Krystal Biotech Inc

Krystal Biotech Inc (KRYS) Stock Analysis

$325.420

+5.239 (+1.61%)At close

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High
328.760
Open
321.800
VWAP
325.15
Volume
195.45K
Mkt Cap
5.22B
Low
321.260
Amount
63.55M
EV/EBITDA, TTM
28.36

Krystal Biotech, Inc. is an integrated, commercial-stage biotechnology company. The Company is focused on the discovery, development, and commercialization of genetic medicines to treat diseases with high unmet medical needs. Its product candidates in various stages of clinical and preclinical development include KB407, KB408, KB707, KB105, KB801, KB803, KB304 and KB301. Its commercial product, VYJUVEK, is a redosable gene therapy, and a genetic medicine approved in the United States and Europe for the treatment of dystrophic epidermolysis bullosa. KB407 is being developed for the treatment of Cystic Fibrosis. KB408 is being developed for the treatment of Alpha-1 Antitrypsin Deficiency, a rare lung disease. KB707 is being developed for the treatment of solid tumors. KB105 is being developed for TGM1-Deficient Autosomal Recessive Congenital Ichthyosis. KB803 is a redosable eye drop formulation of B-VEC, designed for the treatment of ocular complications.

AI analysis of Krystal Biotech Inc (KRYS)

Hold

Krystal Biotech Inc is currently not a strong buy due to its recent price decline and technical indicators, despite a solid long-term growth outlook. The current price is $316.58, and the RSI is at 33.005, indicating oversold conditions. However, the forward P/E ratio is high at 46.9484, suggesting that the stock may be overvalued at this time. The main risk is the recent price drop of 4.53% over the last five days, which could indicate bearish sentiment in the short term.

Analyst Ratings (1)

-29.55% Downside
Buy
1 Buy
0 Hold
0 Sell
Current: 325.42
Low
198.00
Average
229.25
High
278.00

BofA

2026-09-21

Price Target

$400

Buy

BofA

2026-08-04

Price Target

$392

Buy

Citi

2026-08-04

Price Target

$386

Buy

BofA

2026-07-14

Price Target

$396

Buy

TD Cowen

2026-06-18

Price Target

$403

Buy

Valuation Metrics

The current forward P/E ratio for Krystal Biotech Inc (KRYS) is 46.95, compared to its 5-year average forward P/E of -3.60.

Forward P/E

Fair
5Y Average P/E
-3.60
Current P/E
46.95
Overvalued
66.94
Undervalued
-74.13

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
20.42
Current EV/EBITDA
28.36
Overvalued
64.87
Undervalued
-24.04

Forward P/S

Fair
5Y Average P/S
139.97
Current P/S
14.85
Overvalued
676.28
Undervalued
-396.33

Alphio AI Price Scenarios for KRYS

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%KRYS

$429.67

Scenario price

B

Base

Base · 50%KRYS

$283.64

Scenario price

B

Bear

Bear · 25%KRYS

$273.98

Scenario price

Whales holding KRYS

B

Braidwell LP

+ HoldingKRYS

+22.04%

3M Return

B

Bellevue Asset Management AG

+ HoldingKRYS

+0.71%

3M Return

S

Soleus Capital Management, L.P.

+ HoldingKRYSUTHR

-10.94%

3M Return

H

Hood River Capital Management LLC

+ HoldingKRYS

-11.98%

3M Return

Events Timeline

2026-10-15 (ET)

07:30:00

Krystal Biotech Provides Clinical Update on KB113 Efficacy

2026-08-03 (ET)

09:30:00

Stock Futures Rise as Investors Improve Risk Appetite

08:00:00

Krystal Biotech Q2 Revenue $119.22M, Below Consensus

2026-07-20 (ET)

17:30:00

Berkshire Hathaway Acquires Taylor Morrison Home

2026-05-18 (ET)

08:20:00

Krystal Biotech Receives UK Approval for Vyjuvek to Treat Skin Disease

News

KRYS FAQ — answered by Alphio AI

Krystal Biotech, Inc. is an integrated, commercial-stage biotechnology company. The Company is focused on the discovery, development, and commercialization of genetic medicines to treat diseases with high unmet medical needs. Its product candidates in various stages of clinical and preclinical development include KB407, KB408, KB707, KB105, KB801, KB803, KB304 and KB301. Its commercial product, VYJUVEK, is a redosable gene therapy, and a genetic medicine approved in the United States and Europe for the treatment of dystrophic epidermolysis bullosa. KB407 is being developed for the treatment of Cystic Fibrosis. KB408 is being developed for the treatment of Alpha-1 Antitrypsin Deficiency, a rare lung disease. KB707 is being developed for the treatment of solid tumors. KB105 is being developed for TGM1-Deficient Autosomal Recessive Congenital Ichthyosis. KB803 is a redosable eye drop formulation of B-VEC, designed for the treatment of ocular complications. It operates in the Healthcare sector (BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES) industry).

Krystal Biotech Inc is currently not a strong buy due to its recent price decline and technical indicators, despite a solid long-term growth outlook. The current price is $316.58, and the RSI is at 33.005, indicating oversold conditions. However, the forward P/E ratio is high at 46.9484, suggesting that the stock may be overvalued at this time. The main risk is the recent price drop of 4.53% over the last five days, which could indicate bearish sentiment in the short term.

1 analysts cover KRYS: 1 rate it Buy, 0 Hold and 0 Sell. The average price target is 229.25.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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