clinical-stage biotechnology company. The Company, through its proprietary transgene regulation technology, Expression Attenuation via Construct Tuning (EXACT), is building a product portfolio of genetic medicines for rare neurological diseases with high unmet needs not otherwise addressable by conventional gene therapy. Its clinical-stage program, NGN-401, utilize the EXACT platform, which is in development for the treatment of Rett syndrome, a disease with a patient population that has a significant unmet need, and that ultimately progresses to substantial neurological and physical impairment and premature death. NGN-401 is being evaluated in female patients with Rett syndrome in a Phase 1/2 open-label, multi-center clinical trial that assesses the safety, tolerability, and efficacy of two doses of NGN-401 delivered using a one-time intracerebral ventricular (ICV) procedure. It is also developing NGN-101 for the treatment of CLN5 Batten disease.

AI analysis of Neurogene Inc (NGNE)

Buy

Neurogene Inc is a good buy right now due to its current price of $23.25, which is significantly lower than the analyst price target of $60 from JPMorgan, suggesting a potential upside of 132%. Additionally, the stock has a low RSI of 36.279, indicating it may be oversold, making it an attractive entry point for long-term investors. However, the company has reported substantial net losses, with a net income of -34,488,000 USD in Q2 2026, which remains a key risk.

Valuation Metrics

The current forward P/E ratio for Neurogene Inc (NGNE) is 0.00, compared to its 5-year average forward P/E of -6.03.

Forward P/E

Strongly Overvalued
5Y Average P/E
-6.03
Current P/E
0.00
Overvalued
-3.43
Undervalued
-8.64

Forward EV/EBITDA

Strongly Undervalued
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued
0.00
Undervalued
0.00

Forward P/S

Fair
5Y Average P/S
114.42
Current P/S
0.00
Overvalued
430.16
Undervalued
-201.32

Alphio AI Price Scenarios for NGNE

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%NGNE

$24.10

Scenario price

B

Base

Base · 50%NGNE

$23.77

Scenario price

B

Bear

Bear · 25%NGNE

$21.90

Scenario price

Whales holding NGNE

C

Casdin Capital, LLC

+ HoldingNGNE

-4.73%

3M Return

R

RTW Investments, LP

+ HoldingNGNE

-10.67%

3M Return

E

EcoR1 Capital, LLC

+ HoldingNGNE

-11.59%

3M Return

Events Timeline

2026-10-18 (ET)

21:00:00

Chewy Short Interest Surges to 91.3%

2026-08-11 (ET)

08:00:00

Neurogene's NGN-401 Program Achieves Significant Progress

2026-07-10 (ET)

22:00:00

Ondas Holdings Short Interest Rises to 40%

2026-07-01 (ET)

07:30:00

Neurogene Prices Public Offering at $30 per Share

2026-06-30 (ET)

19:00:00

Leerink and Others Act as Joint Book Running Managers for Offering

News

NGNE FAQ — answered by Alphio AI

Neurogene Inc. is a clinical-stage biotechnology company. The Company, through its proprietary transgene regulation technology, Expression Attenuation via Construct Tuning (EXACT), is building a product portfolio of genetic medicines for rare neurological diseases with high unmet needs not otherwise addressable by conventional gene therapy. Its clinical-stage program, NGN-401, utilize the EXACT platform, which is in development for the treatment of Rett syndrome, a disease with a patient population that has a significant unmet need, and that ultimately progresses to substantial neurological and physical impairment and premature death. NGN-401 is being evaluated in female patients with Rett syndrome in a Phase 1/2 open-label, multi-center clinical trial that assesses the safety, tolerability, and efficacy of two doses of NGN-401 delivered using a one-time intracerebral ventricular (ICV) procedure. It is also developing NGN-101 for the treatment of CLN5 Batten disease. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Neurogene Inc is a good buy right now due to its current price of $23.25, which is significantly lower than the analyst price target of $60 from JPMorgan, suggesting a potential upside of 132%. Additionally, the stock has a low RSI of 36.279, indicating it may be oversold, making it an attractive entry point for long-term investors. However, the company has reported substantial net losses, with a net income of -34,488,000 USD in Q2 2026, which remains a key risk.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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