Lexicon Pharmaceuticals Inc

Lexicon Pharmaceuticals Inc (LXRX) Stock Analysis

$1.520

-0.120 (-7.88%)At close

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High
1.680
Open
1.680
VWAP
1.57
Volume
2.01M
Mkt Cap
629.00M
Low
1.520
Amount
3.17M
EV/EBITDA, TTM
-1.16

Lexicon Pharmaceuticals, Inc., is a biopharmaceutical company. The Company is engaged in research and development of drug candidates and the commercialization of the drug, INPEFA (sotagliflozin). INPEFA reduces the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease (CKD), and other cardiovascular risk factors. Sotagliflozin is an orally delivered small molecule drug candidate as a treatment for hypertrophic cardiomyopathy (HCM) and conducts the SONATA-HCM pivotal Phase 3 clinical trial of sotagliflozin in that indication. The Company develops pilavapadin, an orally delivered small molecule drug candidate, as a treatment for neuropathic pain. The Company also develops LX9851, an orally delivered small molecule drug candidate, for the treatment of obesity and associated cardiometabolic disorders.

AI analysis of Lexicon Pharmaceuticals Inc (LXRX)

Hold

Lexicon Pharmaceuticals Inc (LXRX) is currently trading at $1.52, which is significantly below the analyst price target of $8, indicating a potential upside of over 400%. However, the stock has a very low RSI of 19.53, suggesting it is oversold, but it has also experienced a 25.85% decline over the past 20 days, indicating bearish momentum. The main risk is the company's negative earnings trend, with a net income loss of $31.77 million reported in Q2 2026, which raises concerns about its financial stability.

Analyst Ratings (7)

+165.13% upside
Buy
4 Buy
3 Hold
0 Sell
Current: 1.52
Low
2.10
Average
4.03
High
6.00

Cantor Fitzgerald

2026-09-28

Price Target

$8

Overweight

Citi

2026-05-11

Price Target

—

Buy

Citi

2026-03-10

Price Target

—

Buy

H.C. Wainwright

2026-03-05

Price Target

$6

Buy

Citi

2025-08-07

Price Target

—

Buy

Valuation Metrics

The current forward P/E ratio for Lexicon Pharmaceuticals Inc (LXRX) is 0.00, compared to its 5-year average forward P/E of -3.18.

Forward P/E

Strongly Overvalued
5Y Average P/E
-3.18
Current P/E
0.00
Overvalued
-1.70
Undervalued
-4.66

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-117.18
Current EV/EBITDA
-1.16
Overvalued
402.55
Undervalued
-636.91

Forward P/S

Fair
5Y Average P/S
439.53
Current P/S
43.35
Overvalued
1681.41
Undervalued
-802.35

Alphio AI Price Scenarios for LXRX

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%LXRX

$2.20

Scenario price

B

Base

Base · 50%LXRX

$1.69

Scenario price

B

Bear

Bear · 25%LXRX

$1.46

Scenario price

Whales holding LXRX

S

Sessa Capital IM, L.P.

+ HoldingLXRX

-13.55%

3M Return

Events Timeline

2026-09-28 (ET)

12:00:00

Major Averages Broadly Lower as Oil Prices Surge Over 3%

2026-08-31 (ET)

09:00:00

Lexicon Announces Heart Failure Drug Study Results

2026-08-24 (ET)

09:00:00

Lexicon Earns $10M Milestone Payment from Novo Nordisk

2026-08-06 (ET)

17:30:00

Selling Stockholders Plan to Sell 1.26M Shares of Common Stock

2026-07-27 (ET)

09:30:00

Lexicon Completes Patient Randomization in SOtaglifloziN Clinical Trial

News

LXRX FAQ — answered by Alphio AI

Lexicon Pharmaceuticals, Inc., is a biopharmaceutical company. The Company is engaged in research and development of drug candidates and the commercialization of the drug, INPEFA (sotagliflozin). INPEFA reduces the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease (CKD), and other cardiovascular risk factors. Sotagliflozin is an orally delivered small molecule drug candidate as a treatment for hypertrophic cardiomyopathy (HCM) and conducts the SONATA-HCM pivotal Phase 3 clinical trial of sotagliflozin in that indication. The Company develops pilavapadin, an orally delivered small molecule drug candidate, as a treatment for neuropathic pain. The Company also develops LX9851, an orally delivered small molecule drug candidate, for the treatment of obesity and associated cardiometabolic disorders. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Lexicon Pharmaceuticals Inc (LXRX) is currently trading at $1.52, which is significantly below the analyst price target of $8, indicating a potential upside of over 400%. However, the stock has a very low RSI of 19.53, suggesting it is oversold, but it has also experienced a 25.85% decline over the past 20 days, indicating bearish momentum. The main risk is the company's negative earnings trend, with a net income loss of $31.77 million reported in Q2 2026, which raises concerns about its financial stability.

7 analysts cover LXRX: 4 rate it Buy, 3 Hold and 0 Sell. The average price target is 4.03.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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