Quest Diagnostics Inc (DGX) News & EventsDGXQuest Diagnostics Inc

Quest Diagnostics Haystack MRD Test Shows Excellent Performance in Colorectal Cancer Study

Quest Diagnostics announced that a new study published in The Journal of Molecular Diagnostics showed that Quest's Haystack MRD test is highly accurate at detecting residual and recurrent disease, demonstrating clinical performance in specimens from the landmark DYNAMIC colorectal cancer trial series. The study also validated the test's analytical performance across 23 solid tumor types. Haystack MRD is an ultrasensitive circulating tumor DNA, or ctDNA, liquid biopsy test for identifying residual or recurrent disease in patients with solid tumor cancers. The study evaluated the clinical performance of the commercially available Haystack MRD test by retrospectively testing residual specimens from patients enrolled in the DYNAMIC and DYNAMIC-III trials, which evaluated the use of ctDNA-based MRD results to guide chemotherapy decisions in stage II and III colorectal cancer. In this cohort, Haystack MRD results were highly associated with recurrence, demonstrating 100% sensitivity and 100% specificity at 3-year follow-up and 83.3% sensitivity and 100% specificity at 5-year follow-up. In addition, the study examined a real-world clinical cohort from an Early Experience program in which Haystack MRD detected ctDNA across 27 solid tumor types, including at ultra-low concentrations, with 42% of positive results below 0.5 mean ctDNA molecules/mL.

Dow Falls, Nasdaq Rises as Oil Prices Ease Slightly

The major averages had a mixed day, with the Dow falling, the Nasdaq climbing and the S&P barely budging as oil prices eased fractionally following yesterday's sharp decline. Oil prices pulled back after Iran reportedly offered to reopen the Strait of Hormuz within seven days, while Saudi Arabia is also reportedly planning to resume its East-West pipeline as soon as this week.Get caught up quickly on the top news and calls moving stocks with these five Top Five lists.1. STOCK NEWS:AutoZonereported better-than-expected Q4 EPS, with total company same-store sales rising 1.5%Shares of Quest Diagnosticsand LabCorpwere slipping after CMS announced new preliminary Medicare payment rates for lab servicesBinance is investing $100M in Circle InternetRoyal Caribbeanis near a $6B deal for Sandals Resorts, FT reportsOpenAI has introduced cheaper GPT-6 family models2. WALL STREET CALLS:HSBC downgraded Netflixon viewer share loss to Alphabet'sYouTubeMetLifeupgraded to Overweight at Piper SandlerEricssondowngraded to Underweight at Morgan StanleyNorthcoast upgraded Brinkerto Buy on Chili's growthEldorado Golddouble upgraded to Buy at BofA after Gr eek site visits3. AROUND THE WEB:Nvidia'svaluation at less than 17-times next 12 months earnings is the cheapest level in more than a decade, Bloomberg reportsSoftBankis looking to issue $10B of securities and EUR 1B in debt to fund its OpenAI investment, in what would be one of the biggest junk bond sales yet, Bloomberg reportsGoldman Sachshas emerged as the lead bidder to acquire Palmer Square Capital Management, a credit manager that oversees $37B, Bloomberg saysAlibabais accelerating its vertically integrated AI strategy with the Zhenwu V900, whose larger GPU memory and bandwidth deliver roughly 3x the performance of its predecessor released just four months ago, WSJ reportsKrogerhas removed Red Bull and Boar's Head products at many stores because the company isn't accepting their price hikes, Bloomberg says4. MOVERS:Viking Therapeuticsgained after reporting results from its maintenance study of VK2735Grab Holdingsrose after its CEO bought $29.9M in common stockPelotonwas higher after launching its foldable Peloton Tread Flex and partnering with Miley for its "Let Yourself Run" campaignCharles Schwabfell after Investor's Business Daily reported the company is experiencing AI competition from VanguardCelldexwas lower after announcing results from its Phase 3 EMBARQ-CSU1 and EMBARQ-CSU2 trials5. EARNINGS/GUIDANCE:Thor Industriesreported Q4 results, with CEO Bob Martin noting the quarter was "more challenging" than expectedOn Holdingprovided guidance for Q3 and FY26MillerKnollreported Q1 results, with EPS beating consensusRoundtableannounced its outlook for Q1 and FY27Here Groupreported Q4 results, with EPS and revenue lower year-over-yearINDEXES:The Dow fell 185.14, or 0.36%, to 51,863.69, the Nasdaq gained 122.18, or 0.45%, to 27,244.28, and the S&P 500 declined 0.06, or 0.00%, to 7,764.64.

