Structure Therapeutics Inc

Structure Therapeutics Inc (GPCR) Stock Analysis

$47.370

-1.781 (-3.76%)At close

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High
49.200
Open
48.930
VWAP
47.84
Vol
601.77K
Mkt Cap
2.23B
Low
46.960
Amount
28.79M
EV/EBITDA, TTM
0.00

Structure Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing oral small molecule treatments for chronic metabolic and cardiopulmonary conditions with significant unmet medical needs. Its programs include Aleniglipron (GSBR-1290), ACCG-2671, GIP and GCG Receptor Oral Small Molecule Obesity Programs, ANPA-0073, and LTSE-2578. Its Aleniglipron is an oral and biased small molecule agonist of GLP-1R, a validated GPCR drug target for obesity. ACCG-2671 is an oral small molecule amylin receptor agonist for obesity. ANPA-0073 is a biased agonist targeting the apelin (APJ) receptor agonist. Its LTSE-2578, an Oral Small Molecule LPA1R Antagonist for IPF. It is developing an antagonist that targets lysophosphatidic acid 1 receptor (LPA1R), a GPCR implicated in responses to tissue injury and pro-fibrotic processes, for the treatment of IPF. It is developing oral incretins for potential combination therapy with GLP-1R or amylin candidates.

AI analysis of Structure Therapeutics Inc (GPCR)

hold

Structure Therapeutics Inc (GPCR) is currently priced at $47.37, which is significantly lower than the analyst price target of $111 from Canaccord. However, the stock has a low RSI of 22.854, indicating it is oversold, but it also has a negative forward P/E ratio of 0, suggesting uncertainty about future earnings. The main risk is the declining net income, with a loss of $106,159,000 reported in Q2 2026, which raises concerns about the company's financial health.

Valuation Metrics

The current forward P/E ratio for Structure Therapeutics Inc (GPCR) is 0.00, compared to its 5-year average forward P/E of -34.31.

Forward P/E

Strongly Overvalued
5Y Average P/E
-34.31
Current P/E
0.00
Overvalued
-20.41
Undervalued
-48.22

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-3.95
Current EV/EBITDA
0.00
Overvalued
0.19
Undervalued
-8.09

Forward P/S

Overvalued
5Y Average P/S
16404.92
Current P/S
84230.17
Overvalued
51717.29
Undervalued
-18907.45

Alphio AI Price Scenarios for GPCR

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%GPCR

$24.61

Scenario price

B

Base

Base · 50%GPCR

$22.10

Scenario price

B

Bear

Bear · 25%GPCR

$20.36

Scenario price

Whales holding GPCR

B

Baker Bros. Advisors LP

+ HoldingGPCR

+18.95%

3M Return

R

Rock Springs Capital Management LP

+ HoldingGPCR

+18.51%

3M Return

L

Logos Global Management, L.P.

+ HoldingGPCR

+17.53%

3M Return

A

Avoro Capital Advisors LLC

+ HoldingGPCR

+13.10%

3M Return

B

BVF Partners L.P.

+ HoldingGPCR

+11.78%

3M Return

O

OrbiMed Advisors LLC

+ HoldingGPCR

+5.01%

3M Return

Events Timeline

2026-06-05 (ET)

16:10:00

Structure Therapeutics Publishes Phase 2b Trial Results for Aleniglipron

2026-04-14 (ET)

16:20:00

Structure Therapeutics Appoints Matthew Lang as COO and General Counsel

2026-03-16 (ET)

07:20:00

Structure Therapeutics Announces Aleniglipron Clinical Data

2026-01-30 (ET)

12:00:00

Major Averages Broadly Lower as Tech Stocks Decline

News

GPCR FAQ — answered by Alphio AI

Structure Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing oral small molecule treatments for chronic metabolic and cardiopulmonary conditions with significant unmet medical needs. Its programs include Aleniglipron (GSBR-1290), ACCG-2671, GIP and GCG Receptor Oral Small Molecule Obesity Programs, ANPA-0073, and LTSE-2578. Its Aleniglipron is an oral and biased small molecule agonist of GLP-1R, a validated GPCR drug target for obesity. ACCG-2671 is an oral small molecule amylin receptor agonist for obesity. ANPA-0073 is a biased agonist targeting the apelin (APJ) receptor agonist. Its LTSE-2578, an Oral Small Molecule LPA1R Antagonist for IPF. It is developing an antagonist that targets lysophosphatidic acid 1 receptor (LPA1R), a GPCR implicated in responses to tissue injury and pro-fibrotic processes, for the treatment of IPF. It is developing oral incretins for potential combination therapy with GLP-1R or amylin candidates. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

Structure Therapeutics Inc (GPCR) is currently priced at $47.37, which is significantly lower than the analyst price target of $111 from Canaccord. However, the stock has a low RSI of 22.854, indicating it is oversold, but it also has a negative forward P/E ratio of 0, suggesting uncertainty about future earnings. The main risk is the declining net income, with a loss of $106,159,000 reported in Q2 2026, which raises concerns about the company's financial health.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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