CytomX Therapeutics Inc

CytomX Therapeutics Inc (CTMX) Stock Analysis

$3.210

-0.197 (-6.14%)At close

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High
3.420
Open
3.400
VWAP
3.28
Vol
2.17M
Mkt Cap
98.18M
Low
3.210
Amount
7.13M
EV/EBITDA, TTM
-1.73

CytomX Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company. The Company is focused on developing conditionally activated, masked biologics designed to be localized to the tumor microenvironment. The Company is developing a pipeline of localized biologics, through its PROBODY therapeutic platform. Its pipeline comprises therapeutic candidates across multiple treatment modalities, including ADCs, T-cell engagers, and immune modulators such as cytokines. Its clinical-stage pipeline includes CX-2051, CX-904 and CX-801. CX-2051 is a masked, conditionally activated ADC directed toward EpCAM, armed with a topoisomerase-1 inhibitor payload. CX-904 is a masked, conditionally activated T-cell-engaging bispecific antibody targeting the EGFR on tumor cells and the CD3 receptor on T cells. CX-801 is a masked interferon alpha-2b PROBODY cytokine with broad potential applicability in traditionally immuno-oncology-sensitive as well as insensitive (cold) tumors.

cytomx.com

AI analysis of CytomX Therapeutics Inc (CTMX)

hold

CytomX Therapeutics Inc is currently trading at $3.21, with a significant recent decline in revenue of 92.4% year-over-year reported in Q2. Despite receiving FDA Fast Track Designation for its lead candidate Varseta-M, the company faces challenges with profitability and cash reserves, which decreased from $346.7M to $330.3M. The RSI is at 37.147, indicating potential oversold conditions, but the overall financial health remains concerning. Therefore, while there are potential catalysts, the risks outweigh the current buying opportunity, suggesting a hold position.

Analyst Ratings (7)

+180.37% upside
Buy
6 Buy
1 Hold
0 Sell
Current: 3.21
Low
6.00
Average
9.00
High
10.00

JPMorgan

2026-08-13

Price Target

$11

Overweight

Guggenheim

2026-08-10

Price Target

$14

Buy

Wolfe Research

2026-05-19

Price Target

$6

Outperform

H.C. Wainwright

2026-05-11

Price Target

$11

Buy

Piper Sandler

2026-03-23

Price Target

$12

Overweight

Valuation Metrics

The current forward P/E ratio for CytomX Therapeutics Inc (CTMX) is 14.20, compared to its 5-year average forward P/E of 15.26.

Forward P/E

Fair
5Y Average P/E
15.26
Current P/E
14.20
Overvalued
85.63
Undervalued
-55.10

Forward EV/EBITDA

Fair
5Y Average EV/EBITDA
-13.20
Current EV/EBITDA
-1.73
Overvalued
41.25
Undervalued
-67.64

Forward P/S

Overvalued
5Y Average P/S
7.85
Current P/S
29.41
Overvalued
20.83
Undervalued
-5.13

Alphio AI Price Scenarios for CTMX

Scenario prices are the last monthly forecast band of the current year. Probabilities are fixed model weights (25 / 50 / 25), not guarantees.

B

Bull

Bull · 25%CTMX

$4.13

Scenario price

B

Base

Base · 50%CTMX

$3.13

Scenario price

B

Bear

Bear · 25%CTMX

$2.59

Scenario price

Whales holding CTMX

V

VR Management, LLC

+ HoldingCTMX

+4.71%

3M Return

P

Perceptive Advisors LLC

+ HoldingCTMX

+4.39%

3M Return

A

ADAR1 Capital Management, LLC

+ HoldingCTMX

+2.25%

3M Return

Events Timeline

2026-08-27 (ET)

08:30:00

CytomX Therapeutics' Varseta-M Receives FDA Fast Track Designation

2026-08-06 (ET)

18:00:00

CytomX Reports Q2 Revenue of $1.42M, Below Consensus

2026-08-03 (ET)

08:30:00

CytomX Therapeutics Appoints Alejandra Carvajal as Chief Legal Officer

2026-06-03 (ET)

08:10:00

CytomX Expands Collaboration Agreement with Regeneron

2026-05-07 (ET)

18:20:00

CytomX Reports Q1 Revenue of $10.26M

News

CTMX FAQ — answered by Alphio AI

CytomX Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company. The Company is focused on developing conditionally activated, masked biologics designed to be localized to the tumor microenvironment. The Company is developing a pipeline of localized biologics, through its PROBODY therapeutic platform. Its pipeline comprises therapeutic candidates across multiple treatment modalities, including ADCs, T-cell engagers, and immune modulators such as cytokines. Its clinical-stage pipeline includes CX-2051, CX-904 and CX-801. CX-2051 is a masked, conditionally activated ADC directed toward EpCAM, armed with a topoisomerase-1 inhibitor payload. CX-904 is a masked, conditionally activated T-cell-engaging bispecific antibody targeting the EGFR on tumor cells and the CD3 receptor on T cells. CX-801 is a masked interferon alpha-2b PROBODY cytokine with broad potential applicability in traditionally immuno-oncology-sensitive as well as insensitive (cold) tumors. It operates in the Healthcare sector (PHARMACEUTICAL PREPARATIONS industry).

CytomX Therapeutics Inc is currently trading at $3.21, with a significant recent decline in revenue of 92.4% year-over-year reported in Q2. Despite receiving FDA Fast Track Designation for its lead candidate Varseta-M, the company faces challenges with profitability and cash reserves, which decreased from $346.7M to $330.3M. The RSI is at 37.147, indicating potential oversold conditions, but the overall financial health remains concerning. Therefore, while there are potential catalysts, the risks outweigh the current buying opportunity, suggesting a hold position.

7 analysts cover CTMX: 6 rate it Buy, 1 Hold and 0 Sell. The average price target is 9.00.

This page is for research only and is not investment advice. Models can be wrong. Past performance does not guarantee future results.

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