Lexicon Pharmaceuticals Inc

Lexicon Pharmaceuticals Inc (LXRX) Stock Analysis

$2.290

-0.030 (-1.29%)At close

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High
2.320
Open
2.300
VWAP
2.29
Vol
2.68M
Mkt Cap
629.00M
Low
2.260
Amount
6.14M
EV/EBITDA, TTM
-1.38

Lexicon Pharmaceuticals, Inc., is a biopharmaceutical company. The Company is engaged in research and development of drug candidates and the commercialization of the drug, INPEFA (sotagliflozin). INPEFA reduces the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease (CKD), and other cardiovascular risk factors. Sotagliflozin is an orally delivered small molecule drug candidate as a treatment for hypertrophic cardiomyopathy (HCM) and conducts the SONATA-HCM pivotal Phase 3 clinical trial of sotagliflozin in that indication. The Company develops pilavapadin, an orally delivered small molecule drug candidate, as a treatment for neuropathic pain. The Company also develops LX9851, an orally delivered small molecule drug candidate, for the treatment of obesity and associated cardiometabolic disorders.

AI analysis of Lexicon Pharmaceuticals Inc (LXRX)

buy

Lexicon Pharmaceuticals (LXRX) is a good buy right now due to its recent milestone payment of $10 million from Novo Nordisk, contributing to a total of $75 million in milestone payments, indicating strong collaboration and growth potential. The current price of $2.29 is significantly below the analyst price target of $3.10, suggesting a potential upside of 35.4%. Additionally, the company has shown a remarkable year-to-date change of +100.88%, reflecting strong investor interest and optimism about its future prospects. However, the main risk is the high negative net income reported for Q2 2026 at -31.77 million USD, which highlights ongoing financial challenges that investors should monitor closely.

Analyst Ratings (7)

+75.98% upside
Buy
4 Buy
3 Hold
0 Sell
Current: 2.29
Low
2.10
Average
4.03
High
6.00

Citi

2026-05-11

Price Target

Buy

Citi

2026-03-10

Price Target

Buy

H.C. Wainwright

2026-03-05

Price Target

$6

Buy

Citi

2025-08-07

Price Target

Buy

HC Wainwright & Co.

2025-03-28

Price Target

$4

Strong Buy

Valuation Metrics

The current forward P/E ratio for Lexicon Pharmaceuticals Inc (LXRX) is 0.00, compared to its 5-year average forward P/E of -3.32.

Forward P/E

Strongly Overvalued
5Y Average P/E
-3.32
Current P/E
0.00
Overvalued
-1.66
Undervalued
-4.98

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-117.65
Current EV/EBITDA
-1.38
Overvalued
402.42
Undervalued
-637.71

Forward P/S

Fair
5Y Average P/S
439.53
Current P/S
51.84
Overvalued
1682.51
Undervalued
-803.46

Alphio AI Price Scenarios for LXRX

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%LXRX

$2.20

Scenario price

B

Base

Base · 50%LXRX

$1.69

Scenario price

B

Bear

Bear · 25%LXRX

$1.46

Scenario price

Whales holding LXRX

S

Sessa Capital IM, L.P.

+ HoldingLXRX

+12.89%

3M Return

A

Artal Group S.A.

+ HoldingLXRX

-0.61%

3M Return

Events Timeline

2026-08-24 (ET)

09:00:00

Lexicon Earns $10M Milestone Payment from Novo Nordisk

2026-08-06 (ET)

17:30:00

Selling Stockholders Plan to Sell 1.26M Shares of Common Stock

2026-07-27 (ET)

09:30:00

Lexicon Completes Patient Randomization in SOtaglifloziN Clinical Trial

2026-05-07 (ET)

09:20:00

Company Reports Q1 Revenue of $21.1M, Exceeds Expectations

2026-04-17 (ET)

08:20:00

Lexicon Pharmaceuticals to Present Pilavapadin Study Results at AAN Meeting

News

LXRX FAQ — answered by Alphio AI

Lexicon Pharmaceuticals, Inc., is a biopharmaceutical company. The Company is engaged in research and development of drug candidates and the commercialization of the drug, INPEFA (sotagliflozin). INPEFA reduces the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease (CKD), and other cardiovascular risk factors. Sotagliflozin is an orally delivered small molecule drug candidate as a treatment for hypertrophic cardiomyopathy (HCM) and conducts the SONATA-HCM pivotal Phase 3 clinical trial of sotagliflozin in that indication. The Company develops pilavapadin, an orally delivered small molecule drug candidate, as a treatment for neuropathic pain. The Company also develops LX9851, an orally delivered small molecule drug candidate, for the treatment of obesity and associated cardiometabolic disorders. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Lexicon Pharmaceuticals (LXRX) is a good buy right now due to its recent milestone payment of $10 million from Novo Nordisk, contributing to a total of $75 million in milestone payments, indicating strong collaboration and growth potential. The current price of $2.29 is significantly below the analyst price target of $3.10, suggesting a potential upside of 35.4%. Additionally, the company has shown a remarkable year-to-date change of +100.88%, reflecting strong investor interest and optimism about its future prospects. However, the main risk is the high negative net income reported for Q2 2026 at -31.77 million USD, which highlights ongoing financial challenges that investors should monitor closely.

7 analysts cover LXRX: 4 rate it Buy, 3 Hold and 0 Sell. The average price target is 4.03.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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