Kyverna Therapeutics Inc

Kyverna Therapeutics Inc (KYTX) Stock Analysis

$5.730

-0.108 (-1.88%)At close

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High
5.985
Open
5.825
VWAP
5.80
Volume
518.50K
Mkt Cap
—
Low
5.670
Amount
3.00M
EV/EBITDA, TTM
0.00

Kyverna Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing cell therapies for patients with autoimmune diseases. The Company’s lead chimeric antigen receptor (CAR) T-cell therapy candidate, KYV-101, is advancing through clinical development with Phase II trials for stiff person syndrome and myasthenia gravis, and two ongoing multi-center Phase I/II trials for patients with lupus nephritis. KYV-101 is an autologous, fully human CD19 CAR T-cell product candidate incorporating highly potent CD28 co-stimulation. The Company is also harnessing investigator-initiated trials and other KYSA studies, including in multiple sclerosis and systemic sclerosis, to inform the next priority indications for the Company to advance into late-stage development. Its pipeline includes next generation CAR T-cell therapies in both autologous and allogeneic formats with properties intended to be well suited for use in B cell-driven autoimmune diseases.

kyvernatx.com

AI analysis of Kyverna Therapeutics Inc (KYTX)

Sell

Kyverna Therapeutics Inc is not a good buy right now due to its current price of $5.67, which is significantly below the analyst price targets of $25 and $29. However, the stock has seen a 35.35% decline year-to-date, indicating potential for recovery. The RSI is at 29.778, suggesting the stock is oversold, but the negative earnings trend with a forward P/E of 0 and consistent losses (latest EPS reported at -0.63) raises concerns about its financial health. The main risk is the ongoing net losses, with a net income of -39,728,000 USD in Q1 2026, which could hinder future growth and recovery.

Valuation Metrics

The current forward P/E ratio for Kyverna Therapeutics Inc (KYTX) is 0.00, compared to its 5-year average forward P/E of -2.51.

Forward P/E

Overvalued
5Y Average P/E
-2.51
Current P/E
0.00
Overvalued
-0.21
Undervalued
-4.81

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-0.89
Current EV/EBITDA
0.00
Overvalued
1.98
Undervalued
-3.77

Forward P/S

Fair
5Y Average P/S
9.51
Current P/S
21.72
Overvalued
24.42
Undervalued
-5.41

Alphio AI Price Scenarios for KYTX

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%KYTX

$4.24

Scenario price

B

Base

Base · 50%KYTX

$3.52

Scenario price

B

Bear

Bear · 25%KYTX

$3.43

Scenario price

Whales holding KYTX

I

Insight Venture Management, LLC

+ HoldingKYTX

+6.37%

3M Return

G

Gilead Sciences, Inc.

+ HoldingKYTX

-26.12%

3M Return

Events Timeline

2026-09-24 (ET)

06:30:00

Kyverna Therapeutics Reports Positive One-Year Data from KYSA-8

2026-08-11 (ET)

16:30:00

Kyverna Advances BLA Submission and Clinical Trials

2026-07-27 (ET)

08:30:00

Kyverna and ElevateBio Sign Manufacturing Agreement for miv-cel

2026-07-13 (ET)

09:00:00

Cue Biopharma Appoints Dominic Borie as Chief Medical Officer

2026-07-09 (ET)

08:30:00

Vera Therapeutics Chief Regulatory Officer William Turner Retires, Nancy Boman Succeeds

News

KYTX FAQ — answered by Alphio AI

Kyverna Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing cell therapies for patients with autoimmune diseases. The Company’s lead chimeric antigen receptor (CAR) T-cell therapy candidate, KYV-101, is advancing through clinical development with Phase II trials for stiff person syndrome and myasthenia gravis, and two ongoing multi-center Phase I/II trials for patients with lupus nephritis. KYV-101 is an autologous, fully human CD19 CAR T-cell product candidate incorporating highly potent CD28 co-stimulation. The Company is also harnessing investigator-initiated trials and other KYSA studies, including in multiple sclerosis and systemic sclerosis, to inform the next priority indications for the Company to advance into late-stage development. Its pipeline includes next generation CAR T-cell therapies in both autologous and allogeneic formats with properties intended to be well suited for use in B cell-driven autoimmune diseases. It operates in the Healthcare sector (BIOLOGICAL PRODUCTS, EXCEPT DIAGNOSTIC SUBSTANCES industry).

Kyverna Therapeutics Inc is not a good buy right now due to its current price of $5.67, which is significantly below the analyst price targets of $25 and $29. However, the stock has seen a 35.35% decline year-to-date, indicating potential for recovery. The RSI is at 29.778, suggesting the stock is oversold, but the negative earnings trend with a forward P/E of 0 and consistent losses (latest EPS reported at -0.63) raises concerns about its financial health. The main risk is the ongoing net losses, with a net income of -39,728,000 USD in Q1 2026, which could hinder future growth and recovery.

Community

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0xLunarbazaar9/24/2026

$KYTX Swarmer's miv-cel shows positive results in stiff person syndrome and gMG Kyverna Therapeutics announced positive one-year topline data from KYSA-8, its registrational trial of miv-cel - mivocabtagene autoleucel, KYV-101 - in patients with stiff person syndrome or SPS, and positive topline longer-term follow-up data from the Phase 2 portion of KYSA-6, its registrational trial in patients with generalized myasthenia gravis, or gMG. Data from both trials will be shared at upcoming medical meetings. The primary endpoint and all key secondary endpoints were achieved with statistical significance in KYSA-8. The topline one-year durability data further strengthen the positive results. Miv-cel continued to be well-tolerated. Longer-term Phase 2 follow-up in gMG demonstrate robust and durable effects sustained for up to 1.5 years, with majority of patients maintaining MSE. Kyverna intends to include the one-year data in its rolling BLA submission, on track to be completed in Q4. The full data set will be presented at MS Toronto, October 21-23, in Toronto. All 7 patients achieved clinically meaningful improvement in MG-ADL and QMG, co-primary endpoints of the ongoing Phase 3 portion. All 7 patients remained free of immunotherapies for MG. Miv-cel continued to be well-tolerated. The Phase 3 portion of the KYSA-6 trial is ongoing, with enrollment expected to be completed in mid-2027.

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