Jazz Pharmaceuticals PLC

Jazz Pharmaceuticals PLC (JAZZ) Stock Analysis

$244.540

-6.382 (-2.61%)At close

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High
250.640
Open
249.480
VWAP
246.56
Vol
1.19M
Mkt Cap
6.75B
Low
244.490
Amount
294.16M
EV/EBITDA, TTM
8.00

Jazz Pharmaceuticals plc is a global biopharmaceutical company. It is engaged in developing medicines for people with serious diseases, often with limited or no therapeutic options. It has a diverse portfolio of marketed medicines, including therapies for sleep disorders and epilepsy, and a portfolio of cancer treatments. Its lead-marketed products include Xywav (calcium, magnesium, potassium, and sodium oxybates) oral solution, Epidiolex (cannabidiol) oral solution, Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn), Zepzelca (lurbinectedin), Ziihera (zanidatamab-hrii), and Enrylaze (recombinant crisantaspase). Its product candidates include Zanidatamab, Vyxeos, JZP815, JZP898, JZP441, and others. Xywav is used for the treatment of cataplexy or EDS in patients seven years of age and older with narcolepsy. The Company, through Chimerix, Inc., also owns a clinical asset, dordaviprone, a novel small molecule treatment in development for H3 K27M-mutant diffuse glioma.

AI analysis of Jazz Pharmaceuticals PLC (JAZZ)

buy

Jazz Pharmaceuticals appears to be a good buy right now due to its strong growth potential driven by the recent FDA approval of Ziihera, which has increased peak sales forecasts to $3B-$5B. The current price of $244.54 is well below the average analyst price target of $299, suggesting significant upside potential. Additionally, the company's gross margin has improved to 76.30% in Q2 2026, indicating strong profitability. However, the main risk is the negative earnings per share of -1.52 in Q1 2025, which highlights past volatility in earnings.

Analyst Ratings (21)

-10.48% downside
Buy
16 Buy
5 Hold
0 Sell
Current: 244.54
Low
188.00
Average
218.92
High
263.00

RBC Capital

2026-08-28

Price Target

$299

Outperform

Morgan Stanley

2026-08-26

Price Target

$322

Overweight

Truist

2026-08-26

Price Target

$281

Buy

Needham

2026-08-26

Price Target

$310

Buy

Deutsche Bank

2026-08-26

Price Target

$300

Buy

Valuation Metrics

The current forward P/E ratio for Jazz Pharmaceuticals PLC (JAZZ) is 18.83, compared to its 5-year average forward P/E of 7.79.

Forward P/E

Strongly Overvalued
5Y Average P/E
7.79
Current P/E
18.83
Overvalued
10.25
Undervalued
5.32

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
8.49
Current EV/EBITDA
8.00
Overvalued
12.65
Undervalued
4.33

Forward P/S

Strongly Overvalued
5Y Average P/S
2.17
Current P/S
3.27
Overvalued
2.60
Undervalued
1.73

Alphio AI Price Scenarios for JAZZ

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%JAZZ

$101.77

Scenario price

B

Base

Base · 50%JAZZ

$95.48

Scenario price

B

Bear

Bear · 25%JAZZ

$78.69

Scenario price

Whales holding JAZZ

S

Sofinnova Investments, Inc.

+ HoldingJAZZ

+15.48%

3M Return

P

Pacific Investment Management Company LLC

+ HoldingJAZZ

+4.81%

3M Return

P

Perceptive Advisors LLC

+ HoldingJAZZ

+4.39%

3M Return

L

LSV Asset Management

+ HoldingJAZZ

+1.61%

3M Return

G

GMT Capital Corp.

+ HoldingJAZZ

-2.06%

3M Return

H

Hennion & Walsh Asset Management, Inc.

+ HoldingJAZZ

-3.94%

3M Return

Events Timeline

2026-08-27 (ET)

08:00:00

Jazz Pharmaceuticals Prices $1.1 Billion Exchangeable Senior Notes

2026-08-26 (ET)

15:00:00

Roche Receives FDA Approval for Expanded HER2 Testing

2026-08-25 (ET)

11:00:00

BeOne Medicines' TEVIMBRA Approved by FDA for HER2 Positive Gastric Cancer

10:30:00

Zymeworks' Partner Jazz Receives FDA Approval for Ziihera Regimens

10:30:00

Jazz Pharmaceuticals' Ziihera Approved by FDA for HER2-Positive Gastric Cancer Treatment

News

JAZZ FAQ — answered by Alphio AI

Jazz Pharmaceuticals plc is a global biopharmaceutical company. It is engaged in developing medicines for people with serious diseases, often with limited or no therapeutic options. It has a diverse portfolio of marketed medicines, including therapies for sleep disorders and epilepsy, and a portfolio of cancer treatments. Its lead-marketed products include Xywav (calcium, magnesium, potassium, and sodium oxybates) oral solution, Epidiolex (cannabidiol) oral solution, Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn), Zepzelca (lurbinectedin), Ziihera (zanidatamab-hrii), and Enrylaze (recombinant crisantaspase). Its product candidates include Zanidatamab, Vyxeos, JZP815, JZP898, JZP441, and others. Xywav is used for the treatment of cataplexy or EDS in patients seven years of age and older with narcolepsy. The Company, through Chimerix, Inc., also owns a clinical asset, dordaviprone, a novel small molecule treatment in development for H3 K27M-mutant diffuse glioma. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Jazz Pharmaceuticals appears to be a good buy right now due to its strong growth potential driven by the recent FDA approval of Ziihera, which has increased peak sales forecasts to $3B-$5B. The current price of $244.54 is well below the average analyst price target of $299, suggesting significant upside potential. Additionally, the company's gross margin has improved to 76.30% in Q2 2026, indicating strong profitability. However, the main risk is the negative earnings per share of -1.52 in Q1 2025, which highlights past volatility in earnings.

21 analysts cover JAZZ: 16 rate it Buy, 5 Hold and 0 Sell. The average price target is 218.92.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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