CytomX Therapeutics Inc

CytomX Therapeutics Inc (CTMX) Stock Analysis

$2.280

-0.123 (-5.39%)At close

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High
2.450
Open
2.400
VWAP
2.33
Volume
3.18M
Mkt Cap
98.18M
Low
2.260
Amount
7.41M
EV/EBITDA, TTM
-1.21

CytomX Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company. The Company is focused on developing conditionally activated, masked biologics designed to be localized to the tumor microenvironment. The Company is developing a pipeline of localized biologics, through its PROBODY therapeutic platform. Its pipeline comprises therapeutic candidates across multiple treatment modalities, including ADCs, T-cell engagers, and immune modulators such as cytokines. Its clinical-stage pipeline includes CX-2051, CX-904 and CX-801. CX-2051 is a masked, conditionally activated ADC directed toward EpCAM, armed with a topoisomerase-1 inhibitor payload. CX-904 is a masked, conditionally activated T-cell-engaging bispecific antibody targeting the EGFR on tumor cells and the CD3 receptor on T cells. CX-801 is a masked interferon alpha-2b PROBODY cytokine with broad potential applicability in traditionally immuno-oncology-sensitive as well as insensitive (cold) tumors.

cytomx.com

AI analysis of CytomX Therapeutics Inc (CTMX)

Sell

CytomX Therapeutics Inc is not a good buy right now. The current price is $2.28, which is significantly below the average analyst price target of $11 to $14, indicating potential upside. However, the stock has seen a staggering 46.35% year-to-date decline and a 92.4% year-over-year revenue drop to $1.42 million, which raises serious concerns about its financial health. The RSI is at 33.876, indicating oversold conditions, but the overall negative sentiment from recent earnings misses and cash reserve declines suggests caution. The main risk is the company's substantial revenue decline and ongoing losses, as evidenced by a net income of -$20.67 million in Q2 2026, which could further impact investor confidence and stock performance.

Analyst Ratings (7)

+294.74% upside
Buy
6 Buy
1 Hold
0 Sell
Current: 2.28
Low
6.00
Average
9.00
High
10.00

JPMorgan

2026-08-13

Price Target

$11

Overweight

Guggenheim

2026-08-10

Price Target

$14

Buy

Wolfe Research

2026-05-19

Price Target

$6

Outperform

H.C. Wainwright

2026-05-11

Price Target

$11

Buy

Piper Sandler

2026-03-23

Price Target

$12

Overweight

Valuation Metrics

The current forward P/E ratio for CytomX Therapeutics Inc (CTMX) is 14.20, compared to its 5-year average forward P/E of 15.74.

Forward P/E

Fair
5Y Average P/E
15.74
Current P/E
14.20
Overvalued
85.98
Undervalued
-54.50

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-13.19
Current EV/EBITDA
-1.21
Overvalued
41.21
Undervalued
-67.60

Forward P/S

Fair
5Y Average P/S
8.43
Current P/S
20.72
Overvalued
21.71
Undervalued
-4.85

Alphio AI Price Scenarios for CTMX

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%CTMX

$4.13

Scenario price

B

Base

Base · 50%CTMX

$3.13

Scenario price

B

Bear

Bear · 25%CTMX

$2.59

Scenario price

Whales holding CTMX

A

ADAR1 Capital Management, LLC

+ HoldingCTMX

-16.51%

3M Return

P

Perceptive Advisors LLC

+ HoldingCTMX

-17.84%

3M Return

V

VR Management, LLC

+ HoldingCTMX

-31.99%

3M Return

Events Timeline

2026-08-27 (ET)

08:30:00

CytomX Therapeutics' Varseta-M Receives FDA Fast Track Designation

2026-08-06 (ET)

18:00:00

CytomX Reports Q2 Revenue of $1.42M, Below Consensus

2026-08-03 (ET)

08:30:00

CytomX Therapeutics Appoints Alejandra Carvajal as Chief Legal Officer

2026-06-03 (ET)

08:10:00

CytomX Expands Collaboration Agreement with Regeneron

2026-05-07 (ET)

18:20:00

CytomX Reports Q1 Revenue of $10.26M

News

CTMX FAQ — answered by Alphio AI

CytomX Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company. The Company is focused on developing conditionally activated, masked biologics designed to be localized to the tumor microenvironment. The Company is developing a pipeline of localized biologics, through its PROBODY therapeutic platform. Its pipeline comprises therapeutic candidates across multiple treatment modalities, including ADCs, T-cell engagers, and immune modulators such as cytokines. Its clinical-stage pipeline includes CX-2051, CX-904 and CX-801. CX-2051 is a masked, conditionally activated ADC directed toward EpCAM, armed with a topoisomerase-1 inhibitor payload. CX-904 is a masked, conditionally activated T-cell-engaging bispecific antibody targeting the EGFR on tumor cells and the CD3 receptor on T cells. CX-801 is a masked interferon alpha-2b PROBODY cytokine with broad potential applicability in traditionally immuno-oncology-sensitive as well as insensitive (cold) tumors. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

CytomX Therapeutics Inc is not a good buy right now. The current price is $2.28, which is significantly below the average analyst price target of $11 to $14, indicating potential upside. However, the stock has seen a staggering 46.35% year-to-date decline and a 92.4% year-over-year revenue drop to $1.42 million, which raises serious concerns about its financial health. The RSI is at 33.876, indicating oversold conditions, but the overall negative sentiment from recent earnings misses and cash reserve declines suggests caution. The main risk is the company's substantial revenue decline and ongoing losses, as evidenced by a net income of -$20.67 million in Q2 2026, which could further impact investor confidence and stock performance.

7 analysts cover CTMX: 6 rate it Buy, 1 Hold and 0 Sell. The average price target is 9.00.

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This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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