Structure Therapeutics Inc

Structure Therapeutics Inc (GPCR) Stock Analysis

$22.190

+0.315 (+1.42%)At close

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High
22.615
Open
21.890
VWAP
22.20
Volume
1.41M
Mkt Cap
2.23B
Low
21.810
Amount
31.40M
EV/EBITDA, TTM
0.00

Structure Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing oral small molecule treatments for chronic metabolic and cardiopulmonary conditions with significant unmet medical needs. Its programs include Aleniglipron (GSBR-1290), ACCG-2671, GIP and GCG Receptor Oral Small Molecule Obesity Programs, ANPA-0073, and LTSE-2578. Its Aleniglipron is an oral and biased small molecule agonist of GLP-1R, a validated GPCR drug target for obesity. ACCG-2671 is an oral small molecule amylin receptor agonist for obesity. ANPA-0073 is a biased agonist targeting the apelin (APJ) receptor agonist. Its LTSE-2578, an Oral Small Molecule LPA1R Antagonist for IPF. It is developing an antagonist that targets lysophosphatidic acid 1 receptor (LPA1R), a GPCR implicated in responses to tissue injury and pro-fibrotic processes, for the treatment of IPF. It is developing oral incretins for potential combination therapy with GLP-1R or amylin candidates.

AI analysis of Structure Therapeutics Inc (GPCR)

Hold

Structure Therapeutics Inc (GPCR) is not a good buy right now due to its current price of $25.54, which is significantly lower than the average analyst price target of $110. Additionally, the stock has seen a year-to-date change of -62.51%, indicating a strong downtrend. The RSI is at an extremely low 4.53, suggesting oversold conditions, but this could also indicate continued weakness. The main risk is the negative earnings trend, with EPS reported at -0.49, reflecting ongoing losses.

Valuation Metrics

The current forward P/E ratio for Structure Therapeutics Inc (GPCR) is 0.00, compared to its 5-year average forward P/E of -34.31.

Forward P/E

Strongly Overvalued
5Y Average P/E
-34.31
Current P/E
0.00
Overvalued
-20.41
Undervalued
-48.22

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-3.95
Current EV/EBITDA
0.00
Overvalued
0.19
Undervalued
-8.09

Forward P/S

Fair
5Y Average P/S
17961.09
Current P/S
35003.80
Overvalued
53671.30
Undervalued
-17749.13

Alphio AI Price Scenarios for GPCR

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%GPCR

$24.61

Scenario price

B

Base

Base · 50%GPCR

$22.10

Scenario price

B

Bear

Bear · 25%GPCR

$20.36

Scenario price

Whales holding GPCR

D

Deerfield Management Company, L.P.

+ HoldingGPCR

-6.90%

3M Return

R

RTW Investments, LP

+ HoldingGPCR

-8.29%

3M Return

H

HongShan Capital Advisors Limited

+ HoldingGPCR

-8.57%

3M Return

R

Rock Springs Capital Management LP

+ HoldingGPCR

-9.08%

3M Return

O

OrbiMed Advisors LLC

+ HoldingGPCR

-10.38%

3M Return

Events Timeline

2026-09-08 (ET)

08:30:00

Structure Therapeutics Reports Clinical Trial Results for ACCG-2671 and Aleniglipron

2026-06-05 (ET)

16:10:00

Structure Therapeutics Publishes Phase 2b Trial Results for Aleniglipron

2026-04-14 (ET)

16:20:00

Structure Therapeutics Appoints Matthew Lang as COO and General Counsel

2026-03-16 (ET)

07:20:00

Structure Therapeutics Announces Aleniglipron Clinical Data

News

GPCR FAQ — answered by Alphio AI

Structure Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing oral small molecule treatments for chronic metabolic and cardiopulmonary conditions with significant unmet medical needs. Its programs include Aleniglipron (GSBR-1290), ACCG-2671, GIP and GCG Receptor Oral Small Molecule Obesity Programs, ANPA-0073, and LTSE-2578. Its Aleniglipron is an oral and biased small molecule agonist of GLP-1R, a validated GPCR drug target for obesity. ACCG-2671 is an oral small molecule amylin receptor agonist for obesity. ANPA-0073 is a biased agonist targeting the apelin (APJ) receptor agonist. Its LTSE-2578, an Oral Small Molecule LPA1R Antagonist for IPF. It is developing an antagonist that targets lysophosphatidic acid 1 receptor (LPA1R), a GPCR implicated in responses to tissue injury and pro-fibrotic processes, for the treatment of IPF. It is developing oral incretins for potential combination therapy with GLP-1R or amylin candidates. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Structure Therapeutics Inc (GPCR) is not a good buy right now due to its current price of $25.54, which is significantly lower than the average analyst price target of $110. Additionally, the stock has seen a year-to-date change of -62.51%, indicating a strong downtrend. The RSI is at an extremely low 4.53, suggesting oversold conditions, but this could also indicate continued weakness. The main risk is the negative earnings trend, with EPS reported at -0.49, reflecting ongoing losses.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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