Dow Falls Nearly 300 Points, Nasdaq Rises Nearly 100 Points

The major averages were mixed near noon, with the Dow falling almost 300 points but the Nasdaq climbing nearly 100 points as oil prices eased fractionally following yesterday's sharp decline. Oil prices were slipping after Iran reportedly offered to reopen the Strait of Hormuz within seven days, while Saudi Arabia is also reportedly planning to resume its East-West pipeline as soon as this week.Get caught up quickly on the top news and calls moving stocks with these five Top Five lists.1. STOCK NEWS:AutoZonereported better-than-expected Q4 EPS, with total company same-store sales rising 1.5%Shares of Quest Diagnosticsand LabCorpwere slipping after CMS announced new preliminary Medicare payment rates for lab servicesBinance is investing $100M in Circle InternetThird-party data suggested strong initial interest in Meta'sMuse, which reached the number one position on the U.S. iOS App Store in the Productivity category shortly after launchPayPalis partnering with Meta on checkouts for purchases using Muse personal agents2. WALL STREET CALLS:HSBC downgraded Netflixon viewer share loss to Alphabet'sYouTubeMetLifeupgraded to Overweight at Piper SandlerEricssondowngraded to Underweight at Morgan StanleyNorthcoast upgraded Brinkerto Buy on Chili's growthEldorado Golddouble upgraded to Buy at BofA after Gr eek site visits3. AROUND THE WEB:SoftBankis looking to issue $10B of securities and EUR 1B in debt to fund its OpenAI investment, in what would be one of the biggest junk bond sales yet, Bloomberg reportsGoldman Sachshas emerged as the lead bidder to acquire Palmer Square Capital Management, a credit manager that oversees $37B, Bloomberg saysAlibabais accelerating its vertically integrated AI strategy with the Zhenwu V900, whose larger GPU memory and bandwidth deliver roughly 3x the performance of its predecessor released just four months ago, WSJ reportsKrogerhas removed Red Bull and Boar's Head products at many stores because the company isn't accepting their price hikes, Bloomberg saysMicrosoftis cutting another 500 jobs, primarily in Xbox, as it continues restructuring and downsizing its gaming business following broader July layoffs, Business Insider reports4. MOVERS:Viking Therapeuticsgains after reporting results from its maintenance study of VK2735Grab Holdingsincreases in New York after its CEO bought $29.9M in common stockPelotonhigher after launching its foldable Peloton Tread Flex and partnering with Miley for its "Let Yourself Run" campaignAbivaxfalls in New York after appointing Rabbat as Chief Medical OfficerCelldexlower after announcing results from its Phase 3 EMBARQ-CSU1 and EMBARQ-CSU2 trials5. EARNINGS/GUIDANCE:Thor Industriesreported Q4 results, with CEO Bob Martin noting the quarter was "more challenging" than expectedOn Holdingprovided guidance for Q3 and FY26MillerKnollreported Q1 results, with EPS beating consensusRoundtableannounced its outlook for Q1 and FY27Here Groupreported Q4 results, with EPS and revenue lower year-over-yearINDEXES:Near midday, the Dow was down 281.06, or 0.54%, to 51,767.77, the Nasdaq was up 78.77, or 0.29%, to 27,200.86, and the S&P 500 was down 3.94, or 0.05%, to 7,760.76.